NameCaballero Velázquez, Teresa
DepartmentMedicina
Knowledge areaMedicina
Professional categoryProfesora Contratada Doctora (Plaza Vinc.)
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  • No. publications

    26

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Impact of disease burden and late loss of B cell aplasia on the risk of relapse after CD19 chimeric antigen receptor T Cell (Tisagenlecleucel) infusion in pediatric and young adult patients with relapse/refractory acute lymphoblastic leukemia: role of B-cell monitoring

Molinos-Quintana, Águeda; Alonso-Saladrigues, Anna; Herrero, Blanca; Caballero Velázquez, Teresa; Galán-Gómez, Víctor; Panesso, Melissa; Torrebadell, Montserrat; Delgado-Serrano, Javier; Pérez de Soto, Concepción; Pérez Simón, José Antonio (Frontiers Media S.A., 2024)
Introduction: Loss of B-cell aplasia (BCA) is a well-known marker of functional loss of CD19 CAR-T. Most relapses and loss ...
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Hematological Neoplasms with Eosinophilia

Morales-Camacho, R.M.; Caballero Velázquez, Teresa; Borrero, J.J.; Bernal, R.; Prats-Martín, C. (MDPI, 2024)
The diagnostic assessment of eosinophilias is complex, requiring a multidisciplinary approach and often involving diagnostic ...
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Cannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions

Medrano, M.; Contreras, M.; Caballero Velázquez, Teresa; Martínez, L.; Bejarano-García, J. A.; Calderón Ruiz, Rocío; García-Calderón, C. B.; Valle Rosado, Iván; Pérez Simón, José Antonio (Nature Publishing Group, 2024)
BACKGROUND: Several studies have described a potential anti-tumour effect of cannabinoids (CNB). CNB receptor 2 (CB2) is ...
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Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice

Ramos, Fernando; Hermosín, María Lourdes; Fuertes-Núñez, Marta; Martínez, Pilar; Rodriguez-Medina, Carlos; Barrios, Manuel; Ibáñez, Francisco; Bernal, Teresa; Olave, Maria Teresa; Álvarez, Miguel Ángel; Caballero Velázquez, Teresa; Serrano, Josefina (MPDI, 2023)
Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation ...
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Prognostic value of measurable residual disease in patients with AML undergoing HSCT: a multicenter study

Caballero Velázquez, Teresa; Pérez-López, Olga; Yeguas Bermejo, Ana; Rodríguez Arbolí, Eduardo; Colado Varela, Enrique; Sempere Talens, Amparo; Pérez Simón, José Antonio (MDPI, 2023)
Allogeneic hematopoietic stem cell transplantation (HSCT) represents the best therapeutic option for many patients with ...
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Targeting Hedgehog Signaling with Glasdegib in Patients with Refractory Sclerotic Chronic GVHD: A Report of Two Phase I/II Trials

Rodríguez-Arbolí, Eduardo; Lee, Catherine J; Caballero Velázquez, Teresa; Martinez, Carmen; García Calderón, Clara Beatriz; Jiménez León, María Reyes; Bermudez-Rodriguez, Maria Aranzazu; Pérez Simón, José Antonio (American Association for Cancer Research, 2023)
Purpose: Sclerotic chronic GVHD (scGVHD) is characterized by progressive skin fibrosis and frequent refractoriness to ...
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Monitoring of kinetics and exhaustion markers of circulating CAR-T cells as early predictive factors in patients with B-cell malignancies

García Calderón, Clara Beatriz; Sierro-Martínez, Belén; García-Guerrero, Estefanía; Sanoja-Flores, Luzalba; Muñoz-García, Raquel; Ruiz-Maldonado, Victoria; Carrasco-Brocal, Inmaculada; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (Frontiers Media, 2023)
Purpose: CAR-T cell therapy has proven to be a disruptive treatment in the hematology field, however, less than 50% of ...
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Combined treatment of graft versus host disease using donor regulatory T cells and ruxolitinib

Rodríguez Gil, Alfonso; Escamilla Gómez, Virginia; Nufer, Melanie; Andújar Sánchez, Félix; Lopes Ramos, Teresa; Bejarano García, José Antonio; Caballero Velázquez, Teresa; Villadiego Luque, Francisco Javier; Pérez Simón, José Antonio (Nature Publishing Group, 2022)
Donor derived regulatory T lymphocytes and the JAK1/2 kinase inhibitor ruxolitinib are currently being evaluated as ...
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Phase II Trial of Allogeneic Transplantation Plus Novel Drugs in Multiple Myeloma: Effect of Intensifying Reduced-Intensity Conditioning with Bortezomib and Adding Maintenance Treatment

Reinoso-Segura, Marta; Caballero Velázquez, Teresa; Herrera, Pilar; Patriarca, Francesca; Herrera, Pilar; Fanin, Renato; Bruno, Benedetto; Gahrton, Gösta; Pérez Simón, José Antonio (Elsevier Inc., 2022)
The use of reduced-intensity conditioning (RIC) regimens has decreased the risk of nonrelapse mortality (NRM) after ...
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Delayed administration of ixazomib modifies the immune response and prevents chronic graft-versus-host disease

Ramos, Teresa L.; García Guerrero, Estefanía; Caballero Velázquez, Teresa; Rodríguez Gil, Alfonso; Caracuel García, Rocío; Nufer, Melanie; Robles Frías, María José; Barbado González, Mª Victoria; Pérez Simón, José Antonio (Nature Publishing Group, 2021)
In this study, we aimed to modify the immune response in the long term after allogeneic bone marrow transplantation ...
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High-Dimensional Analysis of Single-Cell Flow Cytometry Data Predicts Relapse in Childhood Acute Lymphoblastic Leukaemia

Chulián, Salvador; Martínez-Rubio, Álvaro; Pérez-García, Víctor M.; Rosa, María; Blázquez Goñi, Cristina; Rodríguez Gutiérrez, Juan Francisco; Caballero Velázquez, Teresa; Fernández-Martínez, Juan Luis (MDPI, 2021)
Artificial intelligence methods may help in unveiling information that is hidden in high-dimensional oncological data. ...
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Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model

Alvarez Laderas, Isabel; Ramos, Teresa L.; Medrano, Mayte; Caracuel García, Rocío; Barbado, María Victoria; Sánchez Hidalgo, Marina; Zamora, Rosario; Alarcón de la Lastra Romero, Catalina; Hidalgo, Francisco J.; Piruat, José Ignacio; Caballero Velázquez, Teresa; Pérez Simón, José Antonio (Elsevier, 2020)
Polyphenols are a group of chemical substances found in plants, with immunomodulatory, antiproliferative, and anti-inflammatory ...
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ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype

Prats-Martín, Concepción; Burillo-Sanz, Sergio; Morales-Camacho, Rosario M.; Pérez-López, Olga; Suito, Milagros; Vargas de los Monteros, María Teresa; Caballero Velázquez, Teresa; Pérez Simón, José Antonio (Wiley Open Access, 2020)
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) are poor outcome leukemias. Its diagnosis is based ...
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Efficacy of bortezomib to intensify the conditioning regimen and the graft-versus-host disease prophylaxis for high-risk myeloma patients undergoing transplantation

Caballero Velázquez, Teresa; Calderón Cabrera, Cristina; López-Corral, L.; Puig, N.; Marquez-Malaver, F.; Pérez-López, E.; Pérez Simón, José Antonio (Springer Nature, 2020)
This multicenter phase I trial was designed to evaluate the safety and efficacy of bortezomib (Bz) as part of both the ...
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Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study

Escamilla Gómez, Virginia; García-Gutiérrez, Valentín; López Corral, Lucía; García Cadenas, Irene; Pérez Martínez, Ariadna; Márquez Malaver, Francisco J.; Caballero Velázquez, Teresa; Espigado Tocino, Ildefonso; Pérez Simón, José Antonio (Springer Nature, 2020)
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. ...
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Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting

Afram, Gabriel; Pérez Simón, José Antonio; Remberger, Mats; Caballero Velázquez, Teresa; Martino, Rodrigo; Piñana, Jose Luis; Ringden, Olle; Esquirol, Albert; Lopez-Corral, Lucia; Hägglund, Hans (Springer, 2018)
Chronic graft-versus-host disease (cGVHD) remains a major cause of morbidity and mortality after allogeneic hematopoietic ...
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Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: “Doublet Technology”

García Guerrero, Estefanía; Sánchez Abarca, Luis Ignacio; Domingo, Esther; Ramos, Teresa L.; Bejarano García, José Antonio; González Campos, José; Caballero Velázquez, Teresa; Pérez Simón, José Antonio (Frontiers Media, S.A., 2018)
The relevance of the immune system in cancer has long been studied. Autologous adoptive T cell therapies, based on the use ...
PhD Thesis
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Nuevas modalidades de inmunoprofilaxis en trasplante: Inhibidores del proteosoma

Calderón Cabrera, Cristina; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (2017)
El trasplante alogénico de progenitores hematopoyéticos es una opción potencialmente curativa para numerosos pacientes con ...
PhD Thesis
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Nuevas estrategias y mecanismos de inmunomodulación en el tratamiento de las hemopatías malignas.

Álvarez Laderas, Isabel; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (2017)
PhD Thesis
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Efecto inmunomodulador de la vitamina D en el periodo postrasplante alogénico de progenitores hematopoyéticos

Montero Cuadrado, María Isabel; Pérez Simón, José Antonio; Caballero Velázquez, Teresa (2016)
El presente trabajo de tesis se basa en un ensayo clínico multicéntrico realizado a nivel nacional sobre una población de ...
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Sensitivity of hematopoietic stem cells to mitochondrial dysfunction by SdhD gene deletion

Bejarano García, José Antonio; Millán-Uclés, África; Valle Rosado, Iván; Sánchez Abarca, Luis Ignacio; Caballero Velázquez, Teresa; Durán Galván, María José; Pérez Simón, José Antonio; Piraut Palomo, José Ignacio (2016)
It is established that hematopoietic stem cells (HSC) in the hypoxic bone marrow have adapted their metabolism to ...
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Caspase-8 inhibition represses initial human monocyte activation in septic shock model

Oliva Martín, María José; Sánchez Abarca, Luis Ignacio; Rodhe, Johanna; Carrillo Jiménez, Alejandro; Vlachos, Pinelopi; Herrera Carmona, Antonio José; García Quintanilla, Alberto; Caballero Velázquez, Teresa; Venero Recio, José Luis (Impact Journals, 2016)
In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic ...
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Human Bone Marrow Stromal Cells Differentiate Into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice

Sánchez Abarca, Luis Ignacio; Hernández Galilea, Emiliano; Lorenzo, Rebeca; Herrero, Carmen; Verlasco, Almudena; Carrancio, Soraya; Caballero Velázquez, Teresa; Rodríguez Barbosa, José Ignacio; Parrilla, Marta; Del Cañizo, Consuelo; San Miguel, Jesús; Aijón, José; Pérez Simón, José Antonio (SAGE Journals, 2015)
Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related ...
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Differential cytogenetic profile in advanced chronic myeloid leukemia with sequential lymphoblastic and myeloblastic blast crisis

Calderón Cabrera, Cristina; Montero, I.; Morales, R. M.; Sánchez, J.; Carrillo, E.; Caballero Velázquez, Teresa; Prats, C.; Bernal, R.; De Blas, J. M.; Pérez Simón, José Antonio (Elsevier, 2013)
Frequency of additional chromosomal abnormalities in chronic myeloid leukemia (CML) is estimated to be 7% in chronic phase ...
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The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation

Caballero Velázquez, Teresa; Sánchez-Abarca, Luis Ignacio; Gutiérrez-Cosío, Silvia; Blanco, Belén; Calderón, Cristina; Herrero, Carmen; Carrancio, Soraya; Serrano, Concepción; del Cañizo, Consuelo; San Miguel, Jesús F.; Pérez Simón, José Antonio (Ferrata Storti Foundation, 2012)
Background We have previously shown that bortezomib induces a depletion of alloreactive T cells and allows the expansion ...
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Evaluation of prognostic factors among patients with chronic graft-versus-host disease

Pérez Simón, José Antonio; Afram, Gabriel; Martino, Rodrigo; Piñana, José L.; Caballero Velázquez, Teresa; Ringden, Olle; Valcárcel, D.; Caballero, Dolores; Remberger, Mats; De Paz, Yanira; Sierra, Jordi; San Miguel, Jesús; Hagglund, Hans;  (Ferrata-Storti Foundation, 2011)
Background: Chronic graft-versus-host disease (cGVHD) is a major complication after allogeneic stem cell transplantation ...