- idUS
- Listar por autor
Listar por autor "González Prieto, Román"
Mostrando ítems 1-12 de 12
-
Artículo
A disease-associated XPA Allele Interferes with TFIIH Binding and Primarily Affects Transcription-coupled Nucleotide Excision Repair
van den Heuvel, Diana; Kim, Mihyun; Wondergem, Annelotte P.; van der Meer, Paula J.; Witkamp, Myrèse; Lambregtse, Ferdy; Kim, Hyun Suk; Kan, Folkert; Apelt, Katja; Kragten, Angela; González Prieto, Román; Luijsterburg, Martijn S. (National Academy of Sciences, 2023)XPA is a central scaffold protein that coordinates the assembly of repair complexes in the global genome (GG-NER) and ...
-
Artículo
Application of flow focusing to the break-up of a magnetite suspension jet for the production of paramagnetic microparticles
Martín Banderas, Lucía; González Prieto, Román; Rodríguez Gil, Alfonso; Fernández Arévalo, María Mercedes; Flores Mosquera, María; Chávez de Diego, Sebastián; Gañán-Calvo, Alfonso M. (2011)Paramagnetic particles offer an extensive improvement in the magnetic separation or purification of a wide variety of ...
-
Artículo
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote continuous DNA synthesis
Salas Lloret, Daniel; García Rodríguez, Néstor; Soto Hidalgo, Emily; González Vinceiro, Lourdes; Espejo Serrano, Carmen; Giebel, Lisanne; Huertas Sánchez, Pablo; González Prieto, Román (Nature Research, 2024-05-20)Deficiencies in the BRCA1 tumor suppressor gene are the main cause of hereditary breast and ovarian cancer. BRCA1 is ...
-
Artículo
CD44 Acts as a Coreceptor for Cell-specific Enhancement of Signaling and Regulatory T Cell Induction by TGM1, a Parasite TGF-β Mimic
van Dinther, Maarten; Cunningham, Kyle T.; Singh, Shashi Prakash; White, Madeleine P.J.; Campion, Tiffany; Ciancia, Claire; van Veelen, Peter A.; de Ru, Arnoud H.; González Prieto, Román; Mukundan, Ananya; Maizels, Rick M. (National Academy of Sciences, 2023)Long-lived parasites evade host immunity through highly evolved molecular strategies. The murine intestinal helminth, ...
-
Artículo
dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe
Rodrigues, Joana S.; Chenlo, Miguel; Bravo, Susana B.; Pérez Romero, Sihara; Suárez Fariña, María; Sobrino, Tomás; Sanz Pamplona, Rebeca; González Prieto, Román; Álvarez, Clara V. (Springer Nature, 2024-05-14)The E3 SUMO ligase PIAS2 is expressed at high levels in differentiated papillary thyroid carcinomas but at low levels in ...
-
Artículo
Exploration of nuclear body-enhanced sumoylation reveals that PML represses 2-cell features of embryonic stem cells
Tessier, Sarah; Ferhi, Omar; Geoffroy, Marie-Claude; González Prieto, Román; Canat, Antoine; Quentin, Samuel; Pla, Marika; Niwa-Kawakita, Michiko; Bercier, Pierre; Rerolle, Domitille; Therizols, Pierre; Fabre, Emmanuelle; Vertegaal, Alfred C. O.; de Thé, Hugues; Lallemand-Breitenbach, Valerie (Springer Nature, 2022)Membrane-less organelles are condensates formed by phase separation whose functions often remain enigmatic. Upon oxidative ...
-
Artículo
Non-recombinogenic roles for Rad52 in translesion synthesis during DNA damage tolerance
Cano Linares, María Isabel; Yáñez Vilches, Aurora; García Rodríguez, Néstor; Barrientos Moreno, Marta; González Prieto, Román; San Segundo, Pedro; Ulrich, Helle D.; Prado, Félix (Wiley-Blackwell, 2021)DNA damage tolerance relies on homologous recombination (HR) and translesion synthesis (TLS) mechanisms to fill in the ...
-
Artículo
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
Yáñez Vilches, Aurora; Romero, Antonia M.; Barrientos Moreno, Marta; Cruz, Esther; González Prieto, Román; Sharma, Sushma; Vertegaal, Alfred C.O.; Prado, Félix (Public Library of Science, 2024-05-22)The helicase MCM and the ribonucleotide reductase RNR are the complexes that provide the substrates (ssDNA templates and ...
-
Artículo
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
Nguyen, Binh An; Singh, Virender; Afrin, Shumaila; Yakubovska, Anna; Wang, Lanie; Ahmed, Yasmin; González Prieto, Román; Saelices, Lorena (Nature Research, 2024-01-17)ATTR amyloidosis is caused by the deposition of transthyretin in the form of amyloid fibrils in virtually every organ of ...
-
Artículo
SUMO-activated Target Traps (SATTs) Enable the Identification of a Comprehensive E3-specific SUMO Proteome
Salas Lloret, Daniel; Jansen, Nicolette S.; Nagamalleswari, Easa; van der Meulen, Coen; Gracheva, Ekaterina; de Ru, Arnoud H.; Otte, H. Anne Marie; van Veelen, Peter A.; Pichler, Andrea; Goedhart, Joachim; Vertegaal, Alfred C.O.; González Prieto, Román (American Association for the Advancement of Science, 2023)Ubiquitin and ubiquitin-like conjugation cascades consist of dedicated E1, E2, and E3 enzymes with E3s providing substrate ...
-
Artículo
Ubiquitinome Profiling Reveals in Vivo UBE2D3 Targets and Implicates UBE2D3 in Protein Quality Control
Yalçin, Zeliha; Koot, Daniëlle; Bezstarosti, Karel; Salas Lloret, Daniel; Bleijerveld, Onno B.; Boersma, Vera; Falcone, Mattia; González Prieto, Román; Altelaar, Maarten; Demmers, Jeroen A.A.; Jacobs, Jacqueline J.L. (Elsevier, 2023)Ubiquitination has crucial roles in many cellular processes, and dysregulation of ubiquitin machinery enzymes can result ...
-
Artículo
XPC–PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair
Blessing, Charlotte; Apelt, Katja; Van Den Heuvel, Diana; González Leal, Claudia; Rother, Magdalena B; Van Der Woude, Melanie; González Prieto, Román; Luijsterburg, Martijn S. (Springer Nature, 2022)Cells employ global genome nucleotide excision repair (GGR) to eliminate a broad spectrum of DNA lesions, including those ...