NameGarcía Rondón, Ana
DepartmentGenética
Knowledge areaGenética
Professional categoryProfesora Titular de Universidad
E-mailRequest
         
  • No. publications

    13

  • No. visits

    2511

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    2473


 

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Rat1 promotes premature transcription termination at R-loops

Mérida Cerro, José Antonio; Maraver-Cárdenas, Pablo; García Rondón, Ana; Aguilera López, Andrés (Oxford University Press, 2024)
Certain DNA sequences can adopt a non-B form in the genome that interfere with DNA-templated processes, including ...
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Dna-rna hybrids at dsbs interfere with repair by homologous recombination

Ortega Moreno, Pedro; Mérida Cerro, José Antonio; García Rondón, Ana; Gómez González, Belén; Aguilera López, Andrés (eLife Sciences Publications, 2021)
DNA double-strand breaks (DSBs) are the most harmful DNA lesions and their repair is crucial for cell viability and genome ...
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Histone H3E73Q and H4E53A mutations cause recombinogenic DNA damage

Ortega Moreno, Pedro; García Pichardo, Desiré; San Martín Alonso, Marta; García Rondón, Ana; Gómez González, Belén; Aguilera López, Andrés (Shared Science Publishers OG, 2020)
The stability and function of eukaryotic genomes is closely linked to histones and to chromatin structure. The state of ...
PhD Thesis
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New factors involved in transcription-associated genome instability

Mérida Cerro, José Antonio; Aguilera López, Andrés; García Rondón, Ana (2019)
El mantenimiento de la integridad del DNA y la transmisión fiel de su información a la descendencia es una prioridad para ...
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What causes an RNA-DNA hybrid to compromise genome integrity?

García Rondón, Ana; Aguilera López, Andrés (Elsevier, 2019)
Transcription is a source of genome instability that stimulates mutation and recombination. Part of the damage produced ...
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Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability

Salas Armenteros, Irene; Barroso Ceballos, Sonia Inés; García Rondón, Ana; Pérez Calero, Mónica; Andújar, Eloísa; Luna Varo, Rosa María; Aguilera López, Andrés (Elsevier, 2019)
THO/TREX is a conserved complex with a role in messenger ribonucleoprotein biogenesis that links gene expression and genome ...
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The THO Complex as a Paradigm for the Prevention of Cotranscriptional R-Loops

Luna Varo, Rosa María; García Rondón, Ana; Pérez Calero, Carmen; Salas Armenteros, Irene; Aguilera López, Andrés (Cold Spring Harbor Laboratory Press, 2019)
Different proteins associate with the nascent RNA and the RNA polymerase (RNAP) to catalyze the transcription cycle and ...
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Yra1-bound RNA–DNA hybrids cause orientation-independent transcription– replication collisions and telomere instability

García Rubio, María Luisa; Aguilera, Paula; Lafuente Barquero, Juan; Ruiz, José F.; Simon, Marie-Noelle; Geli, Vincent; García Rondón, Ana; Aguilera López, Andrés (Cold Spring Harbor Laboratory Press, 2018)
R loops are an important source of genome instability, largely due to their negative impact on replication progression. ...
PhD Thesis
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Papel de la cromatina en la formación de R-loops

García Pichardo, Desiré; García Rondón, Ana; Aguilera López, Andrés (2017)
La inestabilidad genómica es una patología celular asociada a múltiples enfermedades genéticas, incluido el cáncer (Aguilera ...
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Histone Mutants Separate R Loop Formation from Genome Instability Induction

García Pichardo, Desiré; Cañas, Juan C.; García Rubio, María Luisa; Gómez González, Belén; García Rondón, Ana; Aguilera López, Andrés (Elsevier, 2017)
R loops have positive physiological roles, but they can also be deleterious by causing genome instability, and the mechanisms ...
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Yeast Sen1 helicase protects the genome from transcription-associated instability

Mischo, Hannah E.; Gómez González, Belén; Grzechnik, Pawel; García Rondón, Ana; Wei, Wu; Steinmetz, Lars; Aguilera López, Andrés; Proudfoot, Nick J. (Elsevier, 2011)
Sen1 of S. cerevisiae is a known component of the NRD complex implicated in transcription termination of nonpolyadenylated ...
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Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation

García Rondón, Ana; Jimeno González, Sonia; García Rubio, María Luisa; Aguilera López, Andrés (American Society for Biochemistry and Molecular Biology Inc., 2003)
THO/TREX is a conserved eukaryotic complex formed by the core THO complex plus proteins involved in mRNA metabolism and ...
PhD Thesis
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Elongación de la transcripción en S. cerevisiae el complejo THO y factores relacionados funcionalmente

García Rondón, Ana; Aguilera López, Andrés (2003)
La transcripción es el proceso por el cual se copia la información contenida en el DNA, a una molécula de RNA. Se divide ...