idUS - Perfil del autor: Ruiz Pérez, José Francisco

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Nombre	Ruiz Pérez, José Francisco
Departamento	Bioquímica Vegetal y Biología Molecular
Área de conocimiento	Bioquímica y Biología Molecular
Categoría profesional	Profesor Titular de Universidad
Correo electrónico	Solicitar

Nº publicaciones

14
Nº visitas

1740
Nº descargas

2370

Tipología

Orden

Publicaciones
Trabajo Fin de Grado Herramientas CRISPR-Cas9 y la posible cura de enfermedades genéticas en humanos: el caso de la anemia falciforme. González Sainz, Julia; Ruiz Pérez, José Francisco (2023) Con el avance en el conocimiento de las herramientas de edición génica, la posibilidad de producir modificaciones específicas ...
Artículo An End to a Means: How DNA-End Structure Shapes the Double-Strand Break Repair Process Serrano Benítez, Almudena; Cortés Ledesma, Felipe; Ruiz Pérez, José Francisco (Frontiers Media, 2020) Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5'-phosphate, 3'-hydroxyl moieties at the ...
Artículo Regulation of human Polλ by ATM-mediated phosphorylation during Non-Homologous End Joining Sastre Moreno, Guillermo; Pryor, John M.; Moreno Oñate, Marta; Herrero Ruiz, Andrés M.; Cortés Ledesma, Felipe; Ruiz Pérez, José Francisco (Elsevier, 2018) DNA double strand breaks (DSBs) trigger a variety of cellular signaling processes, collectively termed the DNA-damage ...
Artículo Polμ tumor variants decrease the efficiency and accuracy of NHEJ Sastre Moreno, Guillermo; Pryor, John M.; Díaz Talavera, Alberto; Ruiz Pérez, José Francisco; Ramsden, Dale A.; Blanco, Luis (Oxford University Press, 2017) The non homologous end-joining (NHEJ) pathway of double-strand break (DSB) repair often requires DNA synthesis to fill the ...
Artículo A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination Muñoz Galván, Sandra; García Rubio, María Luisa; Ortega Moreno, Pedro; Ruiz Pérez, José Francisco; Jimeno González, Sonia; Pardo, Benjamín; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017) Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
Artículo Yeast pol4 promotes tel1-regulated chromosomal translocations Sastre Moreno, Guillermo; Aguilera López, Andrés; Ruiz Pérez, José Francisco; Pardo, Benjamín; Blanco Dávila, Luis (2013)
Artículo AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants Ruiz Pérez, José Francisco; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2011) Transcription of the switch (S) regions of immunoglobulin genes in B cells generates stable R-loops that are targeted by ...
Artículo Chromosomal translocations caused by either Pol32-dependent or Pol32-independent triparental break-induced replication Ruiz Pérez, José Francisco; Gómez González, Belén; Aguilera López, Andrés (American Society for Microbiology, 2009) Double-strand breaks (DSBs) are harmful DNA lesions that can generate chromosomal rearrangements or chromosome losses if ...
Artículo A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis Juárez, Raquel; Ruiz Pérez, José Francisco; McElhinny, Stephanie A Nick; Ramsden, Dale A.; Blanco, Luis (Oxford University Press, 2006) Human DNA polymerase mu (Polm) is a family X member that has terminal transferase activity but, in spite of a non-orthodox ...
Artículo Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe González Barrera, Sergio; Sánchez, Arancha; Ruiz Pérez, José Francisco; Juárez, Raquel; Picher, Ángel J.; Terrados, Gloria; Andrade, Paula; Blanco, Luis (Oxford University Press, 2005) As predicted by the amino acid sequence, the purified protein coded by Schizosaccharomyces pombe SPAC2F7.06c is a DNA ...
Artículo Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate Piris, Miguel A.; Sáez Castillo, Ana Isabel; Ruiz Pérez, José Francisco; Blanco Dávila, Luis (2004)
Artículo Are there mutator polymerases? García Díaz, Miguel; Ruiz Pérez, José Francisco; Juárez, Raquel; Terrados, Gloria; Blanco, Luis (Hindawi Publishing Corporation, 2003) DNA polymerases are involved in different cellular events, including genome replication and DNA repair. In the last few ...
Artículo Lack of sugar discrimination by human pol requires a single glycine residue Blanco Dávila, Luis; Ruiz Pérez, José Francisco; García Díaz, Miguel; Juárez, Raquel; Terrados, Gloria; Picher, Ángel J.; González Barrera, Sergio; Fernández de Henestrosa, Antonio R. (2003)
Artículo DNA polymerase λ, a novel DNA repair enzyme in human cells García Díaz, Miguel; Bebenek, Katarzyna; Sabariegos, Rosario; Domínguez, Orlando; Rodríguez, Josana Renato; Kirchhoff, Tomas; García Palomero, Esther; Picher, Ángel J.; Juárez, Raquel; Ruiz Pérez, José Francisco; Kunkel, Thomas A.; Blanco, Luis (American Society for Biochemistry and Molecular Biology Inc., 2002) DNA polymerase lambda (pol λ) is a novel family X DNA polymerase that has been suggested to play a role in meiotic ...