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Tesis Doctoral
Estudio de la arquitectura epitelial en 3D, su variación natural y la aparición de patrones morfológicos a nivel celular
(2023-07-11)
Una de las cuestiones más fascinantes de la Biología del desarrollo es entender cómo los tejidos y órganos adquieren su forma, crítica para su función, en un proceso que se denomina morfogénesis. La fiel ejecución del ...
Tesis Doctoral
Scutoids unveil the three-dimensional packing in curved epithelia
(2020-07-16)
As animals develop, the initial simple planar epithelia of the early embryos must acquire complex three-dimensional architectures to form the final functional tissues of the organism. Epithelial bending is, therefore, a ...
Tesis Doctoral
Topological analysis of the tumour microenvironment to study Neuroblastoma
(2020-09-03)
Solid tumours and their tumour microenvironment (TME) can be considered as complex networks whose elements are in constant physical stress. All the elements of the TME, including tumour cells, stromal cells, immune and ...
Tesis Doctoral
Mechanisms of epithelial packing in proliferative tissues
(2024-05-02)
Tissue morphogenesis is intimately linked with the complex changes that occur in the shape and organization of individual cells. In curved epithelia, cells possess the capacity to intercalate along their own apico-basal ...
Tesis Doctoral