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Artículo
Metabolites and tissue distribution of resveratrol in the pig
(Wiley-Blackwell, 2011-08)
Scope: trans-Resveratrol (RES) and/(or) its metabolites exert many effects in vivo. Our aim was to study the metabolism and tissue distribution of RES using the pig, a mammal physiologically close to humans. Methods and ...
Artículo
Highly Polar Carbohydrates Stack Onto DNA Duplexes Via CH/π Interactions
(American Chemical Society, 2011)
Carbohydrate-nucleic acid contacts are known to be a fundamental part of some drug-DNA recognition processes. Most of these interactions occur through the minor groove of DNA, such as in the calicheamicin or anthracycline ...