Data

NameJimeno González, Silvia
DepartmentGenética
Knowledge areaGenética
Professional categoryProfesora Contratada Doctora
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  Statistics

  • Items

    12

  • Visits

    1686

  • Downloads

    2211

  Publications

 

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Human prefoldin modulates co-transcriptional pre-mRNA splicing

Payán Bravo, Laura; Fontalva Ostio, Sara; Peñate Salas, Xenia; Cases, Ildefonso; Guerrero Martínez, José A.; Pareja Sánchez, Yerma; Odriozola Gil, Yosu; Lara, Esther; Jimeno González, Silvia; Suñé Negre, Carlos María; Muñoz Centeno, María de la Cruz; Reyes, José C.; Chávez de Diego, Sebastián (Oxford University Press, 2021-01-01)
Prefoldin is a heterohexameric complex conserved from archaea to humans that plays a cochaperone role during the ...
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ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

Jimeno González, Sonia; Prados Carvajal, Rosario; Fernández Ávila, María Jesús; Pinela Da Silva, Sonia Cristina; Silvestris, Domenico Alessandro; Endara Coll, Martin; Rodríguez Real, Guillermo; Domingo Prim, Judit; Mejías Navarro, Fernando; Romero Franco, Amador; Jimeno González, Silvia; Barroso, Sonia; Cesarini, Valeriana; Aguilera López, Andrés; Gallo, Angela; Visa, Neus; Huertas Sánchez, Pablo (Nature Publishing Group, 2021-01-01)
The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA ...
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Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

Herrero Ruiz, Andrés M.; Martínez García, Pedro Manuel; Terrón Bautista, José; Millán Zambrano, Gonzalo; Lieberman, Jenna Ariel; Jimeno González, Silvia; Cortés Ledesma, Felipe (Elsevier, 2021-01-01)
Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol ...
PhD Thesis
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Regulación transcripcional mediada por la DNA topoisomerasa II

Cortés Ledesma, Felipe; Jimeno González, Silvia; Herrero Ruiz, Andrés M. (2020-02-18)
La topología del DNA condiciona todos los procesos del metabolismo cromosómico y, en especial, la transcripción, ya que ...
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Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

Álvarez Quilón, Alejandro; Terrón Bautista, José; Delgado Sainz, Irene; Serrano Benítez, Almudena; Romero Granados, Rocío; Martínez García, Pedro Manuel; Jimeno González, Silvia; Bernal Lozano, Cristina; Quintero, Cristina; García Quintanilla, Lourdes; Cortés Ledesma, Felipe (Springer Nature, 2020-01-01)
The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ...
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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

Feng, Weijun; Kawauchi, Daisuke; Körkel-Qu, Huiqin; Ariel Lieberman, Jenna; Jimeno González, Silvia; Cortés Ledesma, Felipe (Nature Publishing Group, 2017-01-01)
Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate ...
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A positioned +1 nucleosome enhances promoter-proximal pausing

Jimeno González, Silvia; Ceballos Chávez, María; Reyes , José Carlos (Oxford University Press, 2015-01-01)
Chromatin distribution is not uniform along the human genome. In most genes there is a promoter-associated nucleosome free ...
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Rat1p maintains RNA polymerase II CTD phosphorylation balance

Jimeno González, Silvia; Schmid, Manfred; Malagón Cobos, Francisco; Haaning, Line Lindegaard; Jensen, Torben Heick (Cold Spring Harbor Laboratory Press, 2014-01-01)
In S. cerevisiae, the 5′-3′ exonuclease Rat1p partakes in transcription termination. Although Rat1p-mediated RNA degradation ...
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Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes

Mas, Glòria; Nadal, Eulàlia de; Reinhard Dechant; Rodríguez de la Concepción, María Luisa; Logie, Colin; Jimeno González, Silvia; Chávez de Diego, Sebastián (EMBO Press, 2009-01-01)
For efficient transcription, RNA PolII must overcome the presence of nucleosomes. The p38-related MAPK Hog1 is an important ...
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Regulon-Specific Control of Transcription Elongation across the Yeast Genome

Pelechano, Vicent; Jimeno González, Silvia; Rodríguez Gil, Alfonso; García Martínez, José; Pérez Ortín, José E.; Chávez de Diego, Sebastián (Public Library of Science, 2009-01-01)
Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide ...
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Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription

Vanti, Manuela; Gallastegui, Edurne; Respaldiza, Iñaki; Rodríguez Gil, Alfonso; Gómez Herreros, Fernando; Jimeno González, Silvia; Chávez de Diego, Sebastián (Public Library of Science, 2009-01-01)
Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that ...
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A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region

Jimeno González, Silvia; Gómez Herreros, Fernando; Alepuz, Paula M.; Chávez de Diego, Sebastián (2006-01-01)
The FACT complex stimulates transcription elongation on nucleosomal templates. In vivo experiments also involve FACT in ...