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    • Article
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      Ginsenosides act as positive modulators of P2X4 receptors 

      Dhuna, K.; Felgate, M.; Bidula, S.M.; Walpole, Samuel; Bibic, L.; Cromer, B.A.; Angulo Álvarez, Jesús; Sanderson, J.; Stebbing, M.J.; Stokes, L. (American Society for Pharmacology and Experimental Therapeutics (ASPET), 2019)
      We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators ...
    • Article
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      Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 

      Bidula, S.M.; Cromer, B.A.; Walpole, Samuel; Angulo Álvarez, Jesús; Stokes, Leanne (Nature Research (part of Springer Nature): Fully open access journals, 2019)
      P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens ...