NameEchevarría Irusta, Miriam
DepartmentFisiología Médica y Biofísica
Knowledge areaFisiología
Professional categoryCatedrática de Universidad
E-mailRequest
           
  • No. publications

    27

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Special Issue “Aquaporins in Brain Disease”

Echevarría Irusta, Miriam; García Miranda, Pablo (Multidisciplinary Digital Publishing Institute (MDPI), 2024)
PhD Thesis
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Implicación de acuaporina-4 en las bases celulares y moleculares del desarrollo postnatal del sistema nervioso central murino

Mayo Leon, Francisco; Echevarría Irusta, Miriam; Ramírez Lorca, Reposo (2023)
El agua es un elemento básico en la fisiología de los seres vivos. A escala celular, su transporte se encuentra facilitado ...
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Generation of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated by Mesenchymal Stem Cell Therapy

García Bonilla, María; Ojeda Pérez, Betsaida; Shumilov, Kirill; Rodríguez-Pérez, Luis Manuel; Vitorica Ferrández, Francisco Javier; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam; Páez González, Patricia; Jiménez, Antonio J. (MDPI AG, 2023)
Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. ...
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Aquaporin-4 expression switches from white to gray matter regions during postnatal development of the central nervous system

Mayo Leon, Francisco; Gonzalez Vinceiro, Lourdes; Hiraldo González, Laura; Calle-Castillejo, Claudia; Morales-Álvarez, Sara; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (MDPI, 2023)
Aquaporin-4 (AQP4) is the most abundant water channel in the central nervous system and plays a fundamental role in ...
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Cellular distribution of brain aquaporins and their contribution to cerebrospinal fluid homeostasis and hydrocephalus

Trillo Contreras, José Luis; Ramírez Lorca, Reposo; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (MDPI, 2022)
Brain aquaporins facilitate the movement of water between the four water compartments: blood, cerebrospinal fluid, ...
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Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus

Trillo Contreras, José Luis; Toledo Aral, Juan José; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (MDPI, 2021)
Aquaporin-4 (AQP4) is the principal water channel in the brain being expressed in astrocytes and ependymal cells. AQP4 ...
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Aquaporin-4 removal from the plasma membrane of human muller cells by AQP4-IgG from patients with neuromyelitis optica induces changes in cell volume homeostasis: the first step of retinal injury?

Netti, Vanina; Fernández, Juan; Melamud, Luciana; García Miranda, Pablo; Di Giusto, Gisela; Ford, Paula; Echevarría Irusta, Miriam; Capurro, Claudia (Springer, 2021)
Aquaporin-4 (AQP4) is the target of the specifc immunoglobulin G autoantibody (AQP4-IgG) produced in patients with neuromyelitis ...
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Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus

Hiraldo González, Laura; Trillo Contreras, José Luis; García Miranda, Pablo; Pineda Sánchez, Rocío; Ramírez Lorca, Reposo; Rodrigo Herrero, Silvia; Olivares Blanco, Magdalena; Oliver, María; Bernal, María; Franco Macías, Emilio; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (PLOS, 2021)
Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin ...
PhD Thesis
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Contribución de las acuaporinas cerebrales a la homeostasis del líquido cefalorraquídeo y su papel en el desarrollo de la hidrocefalia asociada a hipoxia y envejecimiento

Trillo Contreras, José Luis; Echevarría Irusta, Miriam; Villadiego Luque, Francisco Javier (2020)
Las acuaporinas son una familia de pequeñas proteínas integrales de membrana (≈ 30 kDa) que se expresan ampliamente en el ...
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Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders

García Miranda, Pablo; Morón Civanto, Francisco Jesús; Martínez Olivo, María del Mar; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Lebrato-Hernández, Lucía; Lamas-Pérez, Lucía; Navarro, Gemma; Abril-Jaramillo, Javier; García Sánchez, María Isabel; Casado Chocán, José Luis; Uclés Sánchez, Antonio José; Romera, Mercedes; Echevarría Irusta, Miriam; Díaz Sánchez, María (MDPI, 2019)
The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically ...
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AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis

Trillo Contreras, José Luis; Toledo Aral, Juan José; Echevarría Irusta, Miriam; Villadiego Luque, Francisco Javier (MDPI, 2019)
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells ...
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Expression Pattern of Aquaporin 1 and Aquaporin 3 in Melanocytic and Nonmelanocytic Skin Tumors

Osorio, Giovana; Zulueta-Dorado, Teresa; González Rodríguez, Patricia; Bernabéu-Wittel, José; Conejo-Mir Sánchez, Julián; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (American journal of clinical pathology, 2019)
Objectives: Study of aquaporin 1 (AQP1) and aquaporin 3 (AQP3) expression to understand its potential role in the ...
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The Expression of AQP1 IS Modified in Lung of Patients With Idiopathic Pulmonary Fibrosis: Addressing a Possible New Target

Galán-Cobo, Ana; Arellano Orden, Elena; Sánchez Silva, Rocío; López-Campos Bodineau, José Luis; Gutiérrez Rivera, César; Echevarría Irusta, Miriam (Frontiers Research Foundation, 2018)
Activation of the epithelial-mesenchymal transition process (EMT) by which alveolar cells in human lung tissue undergo ...
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Combined effects of aquaporin-4 and hypoxia produce age-related hydrocephalus

Trillo Contreras, José Luis; Ramírez Lorca, Reposo; Hiraldo González, Laura; Sánchez Gomar, Ismael; Galán-Cobo, Ana; Suárez-Luna, Nela; Sánchez de Rojas de Pedro, Eva; Toledo Aral, Juan José; Villadiego Luque, Francisco Javier; Echevarría Irusta, Miriam (Elsevier, 2018)
Aquaporin-4, present in ependymal cells, in glia limiting and abundantly in pericapillary astrocyte foot pro cesses, and ...
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Long-term immunosuppression for CNS mouse xenotransplantation: Effects on nigrostriatal neurodegeneration and neuroprotective carotid body cell therapy

Villadiego Luque, Francisco Javier; Romo-Madero, Sonia; García-Swinburn, Roberto; Suárez-Luna, Nela; Bermejo-Navas, Alfonso; Echevarría Irusta, Miriam; Toledo Aral, Juan José (Wiley, 2018)
Abstract Background: The use of long-term immunosuppressive treatments on neural trans plantation has been controversial ...
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Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders

Sánchez Gomar, Ismael; Díaz Sánchez, María; Uclés Sánchez, Antonio José; Casado Chocán, José Luis; Suárez-Luna, Nela; Ramírez Lorca, Reposo; Villadiego Luque, Francisco Javier; Toledo Aral, Juan José; Echevarría Irusta, Miriam (MDPI AG, 2016)
Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has ...
PhD Thesis
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Acuaporinas en diversas patologías neurológicas

Sánchez Gomar, Ismael; Echevarría Irusta, Miriam (2016)
El agua es un compuesto esencial para la vida. La mayoría de las moléculas (iones, azúcares, proteínas, etc.) que forman ...
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Role of aquaporins in cell proliferation: What else beyond water permeability?

Galán-Cobo, Ana; Ramírez Lorca, Reposo; Echevarría Irusta, Miriam (Taylor & Francis Open Access, 2016)
In addition to the extensive data demonstrating the importance of mammalian AQPs for the movement of water and some small ...
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Overexpression of AQP3 Modifies the Cell Cycle and the Proliferation Rate of Mammalian Cells in Culture

Galán-Cobo, Ana; Ramírez Lorca, Reposo; Serna, Ana; Echevarría Irusta, Miriam (PUBLIC LIBRARY SCIENCE, 2015)
Abnormal AQP3 overexpression in tumor cells of different origins has been reported and a role for this enhanced AQP3 ...
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Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound

Martins, Ana Paula; Marrone, Alessandro; Ciancetta, Antonella; Galán-Cobo, Ana; Echevarría Irusta, Miriam; Moura, Teresa F.; Soveral, Graça (Public Library of Science, 2012)
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many ...
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Overexpression of aquaporin-1 in lung adenocarcinomas and pleural mesotheliomas

López-Campos Bodineau, José Luis; Sánchez Silva, Rocío; Gómez Izquierdo, Lourdes; Márquez, Eduardo; Ortega Ruiz, Francisco; Cejudo Ramos, Pilar; Barrot Cortés, Emilia; Toledo Aral, Juan José; Echevarría Irusta, Miriam (2011)
Aquaporin-1 (AQP1) is the main water channel responsible for water transport through many epithelia and endothelia. The ...
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Functional and transcriptional induction of Aquaporin-1 gene by hypoxia; analysis of promoter and role of Hif-1α

Abreu Rodríguez, Irene; Sánchez Silva, Rocío; Martins, Ana Paula; Soveral, Graça; Toledo Aral, Juan José; López Barneo, José; Echevarría Irusta, Miriam (2011)
Aquaporin-1 (AQP1) is a water channel that is highly expressed in tissues with rapid O2 transport. It has been reported ...
PhD Thesis
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Quimiorrecepción del CO2 en la médula adrenal y facilitación de la permeabilidad a O2 por la acuaporina-1

Muñoz Cabello, Ana María; Echevarría Irusta, Miriam; López Barneo, José; Toledo Aral, Juan José (2007)
El desarrollo de esta Tesis se ha centrado en el estudio de los mecanismos celulares que permiten la quimiotransducción ...
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Development of cytosolic hypoxia and hypoxia-inducible factor stabilization are facilitated by aquaporin-1 expression

Echevarría Irusta, Miriam; Muñoz Cabello, Ana María; Sánchez Silva, Rocío; Toledo Aral, Juan José; López Barneo, José (Elsevier, 2007)
O2 is essential for aerobic life, and the classic view is that it diffuses freely across the plasma membrane. However, ...
PhD Thesis
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Neuroprotección en un nuevo modelo de animal transgénico

Mejías Estévez, Rebeca María; Echevarría Irusta, Miriam; López Barneo, José (2006)
El objetivo general de este proyecto fue analizar en un modelo de parkinsonismo experimental en ratones, si el aumento del ...
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Rat Adrenal Chromaffin Cells Are Neonatal CO2 Sensors

Muñoz Cabello, Ana María; Toledo Aral, Juan José; López Barneo, José; Echevarría Irusta, Miriam (2005)
We studied the participation of adrenal medulla (AM) chromaffin cells in hypercapnic chemotransduction. Using amperometric ...
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Trophic restoration of the nigrostriatal dopaminergic pathway in long-term carotid body-grafted parkinsonian rats

Toledo Aral, Juan José; Méndez Ferrer, Simón; Pardal Redondo, Ricardo; Echevarría Irusta, Miriam; López Barneo, José (2003)
We studied the mechanisms underlying long-term functional recovery of hemiparkinsonian rats grafted intrastriatally with ...