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Mostrando ítems 1-10 de 11
Artículo
Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice
(Oxford University Press, 2020)
In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of psychosis in the hope that these could aid the prediction of onset and clinical outcome. Despite ...
Artículo
Using machine learning and structural neuroimaging to detect first episode psychosis: Reconsidering the evidence
(Oxford University Press, 2020)
Despite the high level of interest in the use of machine learning (ML) and neuroimaging to detect psychosis at the individual level, the reliability of the findings is unclear due to potential methodological issues that ...
Artículo
Association Between Specific Childhood Adversities and Symptom Dimensions in People With Psychosis: Systematic Review and Meta-Analysis
(Oxford University Press, 2021)
Despite the accepted link between childhood abuse and positive psychotic symptoms, findings between other ad versities, such as neglect, and the remaining dimensions in people with psychosis have been inconsistent, ...
Artículo
Aripiprazole as a candidate treatment of COVID-19 identified through genomic analysis
(Frontiers Media SA, 2021)
Background: Antipsychotics modulate expression of inflammatory cytokines and inducible inflammatory enzymes. Elopiprazole (a phenylpiperazine antipsychotic drug in phase 1) has been characterized as a therapeutic drug to ...
Artículo
Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study
(MDPI, 2020)
Toll-like receptors (TLRs) are a pivotal component of the innate immune system that seem to have a role in the pathogenesis of psychosis. The purpose of this work was to compare the expression and functionality of 9 TLRs ...
Artículo
Childhood trauma and substance use underlying psychosis: a systematic review
(Taylor and Francis Group, 2020)
Background: Schizophrenia spectrum disorders (SSD) are mental diseases caused by a combination of genetic susceptibility and a number of environmental factors. Among these factors, the role of traumatic events suffered in ...
Artículo
Understanding sex differences in long-term outcomes after a first episode of psychosis
(Springer Nature, 2020)
While sex differences in schizophrenia have long been reported and discussed, long-term sex differences in outcomes among first episode of psychosis (FEP) patients in terms of the efficacy of Early Intervention Services ...
Artículo
Routine cerebrospinal fluid parameters as biomarkers in first-episode psychosis: A prospective observational study
(PERGAMON-ELSEVIER SCIENCE LTD, 2022)
In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate early diagnosis, disease stratification, therapeutic choice and outcome prediction. Few studies ...
Artículo
Routine cerebrospinal fluid parameters as biomarkers in first-episode psychosis: A prospective observational study
(Pergamon Elsevier Science LTD, 2021)
In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate early diagnosis, disease stratification, therapeutic choice and outcome prediction. Few studies have ...
Artículo
Data regarding active psychosis and functional outcome, among other clinical variables, during early phases of the illness in first-episode psychosis in the PAFIP 10-year follow-up program
(Elsevier, 2020)
This article describes data related to the research study entitled "Duration of active psychosis during early phases of the illness and functional outcome: The PAFIP 10-year follow-up study." [1]. We present data concerning ...