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Mostrando ítems 1-5 de 5
Artículo
The Cockayne syndrome protein B is involved in the repair of 5-AZA-2′-deoxycytidine-induced DNA lesions
(Impact Journals, 2018)
The Cockayne Syndrome Protein B (CSB) plays an essential role in Transcription-Coupled Nucleotide Excision Repair (TC-NER) by recruiting repair proteins once transcription is blocked with a DNA lesion. In fact, CSB-deficient ...
Artículo
Zebularine induces replication-dependent double-strand breaks which are preferentially repaired by homologous recombination
(Elsevier, 2017)
Zebularine is a second-generation, highly stable hydrophilic inhibitor of DNA methylation with oral bioavailability that preferentially target cancer cells. It acts primarily as a trap for DNA methyl transferases (DNMTs) ...
Artículo
Realización de seminarios a distancia mediante el uso de herramientas de blackboard (wimbaclassroom de webct) para conocer las aplicaciones y avances de los cultivos celulares en relación al ámbito laboral
(Red Estatal de Docencia Universitaria, 2010)
La asignatura de Cultivos Celulares impartida en la Licenciatura de Biología de la Universidad de Sevilla, proporciona a los alumnos información teórica y práctica en esta materia. El gran avance tecnológico de los ...
Artículo
Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons
(Taylor & Francis LTD, 2017)
Purpose: RENEB, ‘Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,’ is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely ...
Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
(Oxford University Press, 2013)
5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological diseases and works by being incorporated into DNA and trapping DNMT. It is unclear what DNA ...