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Artículo
Synthesis, cell-surface binding, and cellular uptake of fluorescently labeled glucose-DNA conjugates with different carbohydrate presentation
(American Chemical Society, 2010)
Oligonucleotide conjugates carrying carbohydrates at the 5′-end have been prepared. Glucose, fucose, and saccharides containing glucose at the nonreducing end were attached to DNA strands using the classical phosphoramidite ...
Artículo
Highly Polar Carbohydrates Stack Onto DNA Duplexes Via CH/π Interactions
(American Chemical Society, 2011)
Carbohydrate-nucleic acid contacts are known to be a fundamental part of some drug-DNA recognition processes. Most of these interactions occur through the minor groove of DNA, such as in the calicheamicin or anthracycline ...
Artículo
Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
(Springer Nature, 2011)
Oligoribonucleotide conjugates and the corresponding siRNA duplexes against tumor necrosis factor carrying one, two, or four glucose and galactose residues at the 5'-end have been prepared using phosphoramidite chemistry. ...