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Listar por autor "Gómez Cabello, Daniel"
Mostrando ítems 1-8 de 8
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Artículo
A genome-wide screening uncovers the role of CCAR2 as an antagonist of DNA end resection
López Saavedra, Ana; Gómez Cabello, Daniel; Domínguez Sánchez, María Salud; Mejías Navarro, Fernando; Fernández Ávila, María Jesús; Martínez Macías, María Isabel; Huertas Sánchez, Pablo (Nature Publishing Group, 2016)There are two major and alternative pathways to repair DNA double-strand breaks: non-homologous end-joining and homologous ...
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Artículo
CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway
Gómez Cabello, Daniel; Pappas, George; Aguilar Morante, Diana; Dinant, Christoffel; Bartek, Jiri (Springer Nature, 2022)The RNA world is changing our views about sensing and resolution of DNA damage. Here, we develop single-molecule DNA/RNA ...
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Artículo
CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells
Gómez Cabello, Daniel; Checa Rodríguez, Cintia; Abad, María; Serrano, Manuel; Huertas Sánchez, Pablo (Elsevier, 2017)Acquired genomic instability is one of the major concerns for the clinical use of induced pluripotent stem cells (iPSCs). ...
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Artículo
MDC1 maintains active elongation complexes of RNA polymerase II
Pappas, George; Munk, Sebastian Howen Nesgaard; Watanabe, Kenji; Thomas, Quentin; Gal, Zita; Gram, Helena Hagner; Lee, MyungHee; Gómez Cabello, Daniel; Bartek, Jiri (Elsevier, 2023)The role of MDC1 in the DNA damage response has been extensively studied; however, its impact on other cellular processes ...
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Artículo
Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
Jimeno González, Sonia; Fernández Ávila, María Jesús; Cruz García, Andrés; Cepeda García, Cristina; Gómez Cabello, Daniel; Huertas Sánchez, Pablo (Oxford University Press, 2015)DNA double strand breaks are the most cytotoxic lesions that can occur on the DNA. They can be repaired by different ...
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Artículo
New tools to study DNA double-strand break repair pathway choice
Gómez Cabello, Daniel; Jimeno González, Sonia; Fernández Ávila, María Jesús; Huertas Sánchez, Pablo (2013) -
Artículo
Therapeutic Opportunities of Disrupting Genome Integrity inAdult Diffuse Glioma
Aguilar Morante, Diana; Gómez Cabello, Daniel; Quek, Hazel; Liu, Tianqing; Hamerlik, Petra; Lim, Yi Chieh (MDPI, 2022)Adult diffuse glioma, particularly glioblastoma (GBM), is a devastating tumor of the central nervous system. The existential ...
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Trabajo Fin de Grado
Triple terapia en cáncer: inhibidores de reparación de ADN, radioterapia e inmunoterapia
Gómez Estévez, Paula (2023-06-02)El presente trabajo fin de grado se centra en el estudio de la triple terapia en el cáncer: inhibidores de reparación de ...