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Artículo
Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells
(Elsevier, 2012)
Sphingolipids are not only important components of membranes but also have functions in protein trafficking and intracellular signaling. The LCB1 gene encodes a subunit of the serine palmitoyltransferase, which is responsible ...
Artículo
The yeast p24 complex regulates gpi-anchored protein Transport and quality control by monitoring anchor remodeling
(American Society for Cell Biology, 2011)
Glycosylphosphatidylinositol (GPI)-anchored proteins are secretory proteins that are attached to the cell surface of eukaryotic cells by a glycolipid moiety. Once GPI anchoring has occurred in the lumen of the endoplasmic ...