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Browsing by Author "Benito, Juan Manuel"
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Article
Cyclodextrin-mediated Crystallization of Acid β-glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues
Brumshtein, Boris; Aguilar Moncayo, Matilde; Benito, Juan Manuel; García Fernández, José Manuel; Silman, Israel; Shaaltiel, Yoseph; Aviezer, David; Sussman, Joel L.; Futerman, Anthony H.; Ortiz Mellet, Carmen (Royal Society of Chemistry, 2011)Cyclodextrin-based host-guest chemistry has been exploited to facilitate co-crystallization of recombinant human acid ...
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Article
Enhanced Gene Delivery Triggered by Dual pH/Redox Responsive Host-Guest Dimerization of Cyclooligosaccharide Star Polycations
Carbajo Gordillo, Ana Isabel; López Fernández, José; Benito, Juan Manuel; Jiménez Blanco, José Luis; Santana Armas, María Luisa; Marcelo, Gema; Ortiz Mellet, Carmen; García Fernández, José Manuel (Wiley, 2022)A robust strategy is reported to build perfectly monodisperse star polycationscombining a trehalose-based cyclooligosaccharide ...
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Article
Pharmacological chaperone therapy for Gaucher disease: A patent review
Benito, Juan Manuel; García Fernández, José Manuel; Ortiz Mellet, Carmen (Taylor & Francis, 2011)Introduction: Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher ...
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Article
Toward a Suitable Structural Analysis of Gene Delivery Carrier Based on Polycationic Carbohydrates by Electron Transfer Dissociation Tandem Mass Spectrometry
Przybylski, Cédric; Benito, Juan Manuel; Bonnet, Véronique; Ortiz Mellet, Carmen; García Fernández, José Manuel (Elsevier, 2016)Polycationic carbohydrates represent an attractive class of biomolecules for several applications and particularly as non ...