Data

NameRuiz Pérez, José Francisco
DepartmentBioquímica Vegetal y Biología Molecular
Knowledge areaBioquímica y Biología Molecular
Professional categoryProfesor Titular de Universidad
E-mailRequest
           

  Statistics

  • Items

    13

  • Visits

    1424

  • Downloads

    1669

  Publications

 

Article
Icon

An End to a Means: How DNA-End Structure Shapes the Double-Strand Break Repair Process

Serrano Benítez, Almudena; Cortés Ledesma, Felipe; Ruiz Pérez, José Francisco (Frontiers Media, 2020-01-01)
Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5'-phosphate, 3'-hydroxyl moieties at the ...
Article
Icon

Regulation of human Polλ by ATM-mediated phosphorylation during Non-Homologous End Joining

Sastre Moreno, Guillermo; Pryor, John M.; Moreno Oñate, Marta; Herrero Ruiz, Andrés M.; Cortés Ledesma, Felipe; Ruiz Pérez, José Francisco (Elsevier, 2018-01-01)
DNA double strand breaks (DSBs) trigger a variety of cellular signaling processes, collectively termed the DNA-damage ...
Article
Icon

A new role for Rrm3 in repair of replication-born DNA breakage by sister chromatid recombination

Muñoz Galván, Sandra; García Rubio, María Luisa; Ortega Moreno, Pedro; Ruiz Pérez, José Francisco; Jimeno González, Sonia; Pardo, Benjamín; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2017-01-01)
Replication forks stall at different DNA obstacles such as those originated by transcription. Fork stalling can lead to ...
Article
Icon

Polμ tumor variants decrease the efficiency and accuracy of NHEJ

Sastre Moreno, Guillermo; Pryor, John M.; Díaz Talavera, Alberto; Ruiz Pérez, José Francisco; Ramsden, Dale A.; Blanco, Luis (Oxford University Press, 2017-01-01)
The non homologous end-joining (NHEJ) pathway of double-strand break (DSB) repair often requires DNA synthesis to fill the ...
Article
Icon

Yeast pol4 promotes tel1-regulated chromosomal translocations

Sastre Moreno, Guillermo; Aguilera López, Andrés; Ruiz Pérez, José Francisco; Pardo, Benjamín; Blanco Dávila, Luis (2013-01-01)
Article
Icon

AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants

Ruiz Pérez, José Francisco; Gómez González, Belén; Aguilera López, Andrés (Public Library of Science, 2011-01-01)
Transcription of the switch (S) regions of immunoglobulin genes in B cells generates stable R-loops that are targeted by ...
Article
Icon

Chromosomal translocations caused by either Pol32-dependent or Pol32-independent triparental break-induced replication

Ruiz Pérez, José Francisco; Gómez González, Belén; Aguilera López, Andrés (American Society for Microbiology, 2009-01-01)
Double-strand breaks (DSBs) are harmful DNA lesions that can generate chromosomal rearrangements or chromosome losses if ...
Article
Icon

A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis

Juárez, Raquel; Ruiz Pérez, José Francisco; McElhinny, Stephanie A Nick; Ramsden, Dale A.; Blanco, Luis (Oxford University Press, 2006-01-01)
Human DNA polymerase mu (Polm) is a family X member that has terminal transferase activity but, in spite of a non-orthodox ...
Article
Icon

Characterization of SpPol4, a unique X-family DNA polymerase in Schizosaccharomyces pombe

González Barrera, Sergio; Sánchez, Arancha; Ruiz Pérez, José Francisco; Juárez, Raquel; Picher, Ángel J.; Terrados, Gloria; Andrade, Paula; Blanco, Luis (Oxford University Press, 2005-01-01)
As predicted by the amino acid sequence, the purified protein coded by Schizosaccharomyces pombe SPAC2F7.06c is a DNA ...
Article
Icon

Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate

Piris, Miguel A.; Sáez Castillo, Ana Isabel; Ruiz Pérez, José Francisco; Blanco Dávila, Luis (2004-01-01)
Article
Icon

Lack of sugar discrimination by human pol requires a single glycine residue

Blanco Dávila, Luis; Ruiz Pérez, José Francisco; García Díaz, Miguel; Juárez, Raquel; Terrados, Gloria; Picher, Ángel J.; González Barrera, Sergio; Fernández de Henestrosa, Antonio R. (2003-01-01)
Article
Icon

Are there mutator polymerases?

García Díaz, Miguel; Ruiz Pérez, José Francisco; Juárez, Raquel; Terrados, Gloria; Blanco, Luis (Hindawi Publishing Corporation, 2003-01-01)
DNA polymerases are involved in different cellular events, including genome replication and DNA repair. In the last few ...
Article
Icon

DNA polymerase λ, a novel DNA repair enzyme in human cells

García Díaz, Miguel; Bebenek, Katarzyna; Sabariegos, Rosario; Domínguez, Orlando; Rodríguez, Josana Renato; Kirchhoff, Tomas; García Palomero, Esther; Picher, Ángel J.; Juárez, Raquel; Ruiz Pérez, José Francisco; Kunkel, Thomas A.; Blanco, Luis (American Society for Biochemistry and Molecular Biology Inc., 2002-01-01)
DNA polymerase lambda (pol λ) is a novel family X DNA polymerase that has been suggested to play a role in meiotic ...