Data

NameGómez Herreros, Fernando
DepartmentGenética
Knowledge areaGenética
Professional categoryProfesor Contratado Doctor
E-mailRequest
           

  Statistics

  • Items

    12

  • Visits

    1033

  • Downloads

    1155

  Publications

 

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Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity

Olmedo Pelayo, Joaquín; Rubio Contreras, Diana; Gómez Herreros, Fernando (Oxford University Press, 2020-01-01)
DNA topoisomerase II (TOP2) is a major DNA metabolic enzyme, with important roles in replication, transcription, chromosome ...
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FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress

Martínez Macías, María Isabel; Green, Ryan L.; Gómez Herreros, Fernando; Naumann, Marcel; Hermann, Andreas; Hafezparast, Majid; Caldecott, Keith W.; Moore, Duncan A. Q.; Damme, Philip Van (Rockefeller University Press, 2019-02-26)
FUS (fused in sarcoma) plays a key role in several steps of RNA metabolism, and dominant mutations in this protein are ...
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DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II

Gómez Herreros, Fernando (Frontiers Media, 2019-01-01)
DNA double strand breaks (DSBs) are the most cytotoxic lesions of those occurring in the DNA and can lead to cell death ...
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TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription

Gómez Herreros, Fernando; Zagnoli Vieira, Guido; Ntai, Ioanna; Martínez Macías, María Isabel; Anderson, Rhona M.; Herrero Ruíz, Andrés; Caldecott, Keith W. (Nature Publishing Group, 2017-01-01)
DNA double-strand breaks (DSBs) induced by abortive topoisomerase II (TOP2) activity are a potential source of genome ...
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The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation

Gómez Herreros, Fernando; Margaritis, Thanasis; Rodríguez Galán, Olga; Pelechano, Vicent; Begley, Victoria Sarah; Millán Zambrano, Gonzalo; Morillo Huesca, Macarena; Muñoz Centeno, María de la Cruz; Pérez Ortín, José Enrique; Cruz Díaz, Jesús de la; Holstege, Frank C.P.; Chávez de Diego, Sebastián (Oxford University Press, 2017-01-01)
Ribosome assembly requires the concerted expression of hundreds of genes, which are transcribed by all three nuclear RNA ...
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Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

Maciejewski, Sonia; Nguyen, Joseph H. C.; Gómez Herreros, Fernando; Cortés Ledesma, Felipe; Caldecott, Keith W.; Semler, Bert L. (American Society for Microbiology, 2015-12-01)
Viruses of the Enterovirus genus of picornaviruses, including poliovirus, coxsackievirus B3 (CVB3), and human rhinovirus, ...
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TDP2-Dependent Non-Homologous End-Joining Protects against Topoisomerase II-Induced DNA Breaks and Genome Instability in Cells and In Vivo

Gómez Herreros, Fernando; Romero Granados, Rocío; Zeng, Zhihong; Álvarez Quilón, Alejandro; Quintero Ruiz, María Cristina; Ju, Limei; Umans, Lieve; Vemeire, Liesbeth; Huylebroeck, Danny; Caldecott, Keith W.; Cortés Ledesma, Felipe (Public Library of Science, 2013-01-01)
Anticancer topoisomerase >poisons> exploit the break-and-rejoining mechanism of topoisomerase II (TOP2) to generate ...
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Balanced production of ribosome components is required for proper G/S transition in saccharomyces cerevisiae

Gómez Herreros, Fernando; Rodríguez Galán, Olga; Morillo Huesca, Macarena; Maya, Douglas; Arista Romero, María; Cruz Díaz, Jesús de la; Chávez de Diego, Sebastián; Muñoz Centeno, María de la Cruz (American Society for Biochemistry and Molecular Biology Inc., 2013-01-01)
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TFIIS is required for the balanced expression of the genes encoding ribosomal components under transcriptional stress

Gómez Herreros, Fernando; Miguel Jiménez, María Dolores de; Morillo Huesca, Macarena; Delgado Ramos, Lidia; Muñoz Centeno, María de la Cruz; Chávez de Diego, Sebastián (Oxford University Press, 2012-01-01)
Transcription factor IIS (TFIIS) stimulates RNA cleavage by RNA polymerase II by allowing backtracked enzymes to resume ...
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One step back before moving forward: regulation of transcription elongation by arrest and backtracking

Gómez Herreros, Fernando; Miguel Jiménez, María Dolores De; Millán Zambrano, Gonzalo; Peñate Salas, Xenia; Delgado Ramos, Lidia; Muñoz Centeno, María de la Cruz; Chávez de Diego, Sebastián (Wiley-Blackwell, 2012-01-01)
RNA polymerase II backtracking is a well-known phenomenon, but its involvement in gene regulation is yet to be addressed. ...
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Yeast Genetic Analysis Reveals the Involvement of Chromatin Reassembly Factors in Repressing HIV-1 Basal Transcription

Vanti, Manuela; Gallastegui, Edurne; Respaldiza, Iñaki; Rodríguez Gil, Alfonso; Gómez Herreros, Fernando; Jimeno González, Silvia; Chávez de Diego, Sebastián (Public Library of Science, 2009-01-01)
Rebound of HIV viremia after interruption of anti-retroviral therapy is due to the small population of CD4+ T cells that ...
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A gene-specific requirement for FACT during transcription is related to the chromatin organization of the transcribed region

Jimeno González, Silvia; Gómez Herreros, Fernando; Alepuz, Paula M.; Chávez de Diego, Sebastián (2006-01-01)
The FACT complex stimulates transcription elongation on nucleosomal templates. In vivo experiments also involve FACT in ...