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idUS celebra 10 años
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Más de 3.000 aportaciones de sexenios en idUS
Estas aportaciones depositadas en el repositorio permiten el cumplimiento de los requisitos de la convocatoria de ANECA.
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Abrimos idUS a una nueva etapa
Potenciamos la Ciencia Abierta con un repositorio más fácil de consultar.
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idUS ofrece estadísticas más visuales
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Envíos recientes
Polyurethane Foam Degradation Combining Ozonization and Mealworm Biodegradation and its Exploitation
(Springer, 2025) Ros, Margarita; Carrascosa, Ángel; Muñoz, Marta; Navarro, Maria Virtudes; Orts Gómez, José María; Pascual, Jose Antonio; Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular; Ministerio de Ciencia e Innovación (MICIN). España
The biodegradation of polyurethane foam (PU foam) using a combination of oxidative pre-treatment (ozonization) and Tenebrio molitor (T. molitor) mealworms was conducted in this study. Different degrees of ozone oxidation (0%, 25%, and 50%) were applied to PU foam, which was subsequently fed to mealworms. The mealworms’ survival and growth were then compared to mealworms receiving a normal diet (bran). Results showed that mealworms fed with non-oxidized PU foam (PUF0) exhibited a higher consumption rate (11.8%) than those fed with 25% (PUF25) and 50% (PUF50) oxidized PU foam (7.7% and 5.7%, respectively). The survival rate was similar across all the PU foam diets and the bran diet. Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC) analyses revealed minor structural changes in the PU foam. The gut microbiota analysis showed a significant correlation between the PU foam and bran diets. Among the different oxidized PU, distinct microbial community profiles were also observed, with the genus Klebsiella consistently present across the PU foam diets. The ozone pre-treatment altered the palatability and degradation of the PU foam by mealworms, while the mealworm frass and chitin obtained could potentially be used as resources for agricultural and industrial applications that would close the circular bio-economy cycle.
Different discourse practices framing different realities: A Discursive Psychology approach to Princess Diana
(2023) Lomelino Rodríguez, Cristina; Íñigo Mora, Isabel María; Universidad de Sevilla. Departamento de Filología Inglesa (Lengua Inglesa)
Editorial: 15 years of Frontiers in Cellular Neuroscience: the dual role of microglia in (neuro)inflammation
(Frontiers Media, 2025) Herrera Carmona, Antonio José; Universidad de Sevilla. Departamento de Bioquímica y Biología Molecular
Phototropin connects blue light perception to starch metabolism in green algae
(Springer Nature, 2025-03-15) Yuan, Yizhong; Iannetta, Anthony A.; Kim, Minjae; Sadecki, Patric W.; Arend, Marius; Tsichla, Angeliki; Ruiz Sola, M. Águila; Kepesidis, Georgios; Petroutsos, Dimitris; Universidad de Sevilla. Departamento de Bioquímica Vegetal y Biología Molecular; Human Frontiers Science Program; rench National Research Agency
In photosynthetic organisms, light acts as an environmental signal to control their development and physiology, as well as energy source to drive the conversion of CO2 into carbohydrates used for growth or storage. The main storage carbohydrate in green algae is starch, which accumulates during the day and is broken down at night to meet cellular energy demands. The signaling role of light quality in the regulation of starch accumulation remains unexplored. Here, we identify PHOTOTROPIN-MEDIATED SIGNALING KINASE 1 (PMSK1) as a key regulator of starch metabolism in Chlamydomonas reinhardtii. In its phosphorylated form (PMSK1-P), it activates GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (GAP1), promoting starch biosynthesis. We show that blue light, perceived by PHOTOTROPIN, induces PMSK1 dephosphorylation that in turn represses GAP1 mRNA levels and reduces starch accumulation. These findings reveal a previously uncharacterized blue light-mediated signaling pathway that advances our understanding of photoreceptor-controlled carbon metabolism in microalgae.
Response to Bile Salts in Clinical Strains of Acinetobacter baumannii Lacking the AdeABC Efflux Pump: Virulence Associated with Quorum Sensing
(Frontiers Media, 2017-05-09) López, María; Blasco, Lucía; Gato, Eva; Pérez, Astrid; Fernández García, Laura; Martínez Martínez, Luis; Rodríguez-Baño, Jesús; Pascual Hernández, Álvaro; Garnacho Montero, José; Pachón Díaz, Jerónimo; Cisneros, José Miguel; Universidad de Sevilla. Departamento de Microbiología; Universidad de Sevilla. Departamento de Medicina
Introduction: Acinetobacter baumannii is an opportunistic nosocomial pathogen associated with multiple infections. This pathogen usually colonizes (first stage of microbial infection) host tissues that are in contact with the external environment. As one of the sites of entry in human hosts is the gastrointestinal tract, the pathogen must be capable of tolerating bile salts. However, studies analyzing the molecular characteristics involved in the response to bile salts in clinical strains of A. baumannii are scarce.
Material and Methods: Microbiological and transcriptional studies (arrays and RT-PCR) in the response to bile salts were carried out in isogenic (A. baumanni ΔadeB ATCC 17978 and A. baumannii ΔadeL ATCC 17978) and clinical strains from clone ST79/PFGE-HUI-1 which is characterized by lacking the AdeABC efflux pump and by overexpression the AdeFGH efflux pump.
Results and Discussion: In presence of bile salts, in addition to the glutamate/aspartate transporter were found overexpressed in A. baumannii ΔadeB ATCC 17978, the virulence factors (surface motility, biofilm, and Type VI Secretion System) which are associated with activation of the Quorum Sensing system. Overexpression of these factors was confirmed in clinical strains of clone ST79/PFGE-HUI-1.
Conclusions: This the first study about the adaptive response to bile salts investigating the molecular and microbiological characteristics in response to bile salts of an isogenic model of A. baumannii ATCC 17978 and clinical isolates of A. baumannii (clinical strains of ST79/PFGE-HUI-1) lacking the main RND efflux pump (AdeABC). Clinical isolates of A. baumannii lacking the AdeABC efflux pump (clone ST79/PFGE-HUI-1) displayed a new clinical profile (increased invasiveness) possibly associated with the response to stress conditions (such as the presence of bile salts).
