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Mostrando ítems 11-20 de 20
Artículo
Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus
(MDPI, 2021-09-09)
Aquaporin-4 (AQP4) is the principal water channel in the brain being expressed in astrocytes and ependymal cells. AQP4 plays an important role in cerebrospinal fluid (CSF) homeostasis, and alterations in its expression ...
Artículo
Artículo
Immunization with α-synuclein/Grp94 reshapes peripheral immunity and suppresses microgliosis in a chronic parkinsonism model
(Wiley, 2018)
Neuroinflammation mediated by chronically activated microglia, largely caused by abnormal accumulation of misfolded α-synuclein (αSyn) protein, is known to contribute to the pathophysiology of Parkinson’s disease (PD). In ...
Artículo
Evaluation of aquaporins in the cerebrospinal fluid in patients with idiopathic normal pressure hydrocephalus
(PLOS, 2021)
Brain aquaporin 1 (AQP1) and AQP4 are involved in cerebrospinal fluid (CSF) homeostasis and might participate in the origin of hydrocephalus. Studies have shown alterations of perivascular AQP4 expression in idiopathic ...
Artículo
AQP1 and AQP4 Contribution to Cerebrospinal Fluid Homeostasis
(MDPI, 2019-02-24)
Aquaporin 1 (AQP1), expressed in epithelial cells of the choroid plexus, and aquaporin 4 (AQP4) present in ependymal cells and glia limitants have been proposed to play a significant role in cerebrospinal fluid (CSF) ...
Tesis Doctoral
Contribución de las acuaporinas cerebrales a la homeostasis del líquido cefalorraquídeo y su papel en el desarrollo de la hidrocefalia asociada a hipoxia y envejecimiento
(2020-10-07)
Las acuaporinas son una familia de pequeñas proteínas integrales de membrana (≈ 30 kDa) que se expresan ampliamente en el cuerpo. Tradicionalmente se las han definido como facilitadores del transporte pasivo de agua a ...
Capítulo de Libro
Carotid Body Transplants as a Therapy for Parkinson’s Disease
(The Royal Society of Chemistry, 2013)
Affecting over 1.5 million people across the world, Parkinson's disease is a progressive neurological condition characterized, in part, by the loss of dopaminergic neurons in the substantia nigra pars compacta. It affects ...
Artículo
Long-term immunosuppression for CNS mouse xenotransplantation: Effects on nigrostriatal neurodegeneration and neuroprotective carotid body cell therapy
(Wiley, 2018)
Abstract Background: The use of long-term immunosuppressive treatments on neural trans plantation has been controversial during the last decades. Although nowadays there is a consensus about the necessity of maintaining ...
Artículo
Comparative analysis for the presence of IgG anti-aquaporin-1 in patients with NMO-Spectrum disorders
(MDPI AG, 2016-07-23)
Detection of IgG anti-Aquaporin-4 (AQP4) in serum of patients with Neuromyelitis optica syndrome disorders (NMOSD) has improved diagnosis of these processes and differentiation from Multiple sclerosis (MS). Recent findings ...
Artículo
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
(CELL PRESS (Elsevier), 2022)
The autonomic nervous system is a master regulator of homeostatic processes and stress responses. Sym pathetic noradrenergic nerve fibers decrease bone mass, but the role of cholinergic signaling in bone has remained ...