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Mostrando ítems 1-7 de 7
Artículo
Time-Dependent Collagen Fibered Structure in the Early Distraction Callus: Imaging Characterization and Mathematical Modeling
(Biomedical Engineering Society, 2022-12)
Collagen is a ubiquitous protein present in regenerating bone tissues that experiences multiple biological phenomena during distraction osteogenesis until the deposition of phosphate crystals. This work combines fluorescence ...
Artículo
Traction force reconstruction assessment on real three-dimensional matrices and cellular morphologies
(Elsevier, 2023-05-01)
Traction force microscopy (TFM) allows to estimate tractions on the surface of cells when they mechanically interact with hydrogel substrates that mimic the extracellular matrix (ECM). The field of mechanobiology has a ...
Artículo
An in silico study on the influence of extracellular matrix mechanics on vasculogenesis
(Elsevier, 2023-04)
Background and objectives: Blood vessels form a network of capillaries throughout the body that perform essential functions for life. Vasculogenesis, i.e. the formation of new blood vessels, is regulated by many factors, ...
Artículo
A new reliability-based data-driven approach for noisy experimental data with physical constraints
(Elsevier, 2018-01)
Data Science has burst into simulation-based engineering sciences with an impressive impulse. However, data are never uncertainty-free and a suitable approach is needed to face data measurement errors and their intrinsic ...
Artículo
A mechanobiological model for tumor spheroid evolution with application to glioblastoma: A continuum multiphysics approach
(Elsevier, 2023)
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel matrix, that are used, among other applications, as a technological platform to investigate ...
Artículo
An unsupervised data completion method for physically-based data-driven models
(Elsevier, 2019-02)
Data-driven methods are an innovative model-free approach for engineering and sciences, still in process of maturation. The idea behind is the combination of data analytics techniques, to handle the huge amount of data ...
Artículo
A mechanobiological model for tumor spheroid evolution with application to glioblastoma: a continuum multiphysics approach
(Elsevier, 2023-06)
Background: Spheroids are in vitro quasi-spherical structures of cell aggregates, eventually cultured within a hydrogel matrix, that are used, among other applications, as a technological platform to investigate tumor ...