Data

NamePastor Loro, Ángel Manuel
DepartmentFisiología
Knowledge areaFisiología
Professional categoryCatedrático de Universidad
E-mailRequest
           

  Statistics

  • Items

    34

  • Visits

    3012

  • Downloads

    3712

  Publications

 

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Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro

Herrera Lira, Alejandro; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza (MDPI, 2021-01-01)
Neural progenitor cells (NPCs) are self-renewing and multipotent cells that persist in the postnatal and adult brain in ...
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Neuroprotective Effect of Vascular Endothelial Growth Factor on Motoneurons of the Oculomotor System

Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (MDPI, 2021-01-01)
Vascular endothelial growth factor (VEGF) was initially characterized as a potent angiogenic factor based on its activity ...
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Structural and molecular characteristics of axons in the long head of the biceps tendon

Blumer, Roland; Boesmueller, Sandra E.; Gesslbauer, Bernhard; Hirtler, Lena; Candel Bormann, Daniel; Pastor Loro, Ángel Manuel; Streicher, Johannes; Mittermayr, Rainer (Springer Nature, 2020-01-01)
The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since ...
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Muscle Progenitors Derived from Extraocular Muscles Express Higher Levels of Neurotrophins and their Receptors than other Cranial and Limb Muscles

Carrero Rojas, Génova; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Davis López de Carrizosa, María América (MDPI, 2020-01-01)
Extraocular muscles (EOMs) show resistance to muscle dystrophies and sarcopenia. It has been recently demonstrated that ...
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Functional diversity of motoneurons in the oculomotor system

García Hernández, Rosendo Miguel; Martín Calvo, Paula; Blumer, Roland; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (National Academy of Sciences, 2019-02-26)
Extraocular muscles contain two types of muscle fibers according to their innervation pattern: singly innervated muscle ...
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Neural Stem Cells of the Subventricular Zone as the Origin of Human Glioblastoma Stem Cells. Therapeutic Implications

Rodríguez Matarredona, Esperanza; Pastor Loro, Ángel Manuel (Frontiers Media, 2019-01-01)
Human glioblastoma is the most aggressive type of primary malignant brain tumors. Standard treatment includes surgical ...
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Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment

Rodríguez Matarredona, Esperanza; Pastor Loro, Ángel Manuel (MDPI, 2019-01-01)
The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with ...
PhD Thesis
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Dependencias tróficas y sinápticas del sistema oculomotor.

Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; García Hernández, Rosendo Miguel (2018-02-23)
Las motoneuronas del recto medial presentes en el núcleo motor ocular común (NMOC) reciben dos entradas pontinas principales: ...
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Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat

Acosta, Lourdes; Morcuende Fernández, Sara R.; Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Frontiers Media, 2018-01-01)
Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, ...
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Interactions between neural progenitor cells and microglia in the subventricular zone: physiological implications in the neurogenic niche and after implantation in the injured brain

Rodríguez Matarredona, Esperanza; Talaverón Aguilocho, Rocío; Pastor Loro, Ángel Manuel (Frontiers Media, 2018-01-01)
The adult subventricular zone (SVZ) of the mammalian brain contains neural progenitor cells (NPCs) that continuously produce ...
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Vascular endothelial growth factor: an essential neurotrophic factor for motoneurons?

Martín Calvo, Paula; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Medknow Publications, 2018-01-01)
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Effects of Selective Deafferentation on the Discharge Characteristics of Medial Rectus Motoneurons

Benítez Temiño, Beatriz; Morado Díaz, Camilo José; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; G. Hernández, Rosendo (Society for Neuroscience, 2018-01-01)
Medial rectus motoneurons receive two main pontine inputs: abducens internuclear neurons, whose axons course through the ...
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Extraocular Motor System Exhibits a Higher Expression of Neurotrophins When Compared with Other Brainstem Motor Systems

García Hernández, Rosendo Miguel; Silva Hucha, Silvia; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; Benítez Temiño, Beatriz (Frontiers Media, 2017-01-01)
Extraocular motoneurons resist degeneration in diseases such as amyotrophic lateral sclerosis. The main objective of the ...
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Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons

Silva Hucha, Silvia; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María; Morcuende Fernández, Sara R.; García Hernández, Rosendo Miguel (Public Library of Science, 2017-01-01)
Recent studies show a relationship between the deficit of vascular endothelial growth factor (VEGF) and motoneuronal ...
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Palisade endings of extraocular muscles develop postnatally following different time courses

Blumer, Roland; Streicher, Johannes; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Association for Research in Vision and Ophthalmology, 2017-01-01)
PURPOSE. To analyze in a frontal-eyed mammal (cat) the postnatal development of palisade endings in extraocular muscles ...
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Palisade Endings Are a Constant Feature in the Extraocular Muscles of Frontal-Eyed, But Not Lateral-Eyed, Animals

Blumer, Roland; Maurer-Gesek, Barbara; Gesslbauer, Bernhard; Blumer, Michael; Pechriggl, Elisabeth; Davis López de Carrizosa, María América; Horn, Anja K.; May, Paul J.; Streicher, Johannes; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Association for Research in Vision and Ophthalmology, 2016-01-01)
Purpose To test whether palisade endings are a general feature of mammalian extraocular muscles (EOMs). Methods Thirteen ...
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Functional Diversity of Neurotrophin Actions on the Oculomotor System

Benítez Temiño, Beatriz; Davis López de Carrizosa, María América; Morcuende Fernández, Sara R.; Rodríguez Matarredona, Esperanza; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (MDPI AG, 2016-01-01)
Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance ...
PhD Thesis
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Implante de progenitores neurales en un modelo de lesión del sistema oculomotor

Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza; Rodríguez de la Cruz, Rosa María; Morado Díaz, Camilo José (2015-11-11)
El implante de células progenitoras neurales en el sistema nervioso central lesionado es una poderosa herramienta reparadora. ...
PhD Thesis
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Reacción glial tras el implante de precursores neurales en un modelo de lesión del sistema nervioso central

Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza; Talaverón Aguilocho, Rocío (2015-09-21)
En el cerebro adulto existen dos regiones con capacidad neurogénica, el giro dentado del hipocampo y la zona subventricular ...
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Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells

Talaverón Aguilocho, Rocío; Fernández, Paola; Escamilla, Rosalba; Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza; Sáez, Juan Carlos (Frontiers Research Foundation, 2015-01-01)
The postnatal subventricular zone (SVZ) lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) ...
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Neural Progenitor Cell Implants in the Lesioned Medial Longitudinal Fascicle of Adult Cats Regulate Synaptic Composition and Firing Properties of Abducens Internuclear Neurons

Morado Díaz, Camilo José; Rodríguez Matarredona, Esperanza; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2014-01-01)
Transplants of neural progenitor cells (NPCs) into the injured CNS have been proposed as a powerful tool for brain repair, ...
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Neural progenitor cell implants modulate vascular endothelial growth factor and brain-derived neurotrophic factor expression in rat axotomized neurons

Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza; Talaverón Aguilocho, Rocío; Rodríguez de la Cruz, Rosa María (2013-01-01)
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Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features

Morado Díaz, Camilo José; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; Zimmermann, Lars; Streicher, Johannes (Society for Neuroscience, 2013-01-01)
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They ...
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Evidence that the extraocular motor nuclei innervate monkey palisade endings

May, Paul J.; Zimmermann, Lars; Pastor Loro, Ángel Manuel; Streicher, Johannes (Elsevier, 2011-01-01)
Palisade endings are found in the extraocular muscles (EOMs) of almost every mammalian species, including primates. These ...
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PSA-NCAM is expressed in immature, but not recently generated, neurons in the adult cat cerebral cortex layer II

Varea Varea, Emilio; Belles, María; Vidueira, Salvador; Blasco Ibáñez, José Miguel; Crespo, Carlos; Pastor Loro, Ángel Manuel; Nacher, Juan (Frontiers Media S.A., 2011-01-01)
Neuronal production persists during adulthood in the dentate gyrus and the olfactory bulb, where substantial numbers of ...
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Dual encoding of muscle tension and eye position by abducens motoneurons

Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Miller, Joel M; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2011-01-01)
Extraocular muscle tension associated with spontaneous eye movements has a pulse-slide-step profile similar to that of ...
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The Use of PRV-Bartha to Define Premotor Inputs to Lumbar Motoneurons in the Neonatal Spinal Cord of the Mouse

Jovanovic, Ksenjia; Pastor Loro, Ángel Manuel; O'Donovan, Michael J. (Public Library of Science, 2010-01-01)
Background The neonatal mouse has become a model system for studying the locomotor function of the lumbar spinal cord. ...
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Nerve Growth Factor Regulates the Firing Patterns and Synaptic Composition of Motoneurons

Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2010-01-01)
Target-derived neurotrophins exert powerful synaptotrophic actions in the adult brain and are involved in the regulation ...
PhD Thesis
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Regulación neurotrófica de las propiedades de disparo y de la sinaptología aferente sobre las motoneuronas axotomizadas del núcleo motor ocular externo

Pastor Loro, Ángel Manuel; Davis López de Carrizosa, María América (2010-01-01)
La teoría trófica de las conexiones neuronales establece que durante el desarrollo embrionario los órganos diana son ...
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Complementary Actions of BDNF and Neurotrophin-3 on the Firing Patterns and Synaptic Composition of Motoneurons

Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Tena, Juan J.; Benítez Temiño, Beatriz; Pecero, María L.; Morcuende Fernández, Sara R.; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Society for Neuroscience, 2009-01-01)
Neurotrophins, as target-derived factors, are essential for neuronal survival during development, but during adulthood, ...
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Regulation of Gephyrin Cluster Size and Inhibitory Synaptic Currents on Renshaw Cells by Motor Axon Excitatory Inputs

González Forero, David; Pastor Loro, Ángel Manuel; Geiman, Eric J.; Benítez Temiño, Beatriz; Alvarez, Francisco J. (Society for Neuroscience, 2005-01-01)
Renshaw cells receive a high density of inhibitory synapses characterized by large postsynaptic gephyrin clusters and mixed ...
PhD Thesis
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Efectos de la reinervación de una nueva diana por neuronas centrales axotomizadas

Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María; Benítez Temiño, Beatriz (2004-01-01)
Se realizó un estudio de los efectos de un implante de primordio cerebeloso como posible nueva diana para las neuronas ...
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Recuperación de la actividad de disparo en neuronas axotomizadas mediante implante de tejido nervioso embrionario

Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (2002-01-01)
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Eye position and eye velocity integrators reside in separate brainstem nuclei.

Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María; Baker, Robert (National Academy of Sciences, 1994-01-01)
Two types of central nervous system integrators are critical for oculomotor performance. The first integrates velocity ...