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Mostrando ítems 1-10 de 17
Artículo
Epithelial organisation revealed by a network of cellular contacts
(Nature Publishing Group, 2011)
The emergence of differences in the arrangement of cells is the first step towards the establishment of many organs. Understanding this process is limited by the lack of systematic characterization of epithelial organisation. ...
Artículo
Neuromuscular disease classification system
(Spie-soc photo-optical instrumentation engineers, 2013)
Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist specialist. A system for objective analysis and classification of muscular dystrophies and ...
Artículo
Age-mediated transcriptomic changes in adult mouse substantia nigra
(2013)
Substantia nigra pars compacta (SNpc) is highly sensitive to normal aging and selectively degenerates in Parkinson’s disease (PD). Until now, molecular mechanisms behind SNpc aging have not been fully investigated using ...
Artículo
X-ray emission from a liquid curtain jet when irradiated by femtosecond laser pulses
(Springer Nature, 2017)
Laser-based sources of ionizing radiation have attracted considerable attention in the last years for their broad potential applications. However, the stability and robustness of such sources are still issues that need to ...
Artículo
Live imaging of Drosophila imaginal disc development
(National Academy of Sciences, 2010)
Live imaging has revolutionized the analysis of developmental biology over the last few years. The ability to track in real time the dynamic processes that occur at tissue and cellular levels gives a much clearer view of ...
Artículo
Nintedanib decreases muscle fibrosis and improves muscle function in a murine model of dystrophinopathy
(Nature Publishing Group, 2018)
Duchenne muscle dystrophy (DMD) is a genetic disorder characterized by progressive skeletal muscle weakness. Dystrophin deficiency induces instability of the sarcolemma during muscle contraction that leads to muscle necrosis ...
Artículo
Author Correction: Scutoids are a geometrical solution to three-dimensional packing of epithelia
(Nature Research, 2018)
Artículo
ATM specifically mediates repair of double-strand breaks with blocked DNA ends
(Nature Publishing Group, 2014)
Ataxia telangiectasia is caused by mutations in ATM and represents a paradigm for cancer predisposition and neurodegenerative syndromes linked to deficiencies in the DNA-damage response. The role of ATM as a key regulator ...
Artículo
Topological Progression in Proliferating Epithelia Is Driven by a Unique Variation in Polygon Distribution
(Public Library of Science, 2013)
Morphogenesis is consequence of lots of small coordinated variations that occur during development. In proliferating stages, tissue growth is coupled to changes in shape and organization. A number of studies have analyzed ...