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Mostrando ítems 11-18 de 18
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Genetic copy number variants, cognition and psychosis: a meta analysis and a family study
(Springer Nature, 2021)
The burden of large and rare copy number genetic variants (CNVs) as well as certain specific CNVs increase the risk of developing schizophrenia. Several cognitive measures are purported schizophrenia endophenotypes and ...
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Routine cerebrospinal fluid parameters as biomarkers in first-episode psychosis: A prospective observational study
(Pergamon Elsevier Science LTD, 2021)
In recent years, multiple studies have investigated the role of biomarkers in first-episode psychosis (FEP) to facilitate early diagnosis, disease stratification, therapeutic choice and outcome prediction. Few studies have ...
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1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
(Springer Nature, 2021)
Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...
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Lifestyle in undergraduate students and demographically matched controls during the COVID-19 pandemic in Spain
(MDPI, 2021)
Few studies have used a multidimensional approach to describe lifestyle changes among undergraduate students during the COVID-19 pandemic or have included controls. This study aimed to evaluate lifestyle behaviors and ...
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In- and outpatient lifestyle interventions on diet and exercise and their effect on physical and psychological health: a systematic review and meta-analysis of randomised controlled trials in patients with schizophrenia spectrum disorders and first episode of psychosis
(2021)
atients with non-affective psychosis often lead unhealthy lifestyles. We performed a systematic review and meta-analysis on non-pharmacological RCTs for improvement of diet and physical activity in non-affective psychosis ...
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Short-term emotional impact of COVID-19 pandemic on Spaniard health workers
(Elsevier Science BV, 2021-01-01)
Background: The aims of this study were to evaluate the short-term impact of 2019-nCoV outbreak on the mental/ psychological state of Spaniard health care workers (HCWs) and to explore the influencing factors, including ...
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A polygenic resilience score moderates the genetic risk for schizophrenia
(Springer Nature, 2021)
Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531–538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited ...
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Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group
(Springer Nature, 2021)
DNA methylation, which is modulated by both genetic factors and environmental exposures, may offer a unique opportunity to discover novel biomarkers of disease-related brain phenotypes, even when measured in other tissues ...