Perfil del autor: Florencio Bellido, Francisco Javier
Datos institucionales
| Nombre | Florencio Bellido, Francisco Javier |
| Departamento | Bioquímica Vegetal y Biología Molecular |
| Área de conocimiento | Bioquímica y Biología Molecular |
| Categoría profesional | Catedrático de Universidad |
| Correo electrónico | Solicitar |
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Estadísticas
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Nº publicaciones
76
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Nº visitas
10151
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Nº descargas
17471
| Publicaciones |
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Artículo
 Stress response requires an efficient connection between glycogen and central carbon metabolism by phosphoglucomutases in cyanobacteria
(Oxford University Press, 2023)
Glycogen and starch are the main storage polysaccharides, acting as a source of carbon and energy when necessary. ... |
Artículo
Extracellular vesicles as an alternative copper-secretion mechanism in bacteria
(Elsevier, 2022)
Metal homeostasis is fundamental for optimal performance of cell metabolic pathways. Over the course of evolution, several ... |
Artículo
Back to the future: Transplanting the chloroplast TrxF–FBPase–SBPase redox system to cyanobacteria
(Frontiers Media S.A., 2022)
Fructose-1,6-bisphosphatase (FBPase) and sedoheptulose-1,7-bisphosphatase (SBPase) are two essential activities in the ... |
Artículo
Exploring the Diversity of the Thioredoxin Systems in Cyanobacteria
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Cyanobacteria evolved the ability to perform oxygenic photosynthesis using light energy to reduce CO2 from electrons ... |
Artículo
The sRNA NsiR4 fine-tunes arginine synthesis in the cyanobacterium Synechocystis sp. PCC 6803 by post-transcriptional regulation of PirA
(Taylor & Francis, 2022)
As the only oxygenic phototrophs among prokaryotes, cyanobacteria employ intricate mechanisms to regulate common metabolic ... |
Tesis Doctoral
Control redox de la percepción de metales y del metabolismo del carbono en cianobacterias
(2021)
Las cianobacterias son organismos procariotas capaces de realizar la fotosíntesis oxigénica de forma similar a las plantas ... |
Artículo
 A protease-mediated mechanism regulates the cytochrome c6/plastocyanin switch in Synechocystis sp. PCC 6803
(NAS, 2021)
After the Great Oxidation Event (GOE), iron availability was greatly decreased, and photosynthetic organisms evolved several ... |
Artículo
The Novel PII-Interacting Protein PirA Controls Flux into the Cyanobacterial Ornithine-Ammonia Cycle
(American Society for Microbiology, 2021)
Among prokaryotes, cyanobacteria have an exclusive position as they perform oxygenic photosynthesis. Cyanobacteria ... |
Artículo
Depletion of m-type thioredoxin impairs photosynthesis, carbon fixation, and oxidative stress in cyanobacteria
(Oxford University Press, 2021)
Thioredoxins (Trxs) are disulfide oxidoreductases that regulate many biological processes. The m-type thioredoxin (TrxA) ... |
Tesis Doctoral
Esencialidad de la tiorredoxina TrxA en cianobacterias. Estudio de un mutante condicional en Synechocystis sp. PCC 6803
(2020)
Introducción: el cáncer de cabeza y cuello (CCC) constituye la novena neoplasia maligna más común en el mundo, con una ... |
Artículo
CfrA, a novel carbon flow regulator, adapts carbon metabolism to nitrogen deficiency in cyanobacteria
(American Society of Plant Biologists, 2020)
Cyanobacteria unable to fix atmospheric nitrogen have evolved sophisticated adaptations to survive to long periods of ... |
Artículo
Dynamics of the Intrinsically Disordered Inhibitor IF7 of Glutamine Synthetase in Isolation and in Complex with its Partner
(Elsevier, 2020)
Glutamine synthetase (GS) catalyzes the ATP-dependent formation of glutamine from glutamate and ammonia. The activity of ... |
Artículo
Lethality caused by ADP-glucose accumulation is suppressed by salt-induced carbon flux redirection in cyanobacteria
(Oxford University Press, 2020)
Cyanobacteria are widely distributed photosynthetic organisms. During the day they store carbon, mainly as glycogen, to ... |
Artículo
Redox interference in nitrogen status via oxidative stress is mediated by 2-oxoglutarate in cyanobacteria
(Wiley-Blackwell, 2019)
Reactive oxygen species (ROS) are generated naturally in photosynthetic organisms by respiration and photosynthesis. ... |
Artículo
The Distinctive Regulation of Cyanobacterial Glutamine Synthetase
(MDPI AG, 2018)
Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable ... |
Artículo
The cyanobacterial ribosomal-associated protein LrtA from Synechocystis sp. PCC 6803 is an oligomeric protein in solution with chameleonic sequence properties
(MDPI, 2018)
The LrtA protein of Synechocystis sp. PCC 6803 intervenes in cyanobacterial post-stress survival and in stabilizing 70S ... |
Artículo
Characterization of TrxC, an Atypical Thioredoxin Exclusively Present in Cyanobacteria
(MDPI, 2018)
Cyanobacteria form a diverse group of oxygenic photosynthetic prokaryotes considered to be the antecessor of plant ... |
Tesis Doctoral
Interacción entre el estado redox celular y el metabolismo del nitrógeno en cianobacterias
(2017)
En este trabajo se pretende analizar cómo el estrés oxidativo interfiere con el metabolismo del nitrógeno y su regulación ... |
Artículo
A new member of the thioredoxin reductase family from early uxygenic photosynthetic organisms
(Oxford University Press, 2017)
Thioredoxins (Trxs) are key components of the redox system that regulates the activity of a spectrum of target proteins ... |
Artículo
Identification of the direct regulon of NtcA during early acclimation to nitrogen starvation in the cyanobacterium Synechocystis sp. PCC 6803
(Oxford University Press, 2017)
In cyanobacteria, nitrogen homeostasis is maintained by an intricate regulatory network around transcription factor NtcA. ... |
Artículo
Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase
(National Academy of Sciences, 2017)
Flavoproteinsparticipateinawidevarietyofphysiologicallyrelevant processes that typically involve redox reactions. Within ... |
Artículo
Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values
(Wiley-Blackwell, 2017)
The sequential action of glutamine synthetase (GS) and glutamate synthase (GOGAT) in cyanobacteria allows the incorporation ... |
| Tesis Doctoral |
Artículo
The cyanobacterial ribosomal-associated protein LrtA is involved in post-stress survival in synechocystis sp. PCC 6803
(Public Library of Science, 2016)
A light-repressed transcript encodes the LrtA protein in cyanobacteria. We show that halflife of lrtA transcript from ... |
Artículo
NADPH-thioredoxin reductase c mediates the response to oxidative stress and thermotolerance in the cyanobacterium anabaena sp. pcc7120
(Frontiers Media S.A., 2016)
NADPH-thioredoxin reductase C (NTRC) is a bimodular enzyme composed of an NADPH-thioredoxin reductase and a thiioredoxin ... |
Artículo
Characterization of function of the GlgA2 glycogen/starch synthase in Cyanobacterium sp. Clg1 highlights convergent evolution of glycogen metabolism into starch granule aggregation
(American Society of Plant Biologists, 2016)
At variance with the starch-accumulating plants and most of the glycogen-accumulating cyanobacteria, Cyanobacterium sp. ... |
Artículo
A loop unique to ferredoxin-dependent glutamate synthases is not absolutely essential for ferredoxin-dependent catalytic activity
(Springer, 2015)
It had been proposed that a loop, typically containing 26 or 27 amino acids, which is only present in monomeric, ... |
Artículo
A core of three amino acids at the carboxyl-terminal region of glutamine synthetase defines its regulation in cyanobacteria
(Wiley, 2015)
Glutamine synthetase (GS) type I is a key enzyme in nitrogen metabolism, and its activity is finely controlled by cellular ... |
Artículo
CopM is a novel copper-binding protein involved in copper resistance in Synechocystis sp. PCC 6803
(Wiley Open Access, 2015)
Copper resistance system in the cyanobacterium Synechocystis sp. PCC 6803 comprises two operons, copMRS and copBAC, which ... |
Artículo
Genomic responses to arsenic in the cyanobacterium Synechocystis sp. PCC 6803
(Public Library of Science, 2014)
Arsenic is a ubiquitous contaminant and a toxic metalloid which presents two main redox states in nature: arsenite [AsIII] ... |
Artículo
Global transcriptional profiles of the copper responses in the cyanobacterium synechocystis sp. PCC 6803
(Public Library of Science, 2014)
Copper is an essential element involved in fundamental processes like respiration and photosynthesis. However, it becomes ... |
Artículo
Proteomic pattern alterations of the cyanobacterium Synechocystis sp. PCC 6803 in response to cadmium, nickel and cobalt
(Elsevier, 2014)
Cyanobacteria represent the largest and most diverse group of prokaryotes capable of performing oxygenic photosynthesis ... |
Artículo
Redox regulation of glycogen biosynthesis in the cyanobacterium synechocystis sp. PCC 6803: Analysis of the AGP and glycogen synthases
(Oxford University Press, 2014)
Glycogen constitutes the major carbon storage source in cyanobacteria, as starch in algae and higher plants. Glycogen and ... |
Artículo
Metals in Cyanobacteria: Analysis of the Copper, Nickel, Cobalt and Arsenic Homeostasis Mechanisms
(MDPI AG, 2014)
Traces of metal are required for fundamental biochemical processes, such as photosynthesis and respiration. Cyanobacteria ... |
Artículo
Glutaredoxins are essential for stress adaptation in the cyanobacterium Synechocystis sp. PCC 6803
(Frontiers media, 2013)
Glutaredoxins are small redox proteins able to reduce disulfides and mixed disulfides between GSH and proteins. Synechocystis ... |
Artículo
Redox control of copper homeostasis in cyanobacteria
(Taylor & Francis, 2012)
Copper is essential for all living organisms but is toxic when present in excess. Therefore organisms have developed ... |
Artículo
Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas
(American Society of Plant Biologists, 2011)
The target of rapamycin (TOR) kinase integrates nutritional and stress signals to coordinately control cell growth in all ... |
| Artículo |
Artículo
A comparative analysis of the NADPH thioredoxin reductase C-2-Cys peroxiredoxin system from plants and Cyanobacteria
(American Society of Plant Biologists, 2011)
Redox regulation based on disulfide-dithiol conversion catalyzed by thioredoxins is an important component of chloroplast ... |
| Tesis Doctoral |
| Tesis Doctoral |
Tesis Doctoral
Producción fotosintética de etanol por la cianobacteria Synechocystis sp. PCC 6803
(2010)
La preocupación en el ámbito mundial por el calentamiento del planeta, unida al agotamiento de las reservas de petróleo ... |
Artículo
Posttranscriptional regulation of glutamine synthetase in the filamentous cyanobacterium Anabaena sp. PCC 7120: Differential expression between vegetative cells and heterocysts
(American Society for Microbiology, 2010)
Genes homologous to those implicated in glutamine synthetase (GS) regulation by protein-protein interaction in the ... |
Artículo
Overoxidation of 2-cys peroxiredoxin in prokaryotes: Cyanobacterial 2-cys peroxiredoxins sensitive to oxidative stress
(Elsevier, 2010)
In eukaryotic organisms, hydrogen peroxide has a dual effect; it is potentially toxic for the cell but also has an important ... |
Tesis Doctoral
Estudio de la cascada de señalización TOR en Chlamydonas reinhardtii
(2009)
Nos propusimos utilizar el alga verde unicelular Chlamydomonas reinhardtii como modelo para el estudio de la cascada de ... |
Artículo
The glutathione/glutaredoxin system is essential for arsenate reduction in Synechocystis sp. strain PCC 6803
(American Society for Microbiology, 2009)
Arsenic resistance in Synechocystis sp. strain PCC 6803 is mediated by an operon of three genes in which arsC codes for ... |
Artículo
Characterization of an alcohol dehydrogenase from the cyanobacterium Synechocystis sp. strain PCC 6803 that responds to environmental stress conditions via the Hik34-Rre1 two-component system
(American Society for Microbiology, 2009)
The slr1192 (adhA) gene from Synechocystis sp. strain PCC 6803 encodes a member of the medium-chain alcohol dehydrogenase/reductase ... |
Artículo
A comprehensive analysis of the peroxiredoxin reduction system in the Cyanobacterium Synechocystis sp. strain PCC 6803 reveals that all five peroxiredoxins are thioredoxin dependent
(2009)
Cyanobacteria perform oxygenic photosynthesis, which gives rise to the continuous production of reactive oxygen species, ... |
| Tesis Doctoral |
| Tesis Doctoral |
Patente. Invención
Procedimiento para el cultivo de Dunaliella salina rica en β-caroteno en fotobiorreactor tubular cerrado a la intemperie
(Oficina Española de Patentes y Marcas (OEPM), 2005)
Procedimiento para el cultivo de Dunaliella salina rica en β-caroteno en fotobiorreactor tubular cerrado a la intemperie. ... |
| Tesis Doctoral |
Artículo
Arsenic sensing and resistance system in the cyanobacterium Synechocystis sp. Strain PCC 6803
(American Society for Microbiology, 2003)
Arsenic is one of the most important global environmental pollutants. Here we show that the cyanobacterium Synechocystis ... |
Artículo
The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803
(International Union of Crystallography, 2003)
The PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803 have been crystallized ... |
Artículo
Thioredoxin-linked processes in cyanobacteria are as numerous as in chloroplasts, but targets are different
(National Academy of Sciences, 2003)
Light-dependent regulation of a growing number of chloroplast enzymatic activities has been found to occur through the ... |
Artículo
Structural studies on the synchronization of catalytic centers in glutamate synthase
(American Society for Biochemistry and Molecular Biology, 2002)
The complex iron-sulfur flavoprotein glutamate synthase (GltS) plays a prominent role in ammonia assimilation in bacteria, ... |
Tesis Doctoral
Estudio del Gen de la ferredoxina-glutamato sintasa (glsf) de anabaena sp. Pcc 7120 y de los genes del sistema de las tiorredoxinas de synechocystis sp. Pcc 6803
(2001)
El contenido de esta Tesis Doctoral comprende en una primera parte, el estudio de la enzima ferredoxina-glutamato sintasa ... |
Artículo
A gene cluster involved in metal homeostasis in the cyanobacterium Synechocystis sp. strain PCC 6803
(American Society for Microbiology, 2000)
A gene cluster composed of nine open reading frames (ORFs) involved in Ni2+, Co2+, and Zn2+ sensing and tolerance in the ... |
Artículo
Light-dependent regulation of cyanobacterial phytochrome expression
(American Society for Microbiology, 2000)
A histidine kinase protein (Cph1) with sequence homology and spectral characteristics very similar to those of the plant ... |
| Tesis Doctoral |
Tesis Doctoral
Caracterización de un mutante de girasol (Helianthus annus L.) con alto contenido de ácido esteárico en su aceite
(1999)
El trabajo ha consistido en la caracterización de un mutante de girasol con un mayor contenido de ácido esteárico que el ... |
Artículo
Glutamine synthetase inactivation by protein-protein interaction
(National Academy of Sciences, 1999)
Glutamine synthetase (GS; EC 6.3.1.2) is the pivotal enzyme of nitrogen metabolism in prokaryotes. Control of bacterial ... |
| Ponencia |
Artículo
The presence of glutamate dehydrogenase is a selective advantage for the cyanobacterium Synechocystis sp. strain PCC 6803 under nonexponential growth conditions
(American Society for Microbiology, 1999)
he unicellular cyanobacterium Synechocystis sp. strain PCC 6803 has two putative pathways for ammonium assimilation: the ... |
Artículo
Transcription of glutamine synthetase genes (glnA and glnN) from the cyanobacterium Synechocystis sp. strain PCC 6803 is differently regulated in response to nitrogen availability
(American Society for Microbiology, 1997)
In the cyanobacterium Synechocystis sp. strain PCC 6803 we have previously reported the presence of two different proteins ... |
Tesis Doctoral
Estudio de las glutamato sintasas de la cianobacteria Synechocystis sp. PCC 6803
(1996)
El objetivo de este trabajo fue, en principio, la caracterización del gen de la Fd-GOGAT de Synechocystis 6803, así como ... |
Artículo
The NADP+-isocitrate dehydrogenase gene (icd) is nitrogen regulated in cyanobacteria
(American Society for Microbiology, 1996)
NADP+-isocitrate dehydrogenase (NADP+-IDH) activity and protein levels in crude extracts from the unicellular cyanobacterium ... |
Artículo
NADP(+)-isocitrate dehydrogenase from the cyanobacterium Anabaena sp. strain PCC 7120: purification and characterization of the enzyme and cloning, sequencing, and disruption of the icd gene
(American Society for Microbiology, 1994)
NADP(+)-isocitrate dehydrogenase (NADP(+)-IDH) from the dinitrogen-fixing filamentous cyanobacterium Anabaena sp. strain ... |
Artículo
A new type of glutamine synthetase in cyanobacteria: The protein encoded by the glnN gene supports nitrogen assimilation in Synechocystis sp. strain PCC 6803
(American Society for Microbiology, 1994)
A new glutamine synthetase gene, glnN, which encodes a polypeptide of 724 amino acid residues (M(r), 79,416), has been ... |
Artículo
A mutant lacking the glutamine synthetase gene (glnA) is impaired in the regulation of the nitrate assimilation system in the cyanobacterium Synechocystis sp. strain PCC 6803
(American Society for Microbiology, 1994)
The existence in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 of two genes (glnA and glnN) coding for ... |
Tesis Doctoral
Isocitrato deshidrogenasa de cianobacterias: Purificación, caracterización y clonación del Gen icd
(1993)
El presente trabajo se ha centrado en el estudio de la isocitrato deshidrogenasa de cianobacterias, con objeto de contribuir ... |
Artículo
Effect of Glucose Utilization on Nitrite Excretion by the Unicellular Cyanobacterium Synechocystis sp. Strain PCC 6803
(American Society for Microbiology, 1993)
Up to 1 mM nitrite was excreted by Synechocystis strain 6803 cells growing under mixotrophic or photoheterotrophic conditions. ... |
Artículo
Regulation of glutamine synthetase activity in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 by the nitrogen source: Effect of ammonium
(American Society for Microbiology, 1991)
Glutamine synthetase activity from Synechocystis sp. strain PCC 6803 is regulated as a function of the nitrogen source ... |
Tesis Doctoral
Glutamina sintetasa de la cianobacteria unicelular synechocystis sp. PCC 6803: Purificación, estudios de su regulación por la fuente de nitrógeno y clonación del gen glnA
(1990)
Las cianobacterias, organismos procariotas fotosintéticos, asimilan el amonio principalmente por la acción secuencial de ... |
Artículo
Purification and Properties of Glutamine Synthetases from the Cyanobacteria Synechocystis sp. Strain PCC 6803 and Calothrix sp. Strain PCC 7601
(American Society for Microbiology, 1990)
Glutamine synthetases (GSs) from two cyanobacteria, one unicellular (Synechocystis sp. strain PCC 6803) and the other ... |
Tesis Doctoral
Regulación de la asimilación de nitrato en Chlamydomonas reinhardii. Purificación y papel fisiológico de dos isoenzimas con actividad glutamina sintetasa
(1982)
Se ha estudiado la regulación de la asimilación de nitrato en Chlamydomonas reinhardii especialmente el efecto del amonio, así como a la caracterización del proceso de entrada del nitrógeno inorgánico en dichas algas. |