Perfil del autor: Ruiz Pérez, José Francisco
Datos institucionales
Nombre | Ruiz Pérez, José Francisco |
Departamento | Bioquímica Vegetal y Biología Molecular |
Área de conocimiento | Bioquímica y Biología Molecular |
Categoría profesional | Profesor Titular de Universidad |
Correo electrónico | Solicitar |
Estadísticas
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Nº publicaciones
14
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Nº visitas
2403
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Nº descargas
2800
Publicaciones |
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Trabajo Fin de Grado
Herramientas CRISPR-Cas9 y la posible cura de enfermedades genéticas en humanos: el caso de la anemia falciforme
(2023)
Con el avance en el conocimiento de las herramientas de edición génica, la posibilidad de producir modificaciones específicas ... |
Artículo
An End to a Means: How DNA-End Structure Shapes the Double-Strand Break Repair Process
(Frontiers Media, 2020)
Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5'-phosphate, 3'-hydroxyl moieties at the ... |
Artículo
Regulation of human Polλ by ATM-mediated phosphorylation during Non-Homologous End Joining
(Elsevier, 2018)
DNA double strand breaks (DSBs) trigger a variety of cellular signaling processes, collectively termed the DNA-damage ... |
Artículo
Polμ tumor variants decrease the efficiency and accuracy of NHEJ
(Oxford University Press, 2017)
The non homologous end-joining (NHEJ) pathway of double-strand break (DSB) repair often requires DNA synthesis to fill the ... |
Artículo
A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination
(Public Library of Science, 2017)
Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ... |
Artículo |
Artículo
AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants
(Public Library of Science, 2011)
Transcription of the switch (S) regions of immunoglobulin genes in B cells generates stable R-loops that are targeted by ... |
Artículo
Chromosomal translocations caused by either Pol32-dependent or Pol32-independent triparental break-induced replication
(American Society for Microbiology, 2009)
Double-strand breaks (DSBs) are harmful DNA lesions that can generate chromosomal rearrangements or chromosome losses if ... |
Artículo
A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis
(Oxford University Press, 2006)
Human DNA polymerase mu (Polm) is a family X member that has terminal transferase activity but, in spite of a non-orthodox ... |
Artículo
Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe
(Oxford University Press, 2005)
As predicted by the amino acid sequence, the purified protein coded by Schizosaccharomyces pombe SPAC2F7.06c is a DNA ... |
Artículo |
Artículo
Are there mutator polymerases?
(Hindawi Publishing Corporation, 2003)
DNA polymerases are involved in different cellular events, including genome replication and DNA repair. In the last few ... |
Artículo |
Artículo
DNA polymerase λ, a novel DNA repair enzyme in human cells
(American Society for Biochemistry and Molecular Biology Inc., 2002)
DNA polymerase lambda (pol λ) is a novel family X DNA polymerase that has been suggested to play a role in meiotic ... |