Citología e Histología Normal y Patológica: Envíos recientes
Mostrando ítems 21-40 de 304
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Patente. Invención
Utilización de nanopartículas de metales nobles como inmunomoduladores y composición inmunomoduladora
(Oficina Española de Patentes y Marcas (OEPM), 2011-02-28)Utilización de nanopartículas de metales nobles como inmunomoduladores y composición inmunomoduladora. La presente invención ...
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Artículo
Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization
(Rockefeller University Press, 2021)Rac1 GTPase is hyperactivated in tumors and contributes to malignancy. Rac1 disruption of junctions requires its effector ...
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Artículo
From precision medicine to imprecision medicine through limited diagnostic ability to detect low allelic frequency mutations
(2020)Routine molecular testing in NSCLC is currently moving beyond the classical EGFR mutational analysis and the evolving ...
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Artículo
Estudio de biocompatibilidad y osteointegración de nuevos materiales protésicos
(Ibáñez & Plaza, 2020)Objetivos Los implantes óseos son utilizados cada vez con mayor frecuencia en la práctica clínica y, entre los materiales, ...
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Artículo
Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma
(Wiley, 2020)In prostate adenocarcinoma (PCa), distinction between indolent and aggressive disease is challenging. Around 50% of PCa ...
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High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma
(MDPI, 2020)Ewing sarcoma (EwS) is an aggressive cancer displaying an undifferentiated small-round-cell histomorphology that can be ...
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Artículo
Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Systemic lupus erythematosus (SLE) is a chronic immune-inflammatory disease characterized by multiorgan affectation and ...
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Artículo
Spanish National Registry of Major Osteoporotic Fractures (REFRA) seen at Fracture Liaison Services (FLS): objectives and quality standards
(SPRINGER, 2022)Summary REFRA-FLS is a new registry in Spain aimed at identifying individuals over 50 years of age with a fragility ...
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Artículo
Histopathological Features of Pendred Syndrome Thyroids Align with Differences in the Expression of Thyroid‑Specific Markers, Apical Iodide Transporters, and Ciliogenesis Process
(HUMANA PRESS INC, 2022)Pendred syndrome (PDS) is an autosomal recessive disorder caused by mutations in the gene that encodes pendrin. Pendred ...
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Circulating Osteogenic Progenitor Cells Enhanced with Teriparatide or Denosumab Treatment
(MDPI, 2022)Circulating osteogenic precursor (COP) cells are peripheral blood cells with a capacity for osteogenesis. The objective ...
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An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogénesis
(Public Library of Science, 2020)The presence of the chimeric EWSR1-FLI1 oncoprotein is the main and initiating event defining Ewing sarcoma (ES). The ...
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Osteoblastic cell behavior and gene expression related to bone metabolism on different titanium surfaces
(MDPI, 2023-02-09)The surface topography of titanium dental implants has a great influence on osseointegration. In this work, we try to ...
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Artículo
Cell consequences of loss of function of the epigenetic factor EHMT1
(Elsevier, 2023)EHMT1 is an epigenetic factor with histone methyltransferase activity that appears mutated in Kleefstra syndrome, a ...
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Artículo
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
(Nature Publishing Group, 2020)Ewing sarcoma (EwS) is an aggressive childhood cancer likely originating from mesenchymal stem cells or osteo-chondrogenic ...
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Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma
(Wiley, 2020)YAP1 and TAZ (WWTR1) oncoproteins are thefinal transducers of the Hippo tumor suppressor pathway. Deregula-tion of the ...
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A Quantitative Digital Analysis of Tissue Immune Components Reveals an Immunosuppressive and Anergic Immune Response with Relevant Prognostic Significance in Glioblastoma
(MDPI, 2022)Objectives: Immunostimulatory therapies using immune checkpoint blockers show clinical activity in a subset of glioblastoma ...
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Artículo
Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial
(BMJ Journals, 2020)Background: Sarcomas exhibit low expression of factors related to immune response, which could explain the modest activity ...
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Artículo
Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors
(MDPI, 2020)The embryonal renal cancer Wilms tumor (WT) accounts for 7% of all children’s malignancies. Its most frequent molecular ...
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Artículo
An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma
(Nature Research, 2022-09-17)The advent of dose intensified interval compressed therapy has improved event-free survival for patients with localized ...
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Evidence for Oxidative Pathways in the Pathogenesis of PD Are Antioxidants Candidate Drugs to Ameliorate Disease Progression
(MDPI, 2022-06-22)Parkinson’s disease (PD) is a progressive neurodegenerative disorder that arises due to a complex and variable interplay ...