NameMorcuende Fernández, Sara R.
DepartmentFisiología
Knowledge areaFisiología
Professional categoryProfesora Titular de Universidad
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  • No. publications

    16

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VEGF expression disparities in brainstem motor neurons of the SOD1GP3A ALS model: Correlations with neuronal vulnerability

Silva-Hucha, Silvia; Fernandez de Sevilla, Estrella M.; Humphreys, Kirsty M.; Benson, Fiona E.; Franco, Jaime M.; Pozo Pérez, David; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (Elsevier, 2024)
Amyotrophic lateral sclerosis (ALS) is a rare neuromuscular disease characterized by severe muscle weakness mainly due to ...
Final Degree Project
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Neurogénesis en el cerebro adulto

Villar Leveque, Laura; Morcuende Fernández, Sara R. (2022)
En los años 60 se encontraron por primera vez evidencias que apoyaban la formación de nuevas neuronas en el cerebro adulto ...
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Neuroprotective Effect of Vascular Endothelial Growth Factor on Motoneurons of the Oculomotor System

Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (MDPI, 2021)
Vascular endothelial growth factor (VEGF) was initially characterized as a potent angiogenic factor based on its activity ...
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Purinergic Receptor Blockade with Suramin Increases Survival of Postnatal Neural Progenitor Cells In Vitro

Herrera Lira, Alejandro; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez Matarredona, Esperanza (MDPI, 2021)
Neural progenitor cells (NPCs) are self-renewing and multipotent cells that persist in the postnatal and adult brain in ...
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Sources and lesion-induced changes of VEGF expression in brainstem motoneurons

Silva Hucha, Silvia; Carrero Rojas, Génova; Fernández de Sevilla, María Estrella; Benítez Temiño, Beatriz; Davis López de Carrizosa, María América; Pastor Loro, Ángel Manuel; Morcuende Fernández, Sara R. (Springer Nature, 2020)
Motoneurons of the oculomotor system show lesser vulnerability to neurodegeneration compared to other cranial motoneurons, ...
PhD Thesis
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Factor de crecimiento del endotelio vascular (VEGF) en el sistema oculomotor: presencia y modulación tras la lesión

Silva Hucha, Silvia; Morcuende Fernández, Sara R. (2020)
Estudios previos han demostrado que las motoneuronas que inervan los músculos extraoculares muestran una menor vulnerabilidad ...
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To Become or Not to Become Tumorigenic: Subventricular Zone Versus Hippocampal Neural Stem Cells

Fontán Lozano, Ángela del Carmen; Morcuende Fernández, Sara R.; Davis López de Carrizosa, María América; Benítez Temiño, Beatriz; Mejías Estévez, Rebeca María; Rodríguez Matarredona, Esperanza (Frontiers Media S.A., 2020)
Neural stem cells (NSCs) persist in the adult mammalian brain in two neurogenic regions: the subventricular zone lining ...
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Vascular Endothelial Growth Factor (VEGF) Prevents the Downregulation of the Cholinergic Phenotype in Axotomized Motoneurons of the Adult Rat

Acosta, Lourdes; Morcuende Fernández, Sara R.; Silva Hucha, Silvia; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Frontiers Media, 2018)
Vascular endothelial growth factor (VEGF) was initially characterized by its activity on the vascular system. However, ...
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Extraocular motoneurons of the adult rat show higher levels of vascular endothelial growth factor and its receptor Flk-1 than other cranial motoneurons

Silva Hucha, Silvia; Benítez Temiño, Beatriz; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María; Morcuende Fernández, Sara R.; García Hernández, Rosendo Miguel (Public Library of Science, 2017)
Recent studies show a relationship between the deficit of vascular endothelial growth factor (VEGF) and motoneuronal ...
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Extraocular Motor System Exhibits a Higher Expression of Neurotrophins When Compared with Other Brainstem Motor Systems

García Hernández, Rosendo Miguel; Silva Hucha, Silvia; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel; Benítez Temiño, Beatriz (Frontiers Media, 2017)
Extraocular motoneurons resist degeneration in diseases such as amyotrophic lateral sclerosis. The main objective of the ...
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Functional Diversity of Neurotrophin Actions on the Oculomotor System

Benítez Temiño, Beatriz; Davis López de Carrizosa, María América; Morcuende Fernández, Sara R.; Rodríguez Matarredona, Esperanza; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (MDPI AG, 2016)
Neurotrophins play a principal role in neuronal survival and differentiation during development, but also in the maintenance ...
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Neural Progenitor Cell Implants in the Lesioned Medial Longitudinal Fascicle of Adult Cats Regulate Synaptic Composition and Firing Properties of Abducens Internuclear Neurons

Morado Díaz, Camilo José; Rodríguez Matarredona, Esperanza; Morcuende Fernández, Sara R.; Talaverón Aguilocho, Rocío; Davis López de Carrizosa, María América; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2014)
Transplants of neural progenitor cells (NPCs) into the injured CNS have been proposed as a powerful tool for brain repair, ...
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Differential regulation of the expression of neurotrophin receptors in rat extraocular motoneurons after lesion

Morcuende Fernández, Sara R.; Rodríguez Matarredona, Esperanza; Benítez Temiño, Beatriz; Muñoz Hernández, Rocío; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Wiley, 2011)
Neurotrophins acting through high-affinity tyrosine kinase receptors (trkA, trkB, and trkC) play a crucial role in regulating ...
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Nerve Growth Factor Regulates the Firing Patterns and Synaptic Composition of Motoneurons

Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Morcuende Fernández, Sara R.; Rodríguez de la Cruz, Rosa María; Pastor Loro, Ángel Manuel (Society for Neuroscience, 2010)
Target-derived neurotrophins exert powerful synaptotrophic actions in the adult brain and are involved in the regulation ...
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Complementary Actions of BDNF and Neurotrophin-3 on the Firing Patterns and Synaptic Composition of Motoneurons

Davis López de Carrizosa, María América; Morado Díaz, Camilo José; Tena, Juan J.; Benítez Temiño, Beatriz; Pecero, María L.; Morcuende Fernández, Sara R.; Pastor Loro, Ángel Manuel; Rodríguez de la Cruz, Rosa María (Society for Neuroscience, 2009)
Neurotrophins, as target-derived factors, are essential for neuronal survival during development, but during adulthood, ...
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Neuronal Premotor Networks Involved in Eyelid Responses: Retrograde Transneuronal Tracing with Rabies Virus from the Orbicularis Oculi Muscle in the Rat

Morcuende Fernández, Sara R.; Delgado García, José María; Ugolini, Gabriella (Society for Neuroscience, 2002)
Retrograde transneuronal tracing with rabies virus from the right orbicularis oculi muscle was used to identify neural ...