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Artículo
Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
(Springer Nature, 2011)
Oligoribonucleotide conjugates and the corresponding siRNA duplexes against tumor necrosis factor carrying one, two, or four glucose and galactose residues at the 5'-end have been prepared using phosphoramidite chemistry. ...
Artículo
Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
(Elsevier, 2013)
Oligoribonucleotide conjugates carrying apolar carbohydrates at the 5′-end and the corresponding siRNA duplexes have been prepared using phosphoramidite chemistry. All the carbohydrate-siRNA derivatives were compatible ...