Listar por autor 

Listar por autor "Prados Carvajal, Rosario"              

Mostrando ítems 1-8 de 8

    • Artículo
      Icon

      ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair 

      Jimeno González, Sonia; Prados Carvajal, Rosario; Fernández Ávila, María Jesús; Pinela Da Silva, Sonia Cristina; Silvestris, Domenico Alessandro; Endara Coll, Martin; Rodríguez Real, Guillermo; Domingo Prim, Judit; Mejías Navarro, Fernando; Romero Franco, Amador; Jimeno González, Silvia; Barroso, Sonia; Cesarini, Valeriana; Aguilera López, Andrés; Gallo, Angela; Visa, Neus; Huertas Sánchez, Pablo (Nature Publishing Group, 2021)
      The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA ...
    • Artículo
      Icon

      Centriolar Subdistal Appendages Promote Double-strand Break Repair Through Homologous Recombination 

      Rodriguez Real, Guillermo; Domínguez Calvo, Andrés; Prados Carvajal, Rosario; Bayona Feliu, Aleix; Gomes Pereira, Sonia; Romero Balestra, Fernando; Huertas Sánchez, Pablo (1469-3178, 2023)
      The centrosome is a cytoplasmic organelle with roles in microtu-bule organization that has also been proposed to act as a ...
    • Tesis Doctoral
      IconIcon

      Crosstalk between DNA end resection and RNA metabolism 

      Prados Carvajal, Rosario (2020-01-23)
      DNA suffers thousands of lesions from exogenous and endogenous sources. Nevertheless, double-strand breaks (DSBs) are the ...
    • Artículo
      Icon

      CtIP-mediated Alternative mRNA Splicing Fine-tunes the DNA Damage Response 

      Prados Carvajal, Rosario; Rodríguez Real, Guillermo; Gutiérrez Pozo, Gabriel; Huertas Sánchez, Pablo (Cold Spring Harbor Laboratory Press, 2021)
      In order to survive to the exposure of DNA damaging agents, cells activate a complex response that coordinates the cellular ...
    • Artículo
      Icon

      Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1 

      Hernández, Gonzalo; Ramirez, María José; Minguillón, Jordi; Quiles, Paco; Huertas Sánchez, Pablo; Prados Carvajal, Rosario (Nature Publishing Group, 2018)
      BRCA1 is a tumor suppressor that regulates DNA repair by homologous recombination. Germline mutations in BRCA1 are associated ...
    • Artículo
      Icon

      EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks 

      Domingo Prim, Judit; Endara Coll, Martin; Bonath, Franziska; Prados Carvajal, Rosario; Friedländer, Marc R.; Visa, Neus; Huertas Sánchez, Pablo; Jimeno González, Sonia (Nature Research, 2019)
      The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is ...
    • Artículo
      Icon

      Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair 

      Prados Carvajal, Rosario; Huertas Sánchez, Pablo; Gavish Izakson, Michal; Bhavana Velpula, Bhagya; Elkon, Ran (Oxford University Press, 2018)
      The DNA damage response (DDR) is an extensive signaling network that is robustly mobilized by DNA double-strand breaks ...
    • Artículo
      Icon

      The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures 

      Jimeno González, Sonia; Camarillo Daza, María Rosa; Mejías Navarro, Fernando; Fernández Ávila, Mª Jesús; Soria Bretones, Isabel; Prados Carvajal, Rosario; Huertas Sánchez, Pablo (Elsevier, 2018)
      DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination ...