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Artículo
An evolutionary analysis of the reaction mechanisms of photosystem I reduction by cytochrome c6 and plastocyanin
Rosa Acosta, Miguel Ángel de la; Navarro Carruesco, José Antonio; Díaz Quintana, Antonio Jesús; Cerda Haynes, Berta de la; Molina Heredia, Fernando Publio; Balme, Alexis; Murdoch, Piedad del Socorro; Díaz Moreno, Irene; Durán Díaz, Raúl V.; Hervás Morón, Manuel (Elsevier, 2002)Photosystem I reduction by the soluble metalloproteins cytochrome c6 and plastocyanin, which are alternatively synthesized ...
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Downregulation of Glutamine Synthetase, notglutaminolysis, is responsible for glutamine addiction inNotch1-driven acute lymphoblastic leukemia
Nguyen, Tra Ly; Nokin, Marie Julie; Terés, Silvia; Tomé, Mercedes; Bodineau, Clément; Galmar, Oriane; Murdoch, Piedad del Socorro; Durán Díaz, Raúl V. (Wiley, 2021)The cellular receptor Notch1 is a central regulator of T-cell development, and as a consequence, Notch1 pathway appears ...
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Exopolysaccharide Production by Sinorhizobium fredii HH103 Is Repressed by Genistein in a NodD1-Dependent Manner
Acosta Jurado, Sebastián; Navarro Gómez, Pilar; Murdoch, Piedad del Socorro; Crespo Rivas, Juan Carlos; Shi Jie; Cuesta Berrio, Lidia; Ruiz Sainz, José Enrique; Rodríguez Carvajal, Miguel Ángel; Vinardell González, José María (Public Library of Science, 2016)In the rhizobia-legume symbiotic interaction, bacterial surface polysaccharides, such as exopolysaccharide (EPS), ...
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Glutamine, MTOR and autophagy: a multiconnection relationship
Bodineau, Clément; Tomé, Mercedes; Murdoch, Piedad del Socorro; Durán, Raúl V. (Taylor & Francis, 2022)Cancer cells metabolize glutamine mostly through glutaminolysis, a metabolic pathway that activates MTORC1. The AMPK-MTORC1 ...
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Intermolecular displacement of S-bound L-methionine on platinum(II) by guanosine 5′-monophosphate: Implications for the mechanism of action of anticancer drugs
Barnham, Kevin J.; Djuran, Milos I.; Murdoch, Piedad del Socorro; Sadler, Peter J. (Chemical Society, 1994)NMR investigations of the kinetics and thermodynamics of the competitive binding of L-methionine (Met), L-histidine (His), ...
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The rkpU gene of Sinorhizobium fredii HH103 is required for bacterial K-antigen polysaccharide production and for efficient nodulation with soybean but not with cowpea
Hidalgo Perea, Ángeles; Margaret Oliver, Isabel María; Crespo Rivas, Juan Carlos; Parada Ibáñez, Maribel Eugenia; Murdoch, Piedad del Socorro; López, Abigail; Buendía Clavería, Ana María; Moreno Onorato, Francisco Javier; Gil Serrano, Antonio Miguel; Rodríguez Carvajal, Miguel Ángel; Ruiz Sainz, José Enrique; Vinardell González, José María (Society for General Microbiology, 2010)In this work, the role of the rkpU and rkpJ genes in the production of the K-antigen polysaccharides (KPS) and in the ...
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Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis
Bodineau, Clément; Tomé, Mercedes; Murdoch, Piedad del Socorro; Courtois, Sarah; Durán Díaz, Raúl V.; Sciacovelli, Marco (Nature Research, 2021)Glutamoptosis is the induction of apoptotic cell death as a consequence of the aberrant activation of glutaminolysis and ...