Perfil del autor: Jimeno González, Silvia
Datos institucionales
Nombre | Jimeno González, Silvia |
Departamento | Genética |
Área de conocimiento | Genética |
Categoría profesional | Profesora Titular de Universidad |
Correo electrónico | Solicitar |
Estadísticas
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Nº publicaciones
14
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Nº visitas
2402
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Nº descargas
3411
Publicaciones |
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Artículo
Cell consequences of loss of function of the epigenetic factor EHMT1
(Elsevier, 2023)
EHMT1 is an epigenetic factor with histone methyltransferase activity that appears mutated in Kleefstra syndrome, a ... |
Capítulo de Libro
Un ciclo de mejora docente para estudiar Evolución Molecular
(Universidad de Sevilla, 2022)
En asignaturas de genética, aprender a resolver problemas es esencial para fortalecer la integración de los conceptos que ... |
Artículo
ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair
(Nature Publishing Group, 2021)
The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA ... |
Artículo
Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
(Elsevier, 2021)
Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol ... |
Artículo
Human prefoldin modulates co-transcriptional pre-mRNA splicing
(Oxford University Press, 2021)
Prefoldin is a heterohexameric complex conserved from archaea to humans that plays a cochaperone role during the ... |
Tesis Doctoral
Regulación transcripcional mediada por la DNA topoisomerasa II
(2020)
La topología del DNA condiciona todos los procesos del metabolismo cromosómico y, en especial, la transcripción, ya que ... |
Artículo
Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency
(Springer Nature, 2020)
The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ... |
Artículo
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme
(Nature Publishing Group, 2017)
Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate ... |
Artículo
A positioned +1 nucleosome enhances promoter-proximal pausing
(Oxford University Press, 2015)
Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free ... |
Artículo
Rat1p maintains RNA polymerase II CTD phosphorylation balance
(Cold Spring Harbor Laboratory Press, 2014)
In S. cerevisiae, the 5′-3′ exonuclease Rat1p partakes in transcription termination. Although Rat1p-mediated RNA degradation ... |
Artículo
Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes
(EMBO Press, 2009)
For efficient transcription, RNA PolII must overcome the presence of nucleosomes. The p38-related MAPK Hog1 is an important ... |
Artículo
Regulon-Specific Control of Transcription Elongation across the Yeast Genome
(Public Library of Science, 2009)
Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide ... |
Artículo
Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription
(Public Library of Science, 2009)
Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that ... |
Artículo
A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region
(2006)
The FACT complex stimulates transcription elongation on nucleosomal templates. In vivo experiments also involve FACT in ... |