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Listar por autor "Pascual, Alberto"
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Artículo
Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo
Serrano Pozo, Alberto; Sánchez García, Manuel A.; Heras Garvín, Antonio; March Díaz, Rosana Rocío; Navarro Garrido, Victoria; Vizuete Chacón, María Luisa; López Barneo, José; Vitorica Ferrández, Francisco Javier; Pascual, Alberto (Public Library of Science, 2017)Background Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number ...
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Cloning and expression of the algL gene, encoding the Azotobacter chroococcum alginate lyase: Purification and characterization of the enzyme
Peciña, Ana; Pascual, Alberto; Paneque Guerrero, Antonio (American Society for Microbiology, 1999)The alginate lyase-encoding gene (algL) of Azotobacter chroococcum was localized to a 3.1-kb EcoRI DNA fragment that ...
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Fundamental physical cellular constraints drive self-organization of tissues
Sánchez Gutiérrez, Daniel; Tozluoglu, Melda; Barry, Joseph D.; Pascual, Alberto; Mao, Yanlan; Escudero Cuadrado, Luis María (Wiley-Blackwell, 2016)Morphogenesis is driven by small cell shape changes that modulate tissue organization. Apical surfaces of proliferating ...
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Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1
March Diaz, Rosana; Lara Ureña, Nieves; Romero Molina, Carmen; Heras Garvin, Antonio; Ortega de San Luis, Clara; Alvarez Vergara, Maria I.; Navarro Garrido, Victoria; Sánchez Mico, María Victoria; Vizuete Chacón, María Luisa; López Barneo, José; Vitorica Ferrández, Francisco Javier; Pascual, Alberto (Springer, 2021)Genetic Alzheimer’s disease (AD) risk factors associate with reduced defensive amyloid β plaque-associated microglia (AβAM), ...
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Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia
Romero-Ruiz, Antonio; Bautista, Lucía; Navarro, Virginia; Heras Garvín, Antonio; Castellano Orozco, Antonio Gonzalo; López Barneo, José; Pascual, Alberto (American Society for Biochemistry and Molecular Biology, 2012-02-03)Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ...
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Substantia nigra dopaminergic neurons and striatalinterneurons are engaged in three parallel but interdependentpostnatal neurotrophic circuits
Ortega de San Luís, Clara; Sánchez García, Manuel A.; Nieto González, José Luis; García-Junco Clemente, Pablo; Montero Sánchez, Adoración; Fernández-Chacón, Rafael; Pascual, Alberto (Anatomical Society of Great Britain and Ireland, 2018-06-11)The striatum integrates motor behavior using a well‐defined microcircuit whose individual components are independently ...
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Substrate binding and catalysis by ribonuclease P from cyanobacteria and Escherichia coli are affected differently by the 3′ terminal CCA in tRNA precursors
Pascual, Alberto; Vioque Peña, Agustín (The National Academy of Sciences, 1999)We have studied the effect of the 3′ terminal CCA sequence in precursors of tRNAs on catalysis by the RNase P RNA or the ...