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Listar por autor "Venero Recio, José Luis"
Mostrando ítems 21-40 de 69
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Artículo
Gal3 Plays a Deleterious Role in a Mouse Model of Endotoxemia
Fernández Martín, Juan Carlos; Espinosa Oliva, Ana María; García Domínguez, Irene; Rosado Sánchez, Isaac; Pacheco, Yolanda María; Moyano, Rosario; Monterde, José G.; Venero Recio, José Luis; Martínez de Pablos, Rocío (Multidisciplinary Digital Publishing Institute (MDPI), 2022)Lipopolysaccharide (LPS)-induced endotoxemia induces an acute systemic inflammatory response that mimics some important ...
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Artículo
Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon
Espinosa Oliva, Ana María; García Miranda, Pablo; Alonso Bellido, Isabel María; Carvajal Vázquez, Ana Eloisa; González Rodríguez, Melania; Carrillo Jiménez, Alejandro; García Domínguez, Irene; Vázquez Carretero, María Dolores; García Revilla, Juan; Santiago Pavón, Martiniano; Peral Rubio, María José; Venero Recio, José Luis; Martínez de Pablos, Rocío (Frontiers Media, 2021)Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the ...
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Artículo
Galectin-3 depletion tames pro-tumoural microglia and restrains cancer cells growth
Rivera Ramos, Alberto; Cruz Hernández, Luis; Talaverón Aguilocho, Rocío; Sánchez Montero, María Teresa; García Revilla, Juan; Mulero Acevedo, Marta; Deierborg, Tomas; Venero Recio, José Luis; Sarmiento Soto, Manuel (Elsevier, 2024-04-16)Galectin-3 (Gal-3) is a multifunctional protein that plays a pivotal role in the initiation and progression of various ...
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Artículo
Galectin-3 is elevated in CSF and is associated with A beta deposits and tau aggregates in brain tissue in Alzheimer's disease
Boza Serrano, Antonio; Vrillon, Agathe; Minta, Karolina; Paulus, Agnes; Camprubí Ferrer, Lluís; García, Megg; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2022)Galectin-3 (Gal-3) is a beta-galactosidase binding protein involved in microglial activation in the central nervous ...
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Artículo
Galectin-3 is upregulated in frontotemporal dementia patients with subtype specificity
Borrego Écija, Sergi; Pérez Millan, Agnès; Antonell, Anna; Fort Aznar, Laura; Kaya Tilki, Elif; León Halcón, Alberto; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Boza Serrano, Antonio (Wiley, 2023-11)INTRODUCTION Neuroinflammation is a major contributor to the progression of frontotemporal dementia (FTD). Galectin-3 ...
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Artículo
Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
Kei Yip, Ping; Carrillo Jiménez, Alejandro; King, Paul; Vilalta, Anna; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Nature, 2017)Traumatic brain injury (TBI) is currently a major cause of morbidity and poor quality of life in Western society, with an ...
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Artículo
Galectin-3 shapes toxic alpha-synuclein strains in Parkinson's disease.
García Revilla, Juan; Boza Serrano, Antonio; Jin, Yiyun; Vadukul, Devkee M.; Soldán Hidalgo, Jesús; Camprubí Ferrer, Lluís; Ruiz Laza, Rocío; Venero Recio, José Luis (Springer, 2023)Parkinson’s Disease (PD) is a neurodegenerative and progressive disorder characterised by intracytoplasmic inclusions ...
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Artículo
Galectin-3, a rising star in modulating microglia activation under conditions of neurodegeneration
García Revilla, Juan; Boza Serrano, Antonio; Espinosa Oliva, Ana María; Sarmiento Soto, Manuel; Deierborg, Tomas; Ruiz Laza, Rocío; Martínez de Pablos, Rocío; Burguillos García, Miguel Ángel; Venero Recio, José Luis (Springer Nature, 2022)The advent of high-throughput single-cell transcriptomic analysis of microglia has revealed different phenotypes that are ...
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Artículo
Galectin‑3, a novel endogenous TREM2 ligand, detrimentally regulates infammatory response in Alzheimer’s disease
Boza Serrano, Antonio; Ruíz Laza, Rocio; Sánchez Varo, Raquel María; García Revilla, Juan; Yang, Yiyi; Jiménez Ferrer, Itzia; Jiménez Muñoz, Sebastián; Roca Ceballos, María Angustias; Navarro Garrido, Victoria; Vitorica Ferrández, Francisco Javier; Venero Recio, José Luis; Deierborg, Tomas (Springer, 2019)Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of ...
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Artículo
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
Shen, Xianli; Burguillos García, Miguel Ángel; Osman, Ahmed Mohamed; Frijhoff, Jeroen; Carrillo Jiménez, Alejandro; Kanatani, Sachie; Augsten, Martin; Saidi, Dalel; Rodhe, Johanna; Kavanagh, Edel T.; Venero Recio, José Luis; Joseph, Bertrand (Springer Nature, 2016-10-19)Glioma cells recruit and exploit microglia (the resident immune cells of the brain) for their proliferation and invasion ...
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Artículo
HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System
Bachiller, Sara; Roca Ceballos, María Angustias; García Domínguez, Irene; Pérez Villegas, Eva María; Martos Carmona, David; Pérez Castro, Miguel Ángel; Real Navarrete, Luis Miguel; Rosa, José Luis; Tabares, Lucía; Venero Recio, José Luis; Armengol, José Ángel; Carrión, Ángel Manuel; Ruiz Laza, Rocío (Springer, 2018-03-30)A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) ...
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Artículo
Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
Gallardo Fernández, Marta; Hornedo Ortega, Ruth; Alonso Bellido, Isabel María; Rodríguez Gómez, José Antonio; Troncoso González, Ana María; García Parrilla, María del Carmen; Venero Recio, José Luis; Espinosa Oliva, Ana María; Martínez de Pablos, Rocío (MDPI, 2020)Neuroinflammation is a common feature shared by neurodegenerative disorders, such as ...
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Artículo
Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider
García Revilla, Juan; Deierborg, Tomas; Venero Recio, José Luis; Boza Serrano, Antonio (Frontiers Media, 2020)COVID-19 disease have become so far the most important sanitary crisis in the XXI century. In light of the events, any ...
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Tesis Doctoral
Implicación de las caspasas-3 y -8 en el trastorno del espectro autista y la enfermedad de Parkinson
García Domínguez, Irene (2020-03-06)El trastorno del espectro autista (TEA) y la enfermedad de Parkinson (EP) son dos desórdenes neurológicos que presentan ...
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Artículo
Inflammatory animal model for parkinson’s disease: the intranigral injection of LPS induced the inflammatory process along with the selective degeneration of nigrostriatal dopaminergic neurons
Machado Quintana, Alberto; Herrera Carmona, Antonio José; Venero Recio, José Luis; Santiago Pavón, Martiniano; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Argüelles Castilla, Sandro; Sarmiento Soto, Manuel; Delgado Cortés, M.J.; Mauriño, R.; Cano, Josefina (A. Conti and A. Lewen, 2011)We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in ...
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Artículo
Inflammatory Animal Models of Parkinson's Disease
García Revilla, Juan; Herrera Carmona, Antonio José; Martínez de Pablos, Rocío; Venero Recio, José Luis (IOS Press, 2022)Accumulating evidence suggests that microglia and peripheral immune cells may play determinant roles in the pathogenesis ...
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Artículo
Inflammatory bowel disease induces pathologicalα-synucleinaggregation in the human gut and brain
Espinosa Oliva, Ana María; Ruiz Laza, Rocío; Sarmiento Soto, Manuel; Boza Serrano, Antonio; Rodríguez Pérez, Ana I; Roca Ceballos, María Angustias; García Revilla, Juan; Santiago Pavón, Martiniano; Carvajal Vázquez, Ana Eloísa; Vázquez Carretero, María Dolores; García Miranda, Pablo; Oliva Martin, María José; Machado Quintana, Alberto; Peral Rubio, María José; Herrera Carmona, Antonio José; Venero Recio, José Luis; Martínez de Pablos, Rocío; neuroinflammation (Wiley, 2024-01-16)Aims According to Braak's hypothesis, it is plausible that Parkinson's disease (PD) originates in the enteric nervous ...
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Artículo
Magnetofection as a new tool to study microglia biology
Venero Recio, José Luis; Burguillos García, Miguel Ángel (Medknow Publications, 2019) -
Artículo
Microglia-secreted galectin-3 acts as a toll-like receptor 4 ligand and contributes to microglial activation
Burguillos García, Miguel Ángel; Svensson, Martina; Schulte, Tim; Boza Serrano, Antonio; García Quintanilla, Alberto; Kavanagh, Edel T.; Santiago Pavón, Martiniano; Viceconte, Nikenza; Oliva Martín, María José; Osman, Ahmed Mohamed; Salomonsson, Emma; Amar, Lahouari; Persson, Annette; Blomgren, Klas; Achour, Adnane; Englund, Elisabet; Leffler, Hakon; Venero Recio, José Luis; Joseph, Bertrand; Deierborg, Tomas (2015)Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory ...
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Artículo
Microglia: Agents of the CNS Pro-Inflammatory Response
Rodríguez Gómez, José Antonio; Kavanagh, Edel T.; Engskog-Vlachos, Pinelopi; Engskog, Mikael; Herrera Carmona, Antonio José; Espinosa Oliva, Ana María; Joseph, Bertrand; Hajji, Nabil; Venero Recio, José Luis; Burguillos García, Miguel Ángel (Multidisciplinary Digital Publishing Institute (MDPI), 2020)The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative ...