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Artículo
Porous titanium substrates coated with a bilayer of bioactive glasses
(Elsevier, 2020-09)
Porous titanium substrates coated by dripping-sedimentation technique with a novel bilayer of (45S5 / 1393) bioactive glasses are proposed to overcome some limitations of the use of titanium for implants, such as the stress ...
Artículo
Synthesis and deposition of silver nanoparticles on porous titanium substrates for biomedical applications
(Elsevier, 2021-01)
Ti implants are highly biocompatible and allow orderly bone growth but, unfortunately, in the first five years after implantation, 5–10% of them fail due to poor osseointegration and to the presence of bacterial infections ...
Artículo
GPR120/FFAR4 Pharmacology: Focus on Agonists in Type 2 Diabetes Mellitus Drug Discovery
(American Chemical Society, 2021)
The G-protein coupled receptors (GPCRs) activated by free fatty acids (FFAs) have emerged as new and exciting drug targets, due to their plausible translation from pharmacology to medicines. This perspective aims to report ...
Artículo
Ink-jet 3D printing as a strategy for developing bespoke non-eluting biofilm resistant medical devices
(Elsevier, 2022)
Chronic infection as a result of bacterial biofilm formation on implanted medical devices is a major global healthcare problem requiring new biocompatible, biofilm-resistant materials. Here we demonstrate how bespoke devices ...
Artículo
Influence of Femtosecond Laser Modification on Biomechanical and Biofunctional Behavior of Porous Titanium Substrates
(MDPI, 2022-04)
Bone resorption and inadequate osseointegration are considered the main problems of titanium implants. In this investigation, the texture and surface roughness of porous titanium samples obtained by the space holder technique ...
Tesis Doctoral
Diseño y síntesis de nuevos agentes quimioterápicos: receptores acoplados a proteína G (NK1 y CB2) y factores de transcripción (Nrf2 y STAT3) como dianas terapéuticas
(2022-12-02)
El cáncer es una enfermedad de gran impacto sanitario, económico y social en la población, para la que aún no se dispone de un tratamiento eficaz. Por ello, en la presente tesis doctoral nos hemos propuesto el desarrollo ...
Artículo
Bi-Magnetic Core-Shell CoFe2O4@MnFe2O4 Nanoparticles for In Vivo Theranostics
(MDPI, 2020)
In this work, we report the synthesis and characterization of three magnetic nanosystems, CoFe2O4, CoFe2O4@ZnFe2O4, and CoFe2O4@MnFe2O4, which were developed as potential theranostic agents for magnetic hyperthermia and ...
Artículo
Homochiral imidazolium-based dicarboxylate silver(i) compounds: synthesis, characterisation and antimicrobial properties
(Royal Society of Chemistry, 2022-03)
Complexes [Ag(LR)], 2 (LR = 2,2′-(imidazolium-1,3-diyl)di(2-alkylacetate)), were prepared by treatment of compounds HLR, 1, with Ag2O. They were characterised by analytical, spectroscopic (IR, 1H and 13C NMR and polarimetry) ...
Artículo
The effect of age on binocular vision normative values
(Slack, Inc., 2020)
Purpose: To establish a relationship between age and horizontal heterophoria, horizontal fusional vergence amplitudes, and vergence facility testing. Methods: The sample consisted of 112 patients with a mean age of 39.8 ± ...
Artículo
Scaling Up Magnetic Nanobead Synthesis with Improved Stability for Biomedical Applications
(American Chemical Society, 2022)
The growing interest in multifunctional nano-objects based on polymers and magnetic nanoparticles for biomedical applications motivated us to develop a scale-up protocol to increase the yield of polymeric magnetic nanobeads ...