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Mostrando ítems 1-10 de 16
Artículo
Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
(Taylor & Francis Open Access, 2021)
We have designed unprecedented cholinesterase inhibitors based on 1-deoxynojirimycin as potential anti-Alzheimer’s agents. Compounds are comprised of three key structural motifs: the iminosugar, for interaction with ...
Ponencia
Strangeness on the nucleon
(AIP Publishing, 2013)
Artículo
Alkoxyamine-cyanoborane adducts: Efficient cyanoborane transfer agents
(Royal Society of Chemistry, 2011)
We report the synthesis of the hitherto unknown zwitterionic alkoxyamino cyanoboranes by reduction of O-alkyloximes with sodium cyanoborohydride; unprecedented cyanoboronated N-alkoxyformamidines were also isolated as ...
Artículo
Remarks on the controllability of some parabolic equations and systems
(Sociedad Española de Matemática Aplicada, 2006)
We present a review of recent results concerning the null controllability of parabolic systems. Among others, we will consider the heat equation, the Burgers, Navier-Stokes and Ginzburg-Landau equations, etc. We will also ...
Artículo
Some inverse and control problems for fluids
(Université Blaise Pascal de Clermont-Ferrand, 2013)
This paper deals with some inverse and control problems for the Navier-Stokes and related systems. We will focus on some particular aspects that have recently led to interesting (theoretical and numerical) results: geometric ...
Artículo
Tacrine-sugar mimetic conjugates as enhanced cholinesterase inhibitors
(Royal Society of Chemistry, 2021-03-14)
We have used the Cu(i)-catalyzed azide-alkyne Huisgen cycloaddition reaction to obtain two families of bivalent heterodimers where tacrine is connected to an azasugar or iminosugar, respectively,vialinkers of variable ...
Artículo
A posteriori error analysis for two non-overlapping domain decomposition techniques
(Elsevier, 2009-06)
This paper is devoted to the construction of fast solvers for penalty domain decomposition techniques, based upon a posteriori error analysis. We introduce a penalty non-overlapping domain decomposition method (ddm) motivated ...
Ponencia
Analysis of Charged-Current Neutrino-Nucleus Cross Section
(AIP Publishing, 2013)
A study of the cross section for chaged-current quasielastic (CCQE) scattering on nuclei has been performed using a description of nuclear dynamics based on the Relativistic Fermi Gas model (RFG). The role played by different ...
Artículo
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents
(Elsevier, 2017)
We have designed a series of tacrine-based homo- and heterodimers that incorporate an antioxidant tether (selenoureido, chalcogenide) as new dual compounds: for the treatment of Alzheimer's disease and as antiproliferative ...
Artículo
Asymptotic behavior of an elastic beam fixed on a small part of one of its extremities
(Elsevier, 2004-06-15)
We study the asymptotic behavior of the solution of an anisotropic, heterogeneous, linearized elasticity problem in a cylinder whose diameter ε tends to zero. The cylinder is assumed to be fixed (homogeneous Dirichlet ...