Buscar
Mostrando ítems 1-3 de 3
Artículo
NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice
(Willey, 2019-09-23)
While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive ...
Artículo
Autophagic dysfunction in patients with Papillon-Lefèvre syndrome is restored by recombinant cathepsin C treatment
(2018)
Background: Cathepsin C (CatC) is a lysosomal enzyme involved in activation of serine proteases from immune and inflammatory cells. Several loss-of-function mutations in the CatC gene have been shown to be the genetic ...
Artículo
Molecular inflammation and oxidative stress are shared mechanisms involved in both myocardial infarction and periodontitis
(Blackwell Munksgaard, 2020)
Background and Objective. Our aims were to improve the understanding of the pathogenic relationship between cardiovascular diseases and periodontitis and to generate new perspectives in the prevention and treatment of acute ...