Data

NameCastellano Orozco, Antonio Gonzalo
DepartmentFisiología Médica y Biofísica
Knowledge areaFisiología
Professional categoryCatedrático de Universidad
E-mailRequest
         

  Statistics

  • Items

    15

  • Visits

    1830

  • Downloads

    2670

  Publications

 

Article
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Brugada syndrome masked by complete left bundle branch block: A clinical and functional study of its association with the p.1449Y>H SCN5A variant

Arana Rueda, Eduardo; Pezzotti, María R.; Pedrote, Alonso; Acosta, Juan; Frutos-López, Manuel; Varela, Lourdes M.; García-Fernández, Noelia; Castellano Orozco, Antonio Gonzalo (Wiley Periodicals, LLC., 2021-07-01)
SCN5A gene variants are associated with both Brugada syndrome and conduction disturbances, sometimes expressing an overlapping ...
Article
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PKCα-Mediated Downregulation of RhoA Activity in Depolarized Vascular Smooth Muscle: Synergistic Vasorelaxant Effect of PKCα and ROCK Inhibition

González Montelongo, M. Carmen; Porras González, Cristina; González Montelongo, Rafaela; Revilla Gonzalez, Gonzalo; Pastor, María Dolores; Castellano Orozco, Antonio Gonzalo; Ureña López, Juan (2019-02-18)
Background/Aims: Protein kinase C (PKC)- and RhoA/Rho-associated kinase (ROCK) play important roles in arterial sustained ...
Article
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Urocortin-2 Prevents Dysregulation of Ca2+ Homeostasis and Improves Early Cardiac Remodeling After Ischemia and Reperfusion

Domínguez Rodríguez, Alejandro; Mayoral-González, Isabel; Ávila Medina, Javier; Sánchez de Rojas de Pedro, Eva; Calderón Sánchez, Eva María; Díaz Carrasco, Ignacio; Hmadcha, Abdelkrim; Castellano Orozco, Antonio Gonzalo; Ordóñez Fernández, Antonio; Smani Hajami, Tarik (Frontiers Research Foundation, 2018-07-03)
Aims: Urocortin-2 (Ucn-2) is a potent cardioprotector against Ischemia and Reperfusion (I/R) injuries. However, little is ...
PhD Thesis
PhD Thesis
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Regulación por dexametasona del canal de ca2 + tipo t cav3.2 en cardiomiocitos. Implicaciones en la hipertrofia cardíaca

Castellano Orozco, Antonio Gonzalo; Falcón Boyano, Débora (2016-06-01)
Los glucocorticoides son hormonas esteroideas necesarias para la vida que son sintetizadas y liberadas por la glándula ...
Article
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Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells

Ávila Medina, Javier; Calderón Sánchez, Eva María; González-Rodríguez, Patricia; Monje Quiroga, Francisco; Rosado, Juan Antonio; Castellano Orozco, Antonio Gonzalo; Ordóñez Fernández, José Antonio; Smani Hajami, Tarik (American Society for Biochemistry and Molecular Biology, 2016-01-01)
Voltage-dependent CaV1.2 L-type Ca2 channels (LTCC) are the main route for calcium entry in vascular smooth muscle ...
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Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia

Romero-Ruiz, Antonio; Bautista, Lucía; Navarro, Virginia; Heras Garvín, Antonio; Castellano Orozco, Antonio Gonzalo; López Barneo, José; Pascual, Alberto (American Society for Biochemistry and Molecular Biology, 2012-02-03)
Early adaptive responses to hypoxia are essential for cell survival, but their nature and underlying mechanisms are poorly ...
PhD Thesis
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Hipoxia en cardiomiocitos; regulación de la expresión de la subunidad b1 del canal maxi-k y participación en el precondicionamiento cardíaco

Castellano Orozco, Antonio Gonzalo; López Barneo, José; Bautista Borrego, Lucía (2009-03-09)
The presence of maxi-K channels has been reported in the mitochondria of the cardiac myocytes where it plays a cytoprotective ...
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Multiple Facets of Maxi-K Channels: The Heme Connection

López Barneo, José; Castellano Orozco, Antonio Gonzalo (2005-01-01)
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Collapse of conductance Is prevented by a Glutamate residue conserved in voltage-dependent K+ channels

Ortega Sáenz, Patricia; Pardal Redondo, Ricardo; Castellano Orozco, Antonio Gonzalo; López Barneo, José (2000-01-01)
Voltage-dependent K 1 channel gating is influenced by the permeating ions. Extracellular K 1 determines the occupation of ...
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A Small Domain in the N Terminus of the Regulatory a-Subunit Kv2.3 Modulates Kv2.1 Potassium Channel Gating

Chiara, María D.; Monje Quiroga, Francisco; Castellano Orozco, Antonio Gonzalo; López Barneo, José (1999-01-01)
Recent work has demonstrated the existence of regulatory K1 channel a-subunits that are electrically silent but capable ...
Article
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Identification and Functional Characterization of a K1 Channel a- Subunit with Regulatory Properties Specific to Brain

Castellano Orozco, Antonio Gonzalo; Chiara, María D.; Mellström, Britt; Molina, Antonio; Monje Quiroga, Francisco; Naranjo, José R.; López Barneo, José (1997-01-01)
The physiological diversity of K1 channels mainly depends on the expression of several genes encoding different a-subunits. ...
Article
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Sodium and Calcium Currents in Dispersed Mammalian Septal Neurons

López Barneo, José; Castellano Orozco, Antonio Gonzalo (1991-01-01)
Voltage-gated Na+ and Ca2+ conductances of freshly dissociated septal neurons were studied in the whole-cell configuration ...
Article
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Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons

López Barneo, José; Castellano Orozco, Antonio Gonzalo; Toledo Aral, Juan José (1990-01-01)
The interaction of thyrotropin-releasing hormone (TRH) and its physiological metabolite TRH-OH with Na+ channels was studied ...
PhD Thesis
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Canales iónicos de neuronas septales aisladas: Caracterización electrofisiológica y modulación por TRH y LHRH

López Barneo, José; Castellano Orozco, Antonio Gonzalo (1989-10-02)
El presente trabajo continua con una de las líneas de investigación de nuestro grupo que trata del estudio de las propiedades ...