NombreGarcía-Domínguez, Daniel J.
DepartamentoBioquímica Médica y Biología Molecular e Inmunología
Área de conocimientoBioquímica y Biología Molecular
Categoría profesionalPlan Propio-Acceso
Correo electrónicoSolicitar
         
  • Nº publicaciones

    13

  • Nº visitas

    991

  • Nº descargas

    538


 

Artículo
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Cancer nano-immunotherapy: the novel and promising weapon to fight cancer

García-Domínguez, Daniel J.; López Enriquez, Soledad; Alba Jiménez, Gonzalo; Garnacho Montero, Carmen; Jiménez Cortegana, Carlos; Flores-Campos, Rocío; Cruz Merino, Luis de la; Hajji, Nabil; Sánchez Margalet, Víctor; Hontecillas-Prieto, Lourdes (Mdpi Ag, 2024)
Cancer is a complex disease that, despite advances in treatment and the greater understanding of the tumor biology until ...
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Defining the Emergence of New Immunotherapy Approaches in Breast Cancer: Role of Myeloid-Derived Suppressor Cells

Sánchez León, María Luisa; Jiménez Cortegana, Carlos; Silva Romeiro, Silvia; Garnacho Montero, Carmen; Cruz Merino, Luis de la; García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Sánchez Margalet, Víctor (Mdpi Ag, 2023)
Breast cancer (BC) continues to be the most diagnosed tumor in women and a very heterogeneous disease both inter- and ...
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Obesity and Risk for Lymphoma: Possible Role of Leptin

Jiménez Cortegana, Carlos; Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Zapata, Fernando; Palazón Carrión, Natalia; Sánchez León, María Luisa; Tami, Malika; Pérez Pérez, Antonio; Sánchez Jiménez, Flora; Vilariño García, Teresa; Cruz Merino, Luis de la; Sánchez Margalet, Víctor (MDPI, 2022)
Obesity, which is considered a pandemic due to its high prevalence, is a risk factor for many types of cancers, including ...
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Ewing Sarcoma Meets Epigenetics, Immunology and Nanomedicine: Moving Forward into Novel Therapeutic Strategies

Sánchez Molina, Sara; Figuerola Bou, Elisabet; Sánchez Margalet, Víctor; Cruz Merino, Luis de la; Mora, Jaume; Álava Casado, Enrique de; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes (MDPI, 2022)
Ewing Sarcoma (EWS) is an aggressive bone and soft tissue tumor that mainly affects children, adolescents, and young adults. ...
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Tumor Immune Microenvironment in Lymphoma: Focus on Epigenetics

García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; Palazón Carrión, Natalia; Jiménez Cortegana, Carlos; Sánchez Margalet, Víctor; Cruz Merino, Luis de la (MDPI, 2022)
Lymphoma is a neoplasm arising from B or T lymphocytes or natural killer cells characterized by clonal lymphoproliferation. ...
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Selective histone methyltransferase G9a inhibition reduces metastatic development of Ewing sarcoma through the epigenetic regulation of NEU1

García-Domínguez, Daniel J.; Hajji, Nabil; López Alemany, Roser; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Morón Civanto, Francisco Jesús; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Nature Publishing Group, 2022)
Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor with high susceptibility to metastasize. The underlying ...
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The bitter side of epigenetics: variability and resistance to chemotherapy

Hajji, Nabil; García-Domínguez, Daniel J.; Hontecillas Prieto, Lourdes; O'Neill, Kevin; Álava Casado, Enrique de; Syed, Nelofer (Future Medicine, 2021)
One of the major obstacles to the development of effective new cancer treatments and the main factor for the increasing ...
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Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

García-Domínguez, Daniel J.; Hajji, Nabil; Sánchez Molina, Sara; Figuerola Bou, Elisabet; Martínez de Pablos, Rocío; Espinosa Oliva, Ana María; Flores Campos, Rocío; Robles Frías, María José; Álava Casado, Enrique de; Hontecillas Prieto, Lourdes (Springer Nature, 2021)
Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor of children and young adults in which the principal driver ...
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An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogénesis

García-Domínguez, Daniel J.; Hontecillas-Prieto, Lourdes; Andrés León, Eduardo; Sánchez-Molina, Sara; Rodríguez-Núñez, Pablo; Morón, Francisco J.; Hajji, Nabil; Mackintosh, Carlos; Álava Casado, Enrique de (Public Library of Science, 2020)
The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The ...
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Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

Hontecillas Prieto, Lourdes; Flores Campos, Rocío; Silver, Andrew; Álava Casado, Enrique de; Hajji, Nabil; García-Domínguez, Daniel J. (Frontiers Media S.A., 2020)
Chemotherapy is one of the most established and effective treatments for almost all types of cancer. However, the elevated ...
Tesis Doctoral
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Estudio de los coactivadores transcripcionales TAZ y YAP1 en el sarcoma de Ewing: Implicación en la progresión tumoral e interacción funcional con la proteína de fusión EWS-FLI1

Rodríguez Núñez, Pablo; Álava Casado, Enrique de; Díaz Martín, Juan; García-Domínguez, Daniel J. (2019)
La presente tesis doctoral aborda, por primera vez, el papel funcional de los dos efectores finales de la vía Hippo, TAZ ...
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Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients

Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; Pascual Vaca, Diego; García Mejías, Rosa; Marcilla, David; Ramírez Villar, Gema; Álava Casado, Enrique de (Impact Journals, 2017)
Wilms tumour (WT) is the most common renal tumour in children. Most WT patients respond to chemotherapy, but subsets of ...
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HMGA2 overexpression predicts relapse susceptibility of blastemal Wilms tumor patients

Hontecillas Prieto, Lourdes; García-Domínguez, Daniel J.; García Mejías, Rosa; Ramírez Villar, Gema; Sáez, Carmen; Álava Casado, Enrique de (Impact Journals, 2017)
Wilms tumor (WT) is an embryonal malignant neoplasm of the kidney that accounts for 6–7% of all childhood cancers. WT seems ...