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Listar por autor "Bernabé-Caro, Reyes"
Mostrando ítems 1-20 de 22
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Artículo
Addition of Immune Checkpoint Inhibitors to Chemotherapy vs Chemotherapy Alone as First-Line Treatment in Extensive-Stage Small-Cell Lung Carcinoma: A Systematic Review and Meta-Analysis
Arriola, Edurne; González Cao, María; Domine, Manuel; De Castro, Javier; Cobo, Manuel; Bernabé-Caro, Reyes; Isla, Dolores (SPRINGER, 2022)Introduction The addition of immune checkpoint inhibitors (ICIs) to conventional chemotherapy (CT) as first-line treatment ...
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Alectinib after failure to crizotinib in patients with ALK-positive non-small cell lung cancer: results from the Spanish early access program
Bernabé-Caro, Reyes; Garrido, Pilar; García Campelo, Rosario; Palmero, Ramón; Artal, Ángel; Bayona, Cristina; Castro, Javier de (Impact Journals, 2022-06-15)This retrospective observational study analyzed the clinical characteristics, treatment patterns and outcomes of 120 ...
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Blood biomarkers associated to complete pathologicalresponse on NSCLC patients treated with neoadjuvantchemoimmunotherapy included in NADIM clinical trial
Laza-Briviesca, Raquel; Cruz Bermúdez, Alberto; Nadal, Ernest; Insa, Amelia; García Campelo, María del Rosario; Huidobro, Gerardo; Bernabé-Caro, Reyes; Provencio, Mariano (Wiley Open Access, 2021-07-14)Background:Immunotherapy is being tested in early-stage non-small cell lungcancer (NSCLC), and achieving higher rates of ...
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Clinical and molecular parameters associated to pneumonitis development in non-small-cell lung cancer patients receiving chemoimmunotherapy from NADIM trial
Sierra Rodero, Belén; Cruz Bermúdez, Alberto; Nadal, Ernest; Bernabé-Caro, Reyes; Provencio, Mariano (BMC, 2021)Background Pneumonitis (Pn) is one of the main immune-related adverse effects, having a special importance in lung cancer, ...
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Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: results of the RING observational trial
Romero, Atocha; Jantus-Lewintre, Eloisa; García-Peláez, Beatriz; Royuela, Ana.; Insa, Amelia; Bernabé-Caro, Reyes; Provencio, Mariano (Wiley Open Access, 2021-01-04)Several platforms for noninvasive EGFR testing are currently used in the clinical setting with sensitivities ranging from ...
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Correlation of peripheral blood biomarkers with clinical outcomes in NSCLC patients with high PD-L1 expression treated with pembrolizumab
Sánchez-Gastaldo, Amparo; Muñoz-Fuentes, Miguel A.; Molina-Pinelo, Sonia; Alonso-García, Miriam; Boyero, Laura; Bernabé-Caro, Reyes (2021)Background: Immune checkpoint inhibitors (ICIs) are currently the standard therapy in advanced non small cell lung cancer ...
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Cost-effectiveness analysis of molecular diagnosis by next-generation sequencing versus sequential single testing in metastatic non-small cell lung cancer patients from a south Spanish hospital perspective
Álava Casado, Enrique de; Pareja, María Jesús; Carcedo, David; Arrabal, Natalia; García, José-Francisco; Bernabé-Caro, Reyes (Taylor and Francis LTD, 2022)Background: To assess the cost-effectiveness of using next-generation sequencing (NGS) compared to sequential single-testing ...
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Cost-effectiveness of atezolizumab versus pembrolizumab as first-line treatment in PD-L1-positive advanced non-small-cell lung cancer in Spain
Isla, Dolores; Lopez-Brea, Marta; Espinosa, María; Arrabal, Natalia; Pérez-Parente, Diego; Carcedo, David; Bernabé-Caro, Reyes (2023)Background Atezolizumab has recently been approved for first-line treatment of high PD-L1 expression metastatic Non-Small-Cell ...
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Determination of essential biomarkers in lung cancer: a real-world data study in Spain with demographic, clinical, epidemiological and pathological characteristics
Provencio, Mariano; Cobo, Manuel; Rodríguez Abreu, Delvys; Calvo, Virginia; Carcereny, Enric; Cantero, Alexandra; Bernabé-Caro, Reyes; Torrente, Ana (BMC, 2022)Background: The survival of patients with lung cancer has substantially increased in the last decade by about 15%. This ...
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First-Line Nivolumab Plus Ipilimumab in Advanced NSCLC: 4-Year Outcomes From the Randomized, Open-Label, Phase 3 CheckMate 227 Part 1 Trial
Paz Ares, Luis; Ramalingam, Suresh S.; Ciuleanu, Tudor Eliade; Lee, Jong Seok; Urban, Laszlo; Bernabé-Caro, Reyes; Reck, Martin (ELSEVIER SCIENCE INC, 2022)Introduction: In CheckMate 227, nivolumab plus ipilimu mab prolonged overall survival (OS) versus chemotherapy in patients ...
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Impact of smoking status on the relative efficacy of the EGFR TKI/ angiogenesis inhibitor combination therapy in advanced NSCLCda systematic review and meta-analysis
Dafni, U.; Soo, R. A.; Peters, S.; Tsourti, Z.; Zygoura, P.; Vervita, K.; Bernabé-Caro, Reyes; Stahel, R. A. (ESMO open, 2022)Background: The ETOP 10-16 BOOSTER trial failed to demonstrate a progression-free survival (PFS) benefit for adding bevacizumab ...
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Tesis Doctoral
Impacto de la pandemia por SARS-CoV-2 en pacientes con cáncer colorrectal en el área sanitaria del Hospital Universitario Virgen del Rocío y sus distritos de atención sanitaria
Gallego Jiménez, Inmaculada (2023-02-24)Introducción: Desde la irrupción del SARS-CoV-2, la pandemia COVID ha tenido un gran impacto sobre el sistema sanitario, ...
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Metronomic oral vinorelbine in previously untreated advanced non-small-cell lung cancer patients unfit for platinum-based chemotherapy: results of the randomized phase II Tempo Lung trial
Camerini, A.; Morabito, A.; Montanino, A.; Bernabé-Caro, Reyes; Grossi, F.; Kowalski, D. (Elsevier, 2021-02-19)Background: To assess the efficacy and safety of a metronomic schedule of oral vinorelbine (mVNR) in advanced non small-cell ...
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Artículo
Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer (NADIM phase II trial)
Provencio, Mariano; Serna Blasco, Roberto; Nadal, Ernest; Insa, Amelia; García Campelo, M. Rosario; Casal Rubio, Joaquín; Bernabé-Caro, Reyes; Romero, Atocha (AMER SOC CLINICAL ONCOLOGY, 2022)PURPOSE Neoadjuvant chemotherapy plus nivolumab has been shown to be effective in resectable non–small cell lung cancer ...
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Artículo
PD-(L)1 Inhibitors as Monotherapy for the First-Line Treatment of Non-Small-Cell Lung Cancer Patients with High PD-L1 Expression: A Network Meta-Analysis
Majem, Margarita; Cobo, Manuel; Isla, Dolores; Márquez Medina, Diego; Rodríguez Abreu, Delvys; Casal Rubio, Joaquín; Bernabé-Caro, Reyes; Paz-Ares Rodriguez, Luis (MDPI, 2021-03-26)Programmed cell death-ligand 1 (PD-L1) has emerged as a potential biomarker for selection of patients more likely to respond ...
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Artículo
Postnatal Fate of the Ultimobranchial Remnants in the Rat Thyroid Gland
Vázquez Román, María Victoria; Utrilla Alcolea, José Carmelo; Fernández-Santos, José María; Conde Amiano, Esperanza; Bernabé-Caro, Reyes; Sampedro, Consuelo; Martín Lacave, Inés María (Wiley Periodicals, Inc., 2013-07)The ultimobranchial follicles (UBFs) areconsidered embryonic remnants from the ultimobran-chial body (UBB). ...
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Primary and acquired resistance to immunotherapy in lung cancer: unveiling the mechanisms underlying of immune checkpoint blockade therapy
Boyero, Laura; Sanchez-Gastaldo, Amparo; Alonso, Miriam; Noguera Uclés, José Francisco; Molina Pinelo, Sonia; Bernabé-Caro, Reyes (MDPI, 2020-12-11)After several decades without maintained responses or long-term survival of patients with lung cancer, novel therapies ...
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Prognostic model of long-term advanced stage (IIIB-IV) EGFR mutated non-small cell lung cancer (NSCLC) survivors using real-life data
Gutiérrez, Lourdes; Royuela, Ana.; Carcereny, Enric; López Castro, Rafael; Rodríguez Abreu, Delvys; Bernabé-Caro, Reyes; Provencio, Mariano (BMC, 2021-08-31)Background There is a lack of useful diagnostic tools to identify EGFR mutated NSCLC patients with long-term survival. ...
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Real-World Analysis of Nivolumab and Atezolizumab Efficacy in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer
Alonso-García, Miriam; Sánchez-Gastaldo, Amparo; Muñoz-Fuentes, Miguel A.; Molina-Pinelo, Sonia; Boyero, Laura; Benedetti, Johana Cristina; Bernabé-Caro, Reyes (MDPI, 2022)Nivolumab (anti-PD-1 antibody) and atezolizumab (anti-PD-L1 antibody) have shown superior survival outcomes and improved ...
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SEOM-GECP-GETTHI Clinical Guidelines for the treatment of patients with thymic epithelial tumours (2021)
Remón, Jordi; Bernabé-Caro, Reyes; Felip, E.; González Larriba, J.L.; Lázaro, M.; Mielgo Rubio, X; Sánchez, A.; Sullivan, I.; Massuti, B. (SPRINGER, 2022)Thymic epithelial tumours (TET) represent a heterogeneous group of rare malignancies that include thymomas and thymic ...