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      CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway 

      Gómez Cabello, Daniel; Pappas, George; Aguilar Morante, Diana; Dinant, Christoffel; Bartek, Jiri (Springer Nature, 2022)
      The RNA world is changing our views about sensing and resolution of DNA damage. Here, we develop single-molecule DNA/RNA ...
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      MDC1 maintains active elongation complexes of RNA polymerase II 

      Pappas, George; Munk, Sebastian Howen Nesgaard; Watanabe, Kenji; Thomas, Quentin; Gal, Zita; Gram, Helena Hagner; Lee, MyungHee; Gómez Cabello, Daniel; Bartek, Jiri (Elsevier, 2023)
      The role of MDC1 in the DNA damage response has been extensively studied; however, its impact on other cellular processes ...
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      MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells 

      Sakellariou, Despoina; Bak, Sara Thornby; Isik, Esin; Barroso Ceballos, Sonia Inés; Porro, Antonio; Aguilera López, Andrés; Bartek, Jiri; Janscak, Pavel; Peña Díaz, Javier (Elsevier, 2022)
      Up to 15% of human cancers maintain their telomeres through a telomerase-independent mechanism, termed “alternative ...
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      The human nucleoporin Tpr protects cells from RNA-mediated replication stress 

      Kosar, Martin; Giannattasio, Michele; Piccini, Daniele; Maya Mendoza, Apolinar; García Benítez, Francisco; Bartkova, Jirina; Barroso Ceballos, Sonia Inés; Gaillard, Hélène; Martini, Emanuele; Restuccia, Umberto; Ramírez Otero, Miguel Ángel; Garre, Massimiliano; Verga, Eleonora; Andújar Sánchez, Miguel; Maynard, Scott; Hodny, Zdenek; Costanzo, Vincenzo; Kumar, Amit; Bachi, Angela; Aguilera López, Andrés; Bartek, Jiri; Foiani, Marco (Springer Nature, 2021)
      Although human nucleoporin Tpr is frequently deregulated in cancer, its roles are poorly understood. Here we show that Tpr ...