Data

NameCruz Díaz, Jesús de la
DepartmentGenética
Knowledge areaGenética
Professional categoryCatedrático de Universidad
E-mailRequest
           

  Statistics

  • Items

    41

  • Visits

    3819

  • Downloads

    6134

  Publications

 

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Ubiquitin and Ubiquitin-Like Proteins and Domains in Ribosome Production and Function: Chance or Necessity?

Martín Villanueva, Sara; Gutiérrez Pozo, Gabriel; Kressler, Dieter; Cruz Díaz, Jesús de la (Multidisciplinary Digital Publishing Institute (MDPI), 2021-01-01)
Ubiquitin is a small protein that is highly conserved throughout eukaryotes. It operates as a reversible post-translational ...
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A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae

Rodríguez Galán, Olga; García Gómez, Juan José; Valle Rosado, Iván; Wei, Wu; Méndez-Godoy, Alfonso; Pillet, Benjamin; Alekseenko, Alisa; Steinmetz, Lars M.; Pelechano, Vicent; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2021-01-01)
Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid ...
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Association of snR190 snoRNA chaperone with early pre-60S particles is regulated by the RNA helicase Dbp7 in yeast

Jaafar, Mariam; Contreras Fernández, Julia Mª; Dominique, Carine; Martín Villanueva, Sara; Capeyrou, Régine; Vitali, Patrice; Rodríguez Galán, Olga; Velasco Ramírez, María del Carmen; Humbert, Odile; Watkins, Nicholas J.; Villalobo Polo, Eduardo; Bohnsack, Katherine E.; Cruz Díaz, Jesús de la; Henras, Anthony K. (Springer Nature, 2021-01-01)
Synthesis of eukaryotic ribosomes involves the assembly and maturation of precursor particles (pre-ribosomal particles) ...
PhD Thesis
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RNA Helicases in 60S Ribosomal Subunit Biogenesis in Saccharomyces cerevisiae

Villalobo Polo, Eduardo; Cruz Díaz, Jesús de la; Contreras Fernández, Julia Mª (2020-11-10)
The ribosomes are the cellular organelles responsible for translating messenger RNA (mRNA) to proteins. In eukaryotic ...
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Molecular Pathways Leading to Induction of Cell Death and Anti-Proliferative Properties by Tacrolimus and mTOR Inhibitors in Liver Cancer Cells

Navarro Villarán, Elena; Cruz Ojeda, Patricia de la; Contreras, Laura; González, Raul; Negrete, María; Rodríguez Hernández, María A.; Marín Gómez, Luis Miguel; Álamo Martínez, José M.; Calvo, Antonio; Gómez Bravo, Miguel Ángel; Cruz Díaz, Jesús de la; Padillo Ruiz, Francisco Javier; Muntané Relat, Jordi (1421-9778, 2020-01-01)
Background/Aims: Orthotopic liver transplantation (OLT) is the recommended treatment for patients at early stages of ...
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The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes

Olombrada, Miriam; Pena, Cohue; Rodríguez Galán, Olga; Klingauf Nerurkar, Purnima; Portugal Calisto, Daniela; Oborska Oplová, Michaela; Altvater, Martín; Gavilanes, Jose G.; Martínez del Pozo, Álvaro; Cruz Díaz, Jesús de la (Oxford University Press, 2020-01-01)
The ribotoxin α-sarcin belongs to a family of ribonucleases that cleave the sarcin/ricin loop (SRL), a critical functional ...
PhD Thesis
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Role of ribosomal proteins eL40 and eS12 in the biogenesis and function of yeast ribosomes

Cruz Díaz, Jesús de la; Martín Villanueva, Sara (2019-10-11)
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The Ubiquitin Moiety of Ubi1 Is Required for Productive Expression of Ribosomal Protein eL40 in Saccharomyces cerevisiae

Martín Villanueva, Sara; Fernández Pevida, Antonio; Kressler, Dieter; Cruz Díaz, Jesús de la (MDPI, 2019-01-01)
Ubiquitin is a highly conserved small eukaryotic protein. It is generated by proteolytic cleavage of precursor proteins ...
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Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae

Espinar Marchena, Francisco José; Rodríguez Galán, Olga; Fernández Fernández, José; Linnemann, Jan; Cruz Díaz, Jesús de la (Oxford University Press, 2018-01-01)
The contribution of most ribosomal proteins to ribo- some synthesis has been quite well analysed in Sac- charomyces ...
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Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells

Rodríguez Hernández, María A.; González, Raúl; Rosa, Ángel J. de la; Gallego, Paloma; Ordóñez, Raquel; Navarro Villarán, Elena; Contreras Bernal, Laura; Rodríguez Arribas, M.; Cruz Díaz, Jesús de la (Wiley-Blackwell, 2018-01-01)
Sorafenib is the unique accepted molecular targeted drug for the treatment of patients in advanced stage of hepatocellular ...
PhD Thesis
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Estudio del ensamblaje ribosómico en Saccharomyces Cerevisae.

Cruz Díaz, Jesús de la; Espinar Marchena, Francisco José (2017-09-15)
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Placeholder factors in ribosome biogenesis: please, pave my way

Espinar Marchena, Francisco José; Babiano González, Reyes; Cruz Díaz, Jesús de la (Shared Science Publishers, 2017-01-01)
The synthesis of cytoplasmic eukaryotic ribosomes is an extraordinarily energy-demanding cellular activity that occurs ...
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The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation

Gómez Herreros, Fernando; Margaritis, Thanasis; Rodríguez Galán, Olga; Pelechano, Vicent; Begley, Victoria Sarah; Millán Zambrano, Gonzalo; Morillo Huesca, Macarena; Muñoz Centeno, María de la Cruz; Pérez Ortín, José Enrique; Cruz Díaz, Jesús de la; Holstege, Frank C.P.; Chávez de Diego, Sebastián (Oxford University Press, 2017-01-01)
Ribosome assembly requires the concerted expression of hundreds of genes, which are transcribed by all three nuclear RNA ...
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The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits

Fernández Pevida, Antonio; Martín Villanueva, Sara; Murat, Guillaume; Lacombe, Thierry; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2016-01-01)
The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes ...
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The dedicated chaperone acl4 escorts ribosomal protein rpl4 to its nuclear pre-60s assembly site

Pillet, Benjamin; García Gómez, Juan José; Pausch, Patrick; Falquet, Laurent; Bange, Gert; Cruz Díaz, Jesús de la; Kressler, Dieter (Public Library of Science, 2015-01-01)
Ribosomes are the highly complex macromolecular assemblies dedicated to the synthesis of all cellular proteins from mRNA ...
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The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two β-propellers during the assembly of large ribosomal subunits in eukaryotes

Wegreck, Marcin; Rodríguez Galán, Olga; Cruz Díaz, Jesús de la; Bravo, Jerónimo (Oxford University Press, 2015-01-01)
Ribosome biogenesis is one of the most essential pathways in eukaryotes although it is still not fully characterized. Given ...
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The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription

Mirón García, María Carmen; Garrido Godino, Ana Isabel; Martínez Fernández, Verónica; Fernández Pevida, Antonio; Cuevas Bermúdez, Abel; Martín Expósito, Manuel; Chávez de Diego, Sebastián; Cruz Díaz, Jesús de la; Navarro, Francisco (Oxford University Press, 2014-01-01)
Bud27, the yeast orthologue of human URI/RMP, is a member of the prefoldin-like family of ATPindependent molecular chaperones. ...
PhD Thesis
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Role of ubiquitin fusion ribosomal proteins in the synthesis and function of yeast ribosomes

Cruz Díaz, Jesús de la; Fernández Pevida, Antonio (2014-01-01)
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Final pre-40s maturation depends on the functional integrity of the 60s subunit ribosomal protein l3

García Gómez, Juan José; Fernández Pevida, Antonio; Lebaron, Simon; Valle Rosado, Iván; Tollervey, David W.; Kressler, Dieter; Cruz Díaz, Jesús de la (Public Library of Science, 2014-01-01)
Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. ...
PhD Thesis
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Estudio funcional de proteínas ribosómicas durante la biogénesis de ribosomas en saccharomyces cerevisiae

Cruz Díaz, Jesús de la; Babiano González, Reyes (2013-07-12)
En el Capítulo I de esta tesis se muestran los resultados de la caracterización funcional de la proteína ribosómica L35, ...
PhD Thesis
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Análisis funcional de factores de actuación en trans y proteínas ribosómicas durante la síntesis de subunidades ribosómicas en Saccharomyces cerevisiae

Cruz Díaz, Jesús de la; García Gómez, Juan José (2013-01-18)
El estudio de la síntesis de los ribosomas eucariotas es un campo de investigación muy prolífico debido, sin duda, a la ...
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Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles

Saveanu, Cosmin; Babiano González, Reyes; Badis, Gwenael; Díaz Quintana, Antonio Jesús; Cruz Díaz, Jesús de la; Doyen, Antonia; Fromont Racine, Micheline; Jacquier, Alain; Namame, Abdelkader; Saveanu, Cosmin (2013-01-01)
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Balanced production of ribosome components is required for proper G/S transition in saccharomyces cerevisiae

Gómez Herreros, Fernando; Rodríguez Galán, Olga; Morillo Huesca, Macarena; Maya, Douglas; Arista Romero, María; Cruz Díaz, Jesús de la; Chávez de Diego, Sebastián; Muñoz Centeno, María de la Cruz (American Society for Biochemistry and Molecular Biology Inc., 2013-01-01)
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Yeast Polypeptide Exit Tunnel Ribosomal Proteins L17, L35, and L37 are Necessary to Recruit Late-assembling Factors Required for 27SB Pre-rRNA Processing

Woolford, John L.; Babiano González, Reyes; Cruz Díaz, Jesús de la; Gamalinda, Michael; Jakovljevic, Jelena; Talkish, Jason (2013-01-01)
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Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function

Babiano González, Reyes; Gamalinda, Michael; Woolford, John L.; Cruz Díaz, Jesús de la (American Society for Microbiology, 2012-01-01)
Ribosomal proteins play important roles in ribosome biogenesis and function. Here, we study the evolutionarily conserved ...
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Dynamics of the putative RNA helicase spb4 during ribosome assembly insaccharomyces cerevisiae

García Gómez, Juan José; Lebaron, Simon; Froment, Carine; Monsarrat, Bernard; Henry, Yves; Cruz Díaz, Jesús de la (American Society for Microbiology, 2011-01-01)
Spb4 is a putative ATP-dependent RNA helicase that is required for proper processing of 27SB pre-rRNAs and therefore for ...
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Nab2 functions in the metabolism of RNA driven by polymerases II and III

González Aguilera, Cristina; Tous, Cristina; Babiano González, Reyes; Cruz Díaz, Jesús de la; Luna Varo, Rosa María; Aguilera López, Andrés (American Society for Cell Biology, 2011-01-01)
Gene expression in eukaryotes is an essential process that includes transcription, RNA processing, and export. One ...
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Ribosomal protein L35 is required for 27SB pre-rRNA processing in Saccharomyces cerevisiae

Babiano González, Reyes; Cruz Díaz, Jesús de la (2010-01-01)
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The amino terminal domain from Mrt4 protein can functionally replace the RNA binding domain of the ribosomal P0 protein

Santos, C.; Abia, David; Ballesta, Juan Pedro G.; Cruz Díaz, Jesús de la; García Gómez, Juan José; Morreale, Antonio; Remacha, Miguel; Rodríguez Mateos, M. (2009-01-01)
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Role and dynamics of the ribosomal protein p0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae

Remacha, Miguel; Cruz Díaz, Jesús de la; García Gómez, Juan José; Ballesta, Juan Pedro G.; Francisco Velilla, Rosario; Francisco Velilla, Rosario (2009-01-01)
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Characterization of saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis

Rosado, Iván; Dez, Christophe; Lebaron, Simon; Caizergues-Ferrer, Michèle; Henry, Yves; Cruz Díaz, Jesús de la (American Society for Microbiology, 2007-01-01)
We report the characterization of the yeast Npa2p (Urb2p) protein, which is essential for 60S ribosomal subunit biogenesis. ...
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Functional analysis of saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis

Valle Rosado, Iván; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2007-01-01)
Ribosome synthesis in eukaryotes requires a multitude oftrans-acting factors. These factors act at many steps as the ...
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The essential WD-repeat protein Rsa4p is required for rRNA processing and intra-nuclear transport of 60S ribosomal subunits

Cruz Díaz, Jesús de la; Sanz Martínez, Eloisa; Remacha, Miguel (Oxford University Press, 2005-01-01)
We report the characterization of a novel factor, Rsa4p (Ycr072cp), which is essential for the synthesis of 60S ribosomal ...
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An Antifungal Exo-alpha 1,3-Glucanase (AGN13.1) from the Biocontrol Fungus Trichoderma harzianum

Ait Lahsen, Hassane; Soler, Andrés; Rey, Manuel; Cruz Díaz, Jesús de la; Monte, Enrique; Llobell González, Antonio (American Society for Microbiology, 2001-01-01)
Trichoderma harzianum secretes α-1,3-glucanases when it is grown on polysaccharides, fungal cell walls, or autoclaved ...
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Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae

Kressler, Dieter; Linder, Patrick; Cruz Díaz, Jesús de la (American Society for Microbiology, 1999-01-01)
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Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae

Kressler, Dieter; Rojo, Manuel; Linder, Patrick; Cruz Díaz, Jesús de la (Oxford University Press, 1999-01-01)
Several mutants (spb1-spb7) have been previously identified as cold-sensitive extragenic suppressors of loss-of-function ...
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Dbp6p is an essential putative ATP-dependent RNA helicase required for 60S-ribosomal-subunit assembly in Saccharomyces cerevisiae

Kressler, Dieter; Cruz Díaz, Jesús de la; Rojo, Manuel; Linder, Patrick (American Society for Microbiology, 1998-01-01)
A previously uncharacterizedSaccharomyces cerevisiaeopen reading frame, YNR038W, was analyzed in the context of the European ...
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Fal1p is an essential DEAD-box protein involved in 40S-ribosomal- subunit biogenesis in saccharomyces cerevisiae

Kressler, Dieter; Cruz Díaz, Jesús de la; Rojo, Manuel; Linder, Patrick (American Society for Microbiology, 1997-01-01)
A previously uncharacterizedSaccharomyces cerevisiaegene,FAL1, was found by sequence comparison as a homolog of the ...
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A novel endo-β-1,3-glucanase, BGN13.1, involved in the mycoparasitism of Trichoderma harzianum

Cruz Díaz, Jesús de la; Pintor Toro, José Antonio; Benítez Fernández, Concepción Tahía; Llobell González, Antonio; Romero González, Luis Carlos (American Society for Microbiology, 1995-01-01)
The mycoparasitic fungus Trichoderma harzianum CECT 2413 produces at least three extracellular β-1,3-glucanases. The most ...
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Purification and characterization of an endo-beta-1,6-glucanase from Trichoderma harzianum that is related to its mycoparasitism

Cruz Díaz, Jesús de la; Pintor Toro, José Antonio; Benítez Fernández, Concepción Tahía; Llobell González, Antonio (American Society for Microbiology, 1995-01-01)
he enzymes from Trichoderma species that degrade fungal cell walls have been suggested to play an important role in ...
PhD Thesis
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Purificación y caracterización de hidrolasas implicadas en el microparasitismo de Trichoderma harzianum

Benítez Fernández, Concepción Tahía; Llobell González, Antonio; Cruz Díaz, Jesús de la (1994-01-01)
Los hongos del genero Trichoderma son buenos agentes de control biológico. Entre los mecanismos que estos utilizan para ...