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Artículo
Whole transcription profile of responders to anti-tnf drugs in pediatric inflammatory bowel disease
(MDPI, 2021-01-08)
Background: Up to 30% of patients with pediatric inflammatory bowel disease (IBD) do not respond to anti-Tumor Necrosis Factor (anti-TNF) therapy. The aim of this study was to identify pharmacogenomic markers that predict ...
Artículo
Gene signatures of early response to anti-TNF drugs in pediatric inflammatory bowel disease
(MDPI, 2020)
Around a 20–30% of inflammatory bowel disease (IBD) patients are diagnosed before they are 18 years old. Anti-TNF drugs can induce and maintain remission in IBD, however, up to 30% of patients do not respond. The aim of ...