idUS - Perfil del autor: Cruz Díaz, Jesús de la

Nombre	Cruz Díaz, Jesús de la
Departamento	Genética
Área de conocimiento	Genética
Categoría profesional	Catedrático de Universidad
Correo electrónico	Solicitar

Nº publicaciones

56
Nº visitas

7288
Nº descargas

13168

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Publicaciones
Tesis Doctoral Study of Pol5 protein from Saccharomyces cerevisiae and its human ortholog MYBBP1A in ribosome biogenesis Ramos Sáenz, Ana; Cruz Díaz, Jesús de la (2024) Los ribosomas son los orgánulos celulares que llevan a cabo el llamado proceso de traducción, en el cual las proteínas se ...
Tesis Doctoral Molecular description of the role of protein synthesis in the cellular response to the treatment with the antitumoral drug Sorafenib in HCC lines Contreras Bernal, Laura; Cruz Díaz, Jesús de la; Muntané Relat, Jordi (2023) El carcinoma hepatocellular (CHC) es reconocido como el principal cáncer primario de hígado y uno de los cánceres con mayor ...
Tesis Doctoral eL15 and eL22 proteins and their functional environments during ribosome assembly in Saccharomyces cerevisiae Fernández Fernández, José; Cruz Díaz, Jesús de la (2023) Ribosomes are ribonucleoprotein complexes in charge of protein translation. Translation is an essential process in all ...
Artículo The Terminal Extensions of Dbp7 Influence Growth and 60S Ribosomal Subunit Biogenesis in Saccharomyces cerevisiae Contreras Fernández, Julia Mª; Ruiz Blanco, Óscar; Dominique, Carine; Humbert, Odile; Henry, Yves; Henras, Anthony K.; Cruz Díaz, Jesús de la; Villalobo Polo, Eduardo (Multidisciplinary Digital Publishing Institute (MDPI), 2023) Ribosome synthesis is a complex process that involves a large set of protein trans-acting factors, among them DEx(D/H)-box ...
Artículo Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation Micic, Jelena; Rodríguez Galán, Olga; Babiano González, Reyes; Fitzgerald, Fiona; Fernández Fernández, José; Gao, Ning; Woolford, John L.; Cruz Díaz, Jesús de la (Oxford University Press, 2022) During translation, nascent polypeptide chains travel from the peptidyl transferase center through the nascent polypeptide ...
Artículo Broad Transcriptomic Impact of Sorafenib and Its Relation to the Antitumoral Properties in Liver Cancer Cells Contreras Bernal, Laura; Rodríguez Gil, Alfonso; Muntané Relat, Jordi; Cruz Díaz, Jesús de la (Multidisciplinary Digital Publishing Institute (MDPI), 2022) Hepatocellular carcinoma (HCC) is one of the most frequent and essentially incurable cancers in its advanced stages. The ...
Artículo The C-terminal tail of ribosomal protein Rps15 is engaged in cytoplasmic pre-40S maturation Rossler, Ingrid; Weigl, Sarah; Fernández Fernández, José; Martín Villanueva, Sara; Strauss, Daniela; Hurt, Ed; Cruz Díaz, Jesús de la; Pertschy, Brigitte (Taylor & Francis, 2022) The small ribosomal subunit protein Rps15/uS19 is involved in early nucleolar ribosome biogenesis and subsequent nuclear ...
Artículo Ubiquitin and Ubiquitin-Like Proteins and Domains in Ribosome Production and Function: Chance or Necessity? Martín Villanueva, Sara; Gutiérrez Pozo, Gabriel; Kressler, Dieter; Cruz Díaz, Jesús de la (Multidisciplinary Digital Publishing Institute (MDPI), 2021) Ubiquitin is a small protein that is highly conserved throughout eukaryotes. It operates as a reversible post-translational ...
Artículo A functional connection between translation elongation and protein folding at the ribosome exit tunnel in Saccharomyces cerevisiae Rodríguez Galán, Olga; García Gómez, Juan José; Valle Rosado, Iván; Wei, Wu; Méndez-Godoy, Alfonso; Pillet, Benjamin; Alekseenko, Alisa; Steinmetz, Lars M.; Pelechano, Vicent; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2021) Proteostasis needs to be tightly controlled to meet the cellular demand for correctly de novo folded proteins and to avoid ...
Artículo Association of snR190 snoRNA chaperone with early pre-60S particles is regulated by the RNA helicase Dbp7 in yeast Jaafar, Mariam; Contreras Fernández, Julia Mª; Dominique, Carine; Martín Villanueva, Sara; Capeyrou, Régine; Vitali, Patrice; Rodríguez Galán, Olga; Velasco Ramírez, María del Carmen; Humbert, Odile; Watkins, Nicholas J.; Villalobo Polo, Eduardo; Bohnsack, Katherine E.; Cruz Díaz, Jesús de la; Henras, Anthony K. (Springer Nature, 2021) Synthesis of eukaryotic ribosomes involves the assembly and maturation of precursor particles (pre-ribosomal particles) ...
Tesis Doctoral RNA Helicases in 60S Ribosomal Subunit Biogenesis in Saccharomyces cerevisiae Contreras Fernández, Julia Mª; Villalobo Polo, Eduardo; Cruz Díaz, Jesús de la (2020) The ribosomes are the cellular organelles responsible for translating messenger RNA (mRNA) to proteins. In eukaryotic ...
Artículo Prefoldin-like Bud27 influences the transcription of ribosomal components and ribosome biogenesis in Saccharomyces cerevisiae Martínez Fernández, Verónica; Cuevas Bermúdez, Abel; Gutiérrez Santiago, Francisco; Garrido Godino, Ana Isabel; Rodríguez Galán, Olga; Jordán Pla, Antonio; Lois, Sergio; Triviño, Juan C.; Cruz Díaz, Jesús de la; Navarro, Francisco (Cold Spring Harbor Laboratory Press, 2020) Understanding the functional connection that occurs for the three nuclear RNA polymerases to synthesize ribosome components ...
Artículo Molecular Pathways Leading to Induction of Cell Death and Anti-Proliferative Properties by Tacrolimus and mTOR Inhibitors in Liver Cancer Cells Navarro Villarán, Elena; Cruz Ojeda, Patricia de la; Contreras, Laura; González, Raul; Negrete, María; Rodríguez Hernández, María A.; Marín Gómez, Luis Miguel; Álamo Martínez, José M.; Calvo, Antonio; Gómez Bravo, Miguel Ángel; Cruz Díaz, Jesús de la; Padillo Ruiz, Francisco Javier; Muntané Relat, Jordi (1421-9778, 2020) Background/Aims: Orthotopic liver transplantation (OLT) is the recommended treatment for patients at early stages of ...
Artículo Overexpression of budding yeast protein phosphatase Ppz1 impairs translation Calafí Pascual, Carlos Alberto; López Malo, María; Velázquez, Diego; Zhang, Chunyi; Fernández Fernández, José; Rodríguez Galán, Olga; Cruz Díaz, Jesús de la (Elsevier, 2020) The Ser/Thr protein phosphatase Ppz1 from Saccharomyces cerevisiae is the best characterized member of a family of enzymes ...
Artículo The ribotoxin α-sarcin can cleave the sarcin/ricin loop on late 60S pre-ribosomes Olombrada, Miriam; Pena, Cohue; Rodríguez Galán, Olga; Klingauf Nerurkar, Purnima; Portugal Calisto, Daniela; Oborska Oplová, Michaela; Altvater, Martín; Gavilanes, Jose G.; Martínez del Pozo, Álvaro; Cruz Díaz, Jesús de la (Oxford University Press, 2020) The ribotoxin α-sarcin belongs to a family of ribonucleases that cleave the sarcin/ricin loop (SRL), a critical functional ...
Tesis Doctoral Role of ribosomal proteins eL40 and eS12 in the biogenesis and function of yeast ribosomes Martín Villanueva, Sara; Cruz Díaz, Jesús de la (2019)
Artículo Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae Ramos Sáenz, Ana; González Álvarez, Daniel; Rodríguez Galán, Olga; Rodríguez Gil, Alfonso; Gaspar, Sonia G.; Villalobo Polo, Eduardo; Dosil, Mercedes; Cruz Díaz, Jesús de la (Cold Spring Harbor Laboratory Press, 2019) In Saccharomyces cerevisiae, more than 250 trans-acting factors are involved in the maturation of 40S and 60S ribosomal ...
Artículo The Ubiquitin Moiety of Ubi1 Is Required for Productive Expression of Ribosomal Protein eL40 in Saccharomyces cerevisiae Martín Villanueva, Sara; Fernández Pevida, Antonio; Kressler, Dieter; Cruz Díaz, Jesús de la (MDPI, 2019) Ubiquitin is a highly conserved small eukaryotic protein. It is generated by proteolytic cleavage of precursor proteins ...
Artículo Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae Espinar Marchena, Francisco José; Rodríguez Galán, Olga; Fernández Fernández, José; Linnemann, Jan; Cruz Díaz, Jesús de la (Oxford University Press, 2018) The contribution of most ribosomal proteins to ribo- some synthesis has been quite well analysed in Sac- charomyces ...
Artículo Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells Rodríguez Hernández, María A.; González, Raúl; Rosa, Ángel J. de la; Gallego, Paloma; Ordóñez, Raquel; Navarro Villarán, Elena; Contreras Bernal, Laura; Rodríguez Arribas, M.; Cruz Díaz, Jesús de la (Wiley-Blackwell, 2018) Sorafenib is the unique accepted molecular targeted drug for the treatment of patients in advanced stage of hepatocellular ...
Tesis Doctoral Estudio del ensamblaje ribosómico en Saccharomyces Cerevisae. Espinar Marchena, Francisco José; Cruz Díaz, Jesús de la (2017)
Artículo The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation Gómez Herreros, Fernando; Margaritis, Thanasis; Rodríguez Galán, Olga; Pelechano, Vicent; Begley, Victoria Sarah; Millán Zambrano, Gonzalo; Morillo Huesca, Macarena; Muñoz Centeno, María de la Cruz; Pérez Ortín, José Enrique; Cruz Díaz, Jesús de la; Holstege, Frank C.P.; Chávez de Diego, Sebastián (Oxford University Press, 2017) Ribosome assembly requires the concerted expression of hundreds of genes, which are transcribed by all three nuclear RNA ...
Artículo Placeholder factors in ribosome biogenesis: please, pave my way Espinar Marchena, Francisco José; Babiano González, Reyes; Cruz Díaz, Jesús de la (Shared Science Publishers, 2017) The synthesis of cytoplasmic eukaryotic ribosomes is an extraordinarily energy-demanding cellular activity that occurs ...
Artículo The eukaryote-specific N-terminal extension of ribosomal protein S31 contributes to the assembly and function of 40S ribosomal subunits Fernández Pevida, Antonio; Martín Villanueva, Sara; Murat, Guillaume; Lacombe, Thierry; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2016) The archaea-/eukaryote-specific 40S-ribosomal-subunit protein S31 is expressed as an ubiquitin fusion protein in eukaryotes ...
Artículo The structure of Erb1-Ytm1 complex reveals the functional importance of a high-affinity binding between two β-propellers during the assembly of large ribosomal subunits in eukaryotes Wegreck, Marcin; Rodríguez Galán, Olga; Cruz Díaz, Jesús de la; Bravo, Jerónimo (Oxford University Press, 2015) Ribosome biogenesis is one of the most essential pathways in eukaryotes although it is still not fully characterized. Given ...
Artículo The dedicated chaperone acl4 escorts ribosomal protein rpl4 to its nuclear pre-60s assembly site Pillet, Benjamin; García Gómez, Juan José; Pausch, Patrick; Falquet, Laurent; Bange, Gert; Cruz Díaz, Jesús de la; Kressler, Dieter (Public Library of Science, 2015) Ribosomes are the highly complex macromolecular assemblies dedicated to the synthesis of all cellular proteins from mRNA ...
Artículo Final pre-40s maturation depends on the functional integrity of the 60s subunit ribosomal protein l3 García Gómez, Juan José; Fernández Pevida, Antonio; Lebaron, Simon; Valle Rosado, Iván; Tollervey, David W.; Kressler, Dieter; Cruz Díaz, Jesús de la (Public Library of Science, 2014) Ribosomal protein L3 is an evolutionarily conserved protein that participates in the assembly of early pre-60S particles. ...
Tesis Doctoral Role of ubiquitin fusion ribosomal proteins in the synthesis and function of yeast ribosomes Fernández Pevida, Antonio; Cruz Díaz, Jesús de la (2014)
Artículo The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription Mirón García, María Carmen; Garrido Godino, Ana Isabel; Martínez Fernández, Verónica; Fernández Pevida, Antonio; Cuevas Bermúdez, Abel; Martín Expósito, Manuel; Chávez de Diego, Sebastián; Cruz Díaz, Jesús de la; Navarro, Francisco (Oxford University Press, 2014) Bud27, the yeast orthologue of human URI/RMP, is a member of the prefoldin-like family of ATPindependent molecular chaperones. ...
Tesis Doctoral Estudio funcional de proteínas ribosómicas durante la biogénesis de ribosomas en saccharomyces cerevisiae Babiano González, Reyes; Cruz Díaz, Jesús de la (2013) En el Capítulo I de esta tesis se muestran los resultados de la caracterización funcional de la proteína ribosómica L35, ...
Tesis Doctoral Análisis funcional de factores de actuación en trans y proteínas ribosómicas durante la síntesis de subunidades ribosómicas en Saccharomyces cerevisiae García Gómez, Juan José; Cruz Díaz, Jesús de la (2013) El estudio de la síntesis de los ribosomas eucariotas es un campo de investigación muy prolífico debido, sin duda, a la ...
Artículo Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles Saveanu, Cosmin; Babiano González, Reyes; Badis, Gwenael; Díaz Quintana, Antonio Jesús; Cruz Díaz, Jesús de la; Doyen, Antonia; Fromont Racine, Micheline; Jacquier, Alain; Namame, Abdelkader; Saveanu, Cosmin (2013)
Artículo Balanced production of ribosome components is required for proper G/S transition in saccharomyces cerevisiae Gómez Herreros, Fernando; Rodríguez Galán, Olga; Morillo Huesca, Macarena; Maya, Douglas; Arista Romero, María; Cruz Díaz, Jesús de la; Chávez de Diego, Sebastián; Muñoz Centeno, María de la Cruz (American Society for Biochemistry and Molecular Biology Inc., 2013)
Artículo Yeast Polypeptide Exit Tunnel Ribosomal Proteins L17, L35, and L37 are Necessary to Recruit Late-assembling Factors Required for 27SB Pre-rRNA Processing Woolford, John L.; Babiano González, Reyes; Cruz Díaz, Jesús de la; Gamalinda, Michael; Jakovljevic, Jelena; Talkish, Jason (2013)
Artículo Yeast ribosomal protein L40 assembles late into precursor 60 S ribosomes and is required for their cytoplasmic maturation Fernández Pevida, Antonio; Rodríguez Galán, Olga; Díaz Quintana, Antonio Jesús; Kressler, Dieter; Cruz Díaz, Jesús de la (Elsevier, 2012) Background: The contribution of ribosomal proteins to ribosome assembly and function is often not well understood. Results: ...
Artículo Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function Babiano González, Reyes; Gamalinda, Michael; Woolford, John L.; Cruz Díaz, Jesús de la (American Society for Microbiology, 2012) Ribosomal proteins play important roles in ribosome biogenesis and function. Here, we study the evolutionarily conserved ...
Artículo Nab2 functions in the metabolism of RNA driven by polymerases II and III González Aguilera, Cristina; Tous, Cristina; Babiano González, Reyes; Cruz Díaz, Jesús de la; Luna Varo, Rosa María; Aguilera López, Andrés (American Society for Cell Biology, 2011) Gene expression in eukaryotes is an essential process that includes transcription, RNA processing, and export. One ...
Artículo Dynamics of the putative RNA helicase spb4 during ribosome assembly insaccharomyces cerevisiae García Gómez, Juan José; Lebaron, Simon; Froment, Carine; Monsarrat, Bernard; Henry, Yves; Cruz Díaz, Jesús de la (American Society for Microbiology, 2011) Spb4 is a putative ATP-dependent RNA helicase that is required for proper processing of 27SB pre-rRNAs and therefore for ...
Artículo Ribosomal protein L35 is required for 27SB pre-rRNA processing in Saccharomyces cerevisiae Babiano González, Reyes; Cruz Díaz, Jesús de la (2010)
Artículo Role and dynamics of the ribosomal protein p0 and its related trans-acting factor Mrt4 during ribosome assembly in Saccharomyces cerevisiae Remacha, Miguel; Cruz Díaz, Jesús de la; García Gómez, Juan José; Ballesta, Juan Pedro G.; Francisco Velilla, Rosario; Francisco Velilla, Rosario (2009)
Artículo The amino terminal domain from Mrt4 protein can functionally replace the RNA binding domain of the ribosomal P0 protein Santos, C.; Abia, David; Ballesta, Juan Pedro G.; Cruz Díaz, Jesús de la; García Gómez, Juan José; Morreale, Antonio; Remacha, Miguel; Rodríguez Mateos, M. (2009)
Artículo Functional analysis of saccharomyces cerevisiae ribosomal protein Rpl3p in ribosome synthesis Valle Rosado, Iván; Kressler, Dieter; Cruz Díaz, Jesús de la (Oxford University Press, 2007) Ribosome synthesis in eukaryotes requires a multitude oftrans-acting factors. These factors act at many steps as the ...
Artículo Characterization of saccharomyces cerevisiae Npa2p (Urb2p) reveals a low-molecular-mass complex containing Dbp6p, Npa1p (Urb1p), Nop8p, and Rsa3p involved in early steps of 60S ribosomal subunit biogenesis Rosado, Iván; Dez, Christophe; Lebaron, Simon; Caizergues-Ferrer, Michèle; Henry, Yves; Cruz Díaz, Jesús de la (American Society for Microbiology, 2007) We report the characterization of the yeast Npa2p (Urb2p) protein, which is essential for 60S ribosomal subunit biogenesis. ...
Artículo The essential WD-repeat protein Rsa4p is required for rRNA processing and intra-nuclear transport of 60S ribosomal subunits Cruz Díaz, Jesús de la; Sanz Martínez, Eloisa; Remacha, Miguel (Oxford University Press, 2005) We report the characterization of a novel factor, Rsa4p (Ycr072cp), which is essential for the synthesis of 60S ribosomal ...
Artículo Npa1p is an essential trans-acting factor required for an early step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae Valle Rosado, Iván; Cruz Díaz, Jesús de la (Cold Spring Harbor Laboratory Press, 2004) Ribosome biogenesis requires > 100 nonribosomal proteins, which are associated with different preribosomal particles. The ...
Patente. Invención Proteína con actividad antifúngica Rey Barrera, Manuel; Soler Castells, Andrés; Ait Lahsen, Hassane; Cruz Díaz, Jesús de la; Monte Vázquez, Enrique; Llobell González, Antonio (Oficina Española de Patentes y Marcas (OEPM), 2003) Proteína con actividad antifúngica. Esta invención se refiere a una proteína con actividad antifúngica que posee, además, ...
Artículo Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA Cruz Díaz, Jesús de la; Vioque Peña, Agustín (Cold Spring Harbor Laboratory Press, 2001) tmRNA (also known as SsrA or 10Sa RNA) is involved in a trans-translation reaction that contributes to the recycling of ...
Artículo An Antifungal Exo-alpha 1,3-Glucanase (AGN13.1) from the Biocontrol Fungus Trichoderma harzianum Ait Lahsen, Hassane; Soler, Andrés; Rey, Manuel; Cruz Díaz, Jesús de la; Monte, Enrique; Llobell González, Antonio (American Society for Microbiology, 2001) Trichoderma harzianum secretes α-1,3-glucanases when it is grown on polysaccharides, fungal cell walls, or autoclaved ...
Artículo Spb1p is a putative methyltransferase required for 60S ribosomal subunit biogenesis in Saccharomyces cerevisiae Kressler, Dieter; Rojo, Manuel; Linder, Patrick; Cruz Díaz, Jesús de la (Oxford University Press, 1999) Several mutants (spb1-spb7) have been previously identified as cold-sensitive extragenic suppressors of loss-of-function ...
Artículo Protein trans-acting factors involved in ribosome biogenesis in Saccharomyces cerevisiae Kressler, Dieter; Linder, Patrick; Cruz Díaz, Jesús de la (American Society for Microbiology, 1999)
Artículo Dbp6p is an essential putative ATP-dependent RNA helicase required for 60S-ribosomal-subunit assembly in Saccharomyces cerevisiae Kressler, Dieter; Cruz Díaz, Jesús de la; Rojo, Manuel; Linder, Patrick (American Society for Microbiology, 1998) A previously uncharacterizedSaccharomyces cerevisiaeopen reading frame, YNR038W, was analyzed in the context of the European ...
Artículo Spb4p, an essential putative RNA helicase, is required for a late step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae Cruz Díaz, Jesús de la; Kressler, Dieter; Rojo, Manuel; Tollervey, David W.; Linder, Patrick (Cold Spring Harbor Laboratory Press, 1998) Spb4p is a putative ATP-dependent RNA helicase that is required for synthesis of 60S ribosomal subunits. Polysome analyses ...
Artículo Fal1p is an essential DEAD-box protein involved in 40S-ribosomal- subunit biogenesis in saccharomyces cerevisiae Kressler, Dieter; Cruz Díaz, Jesús de la; Rojo, Manuel; Linder, Patrick (American Society for Microbiology, 1997) A previously uncharacterizedSaccharomyces cerevisiaegene,FAL1, was found by sequence comparison as a homolog of the ...
Artículo Purification and characterization of an endo-beta-1,6-glucanase from Trichoderma harzianum that is related to its mycoparasitism Cruz Díaz, Jesús de la; Pintor Toro, José Antonio; Benítez Fernández, Concepción Tahía; Llobell González, Antonio (American Society for Microbiology, 1995) he enzymes from Trichoderma species that degrade fungal cell walls have been suggested to play an important role in ...
Artículo A novel endo-β-1,3-glucanase, BGN13.1, involved in the mycoparasitism of Trichoderma harzianum Cruz Díaz, Jesús de la; Pintor Toro, José Antonio; Benítez Fernández, Concepción Tahía; Llobell González, Antonio; Romero González, Luis Carlos (American Society for Microbiology, 1995) The mycoparasitic fungus Trichoderma harzianum CECT 2413 produces at least three extracellular β-1,3-glucanases. The most ...
Tesis Doctoral Purificación y caracterización de hidrolasas implicadas en el microparasitismo de Trichoderma harzianum Cruz Díaz, Jesús de la; Benítez Fernández, Concepción Tahía; Llobell González, Antonio (1994) Los hongos del genero Trichoderma son buenos agentes de control biológico. Entre los mecanismos que estos utilizan para ...

Perfil del autor: Cruz Díaz, Jesús de la

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