Data

NameRomero Portillo, Francisco
DepartmentMicrobiología
Knowledge areaMicrobiología
Professional categoryCatedrático de Universidad
E-mailRequest
           

  Statistics

  • Items

    17

  • Visits

    1988

  • Downloads

    1750

  Publications

 

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Tubulin Folding Cofactor TBCB is a Target of the Salmonella Effector Protein SseK1

Araujo Garrido, Juan Luis; Baisón Olmo, Fernando; Bernal Bayard, Joaquín; Romero Portillo, Francisco; Ramos Morales, Francisco (MDPI, 2020-01-01)
Salmonella enterica serovar Typhimurium is a human and animal pathogen that uses type III secretion system effectors to ...
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p53 and FBXW7: Sometimes Two Guardians Are Worse than One

Galindo Moreno, María; Giráldez Macías, Servando; Limón Mortés, María Cristina; Belmonte Fernández, Alejandro; Sáez, Carmen; Japón, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (MDPI, 2020-01-01)
Too much of a good thing can become a bad thing. An example is FBXW7, a well-known tumor suppressor that may also contribute ...
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EDIL3 promotes epithelial–mesenchymal transition and paclitaxel resistance through its interaction with integrin αVβ3 in cancer cells

Gasca, Jessica; Flores, María Luz; Jiménez Guerrero, Rocío; Sáez, M. E.; Barragán, Isabel; Ruíz Borrego, Manuel; Tortolero García, María Dolores; Romero Portillo, Francisco; Sáez, Carmen; Japón, Miguel Á. (Springer Nature, 2020-01-01)
Epithelial–mesenchymal transition (EMT) has recently been associated with tumor progression, metastasis, and chemotherapy ...
PhD Thesis
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Importancia de la desregulación de la degradación de proteínas del ciclo celular en el cáncer

Romero Portillo, Francisco; Tortolero García, María Dolores; Galindo Moreno, María (2019-06-14)
La viabilidad de las células depende del buen funcionamiento de un conjunto de mecanismos moleculares que controlan los ...
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Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells

Jiménez Guerrero, Rocío; Gasca Bellido, Jessica María; Flores, M. Luz; Pérez Valderrama, Begoña; Medina, Rafael; Tortolero García, María Dolores; Romero Portillo, Francisco; Japón Rodríguez, Miguel Ángel (MDPI, 2018-01-01)
Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and ...
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Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer

Galindo Moreno, María; Giráldez Macías, Servando; Sáez, Carmen; Japón Rodríguez, Miguel Ángel; Tortolero García, María Dolores; Romero Portillo, Francisco (Nature Publishing Group, 2017-01-01)
Cyclin-dependent kinase 1 (CDK1) is the central mammalian regulator of cell proliferation and a promising therapeutic ...
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Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism

Gavilán Dorronzoro, Elena; Giraldez Macias, Servando; Sánchez Aguayo, Inmaculada; Romero Portillo, Francisco; Ruano Caballero, Diego; Daza Navarro, María Paula (Nature, 2015-01-01)
Targeting the ubiquitin proteasome pathway has emerged as a rational approach in the treatment of human cancers. Autophagy ...
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βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

Herrero Ruiz, Joaquín; Mora Santos, María del Mar; Giraldez Macias, Servando; Sáez Torres, Carmen; Romero Portillo, Francisco; Japón Rodríguez, Miguel Ángel (Impact Journals, 2014-01-01)
n mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the ...
Presentation
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Uso periodístico de las redes sociales : ventajas, obstáculos y riesgos

Romero Portillo, Francisco; Vidal Vega, Javier (Edufora, 2012-01-01)
Desde 2003, las redes sociales se han convertido en una herramienta cotidiana para millones de personas en todo el mundo. ...
PhD Thesis
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Análisis Funcional de la Fosforilación de Securina

Romero Portillo, Francisco; Tortolero García, María Dolores; Mora Santos, María del Mar (2011-01-01)
El objetivo de esta Tesis se engloba dentro de un estudio más amplio sobre el análisis funcional de la fosforilación de ...
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UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase

Limón Mortés, María Cristina; Mora Santos, María del Mar; Espina Zambrano, Águeda Gema; Pintor Toro, José Antonio; López Román, Antonio; Tortolero García, María Dolores; Romero Portillo, Francisco (Company of Biologists, 2008-01-01)
Securin is a chaperone protein with bifunctional properties. It binds to separase to inhibit premature sister chromatid ...
PhD Thesis
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Regulación de la estabilidad de la oncoproteína PTTG1/hSecurina

Romero Portillo, Francisco; Tortolero García, María Dolores; Limón Mortés, María Cristina (2007-01-01)
El objetico de esta Tesis es el estudio de la relación de la estabilidad de la oncoproteína PTTG1/Sec. Para ello nos ...
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Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase

Gil Bernabé, Ana María; Romero Portillo, Francisco; Limón Mortés, María Cristina; Tortolero García, María Dolores (2006-01-01)
Sister chromatid segregation is triggered at the metaphase-to-anaphase transition by the activation of the protease separase. ...
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Securin Is a Target of the UV Response Pathway in Mammalian Cells

Romero Portillo, Francisco; Gil-Bernabé, Ana M.; Sáez, Carmen; Pintor Toro, José Antonio; Tortolero García, María Dolores (2004-01-01)
All eukaryotic cells possess elaborate mechanisms to protect genome integrity and ensure survival after DNA damage, ceasing ...
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Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase

Tortolero García, María Dolores; Romero Portillo, Francisco; Bernal Rodríguez, Juan Antonio; Ramos Morales, Francisco; Domínguez, África (2001-01-01)
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hSiah2 is a new vav binding protein which inhibits Vav-mediated signaling pathways

Germani, Antonia; Romero Portillo, Francisco; Houlard, Martin; Camonis, Jacques H.; Gisselbrecht, Sylvie; Fischer, Siegmund; Varin-Blank, Nadine (1999-01-01)
The hematopoietic proto-oncogene vav has been characterized as a Rac1- GDP/GTP exchanger protein which regulates cytoskeletal ...
PhD Thesis
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Estudio genético de la nodulación de "Rhizobium fredii"

Ruiz Sainz, José Enrique; Romero Portillo, Francisco (1993-01-01)
En esta tesis se han estudiado diversos aspectos de la nodulación de las estirpes de Rhizobium fredii. Esta especie está ...