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Tesis Doctoral
Cálculo de un índice de riesgo de padecer diabetes gestacional para su uso como cribado universal.
(2018-07-18)
Título:Cálculo de un índice de riesgo de padecer diabetes gestacional para su uso como cribado universal. Introducción: El diagnóstico de la diabetes mellitus gestacional sigue careciendo de una estrategia consensuda y ...
Artículo
Role of Sam68 in post-transcriptional gene regulation
(MDPI AG, 2013-11-28)
The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology ...
Artículo
Artículo
Human amniotic membrane conditioned medium inhibits proliferation and modulates related microRNAs expression in hepatocarcinoma cell
(2019-10-02)
The placental stem cells have called the focus of attention for their therapeutic potential to treat diferent diseases, including cancer. There is plenty evidence about the antiproliferative, antiangiogenic and ...
Artículo
Leptin action in normal and pathological pregnancies
(2018)
Leptin is now considered an important signalling molecule of the reproductive system, as it regulates the production of gonadotrophins, the blastocyst formation and implantation, the normal placentation, as well as the ...
Artículo
Circulating regulatory T cells from breast cancer patients in response to neoadjuvant chemotherapy
(Amer Publ Co, 2019)
Background: Immune escape of tumor cells is a new hallmark of cancer in general, and breast cancer, in particular. Previous studies have demonstrated that the immunological profile in peripheral blood may be a prognostic ...
Artículo
Obesity and Breast Cancer: Role of Leptin
(2019-07-18)
Obesity-related breast cancer is an important threat that affects especially post-menopausal women. The link between obesity and breast cancer seems to be relying on the microenvironment generated at adipose tissue level, ...
Artículo
Sam68 Mediates the Activation of Insulin and Leptin Signalling in Breast Cancer Cells
(Public Library Science, 2016)
Obesity is a well-known risk factor for breast cancer development in postmenopausal women. High insulin and leptin levels seem to have a role modulating the growth of these tumours. Sam68 is an RNA-binding protein with ...
Tesis Doctoral
Prevalencia del déficit de vitamina D y significado pronóstico en pacientes ancianos ingresados por síndrome coronario agudo.
(2018-06-19)
Introducción: La deficiencia de vitamina D (25-OH-VITD) se ha relacionado con la génesis de la ateroesclerosis coronaria así cómo con el desarrollo de eventos cardiovasculares. Sin embargo, los estudios que reflejan esta ...
Tesis Doctoral
Epigenética de los procesos de autorrenovación, pluripotencialidad y diferenciación de las células troncales
(2010)
El objetivo general de esta tesis ha sido definir la importancia que poseen los procesos epigenéticos sobre el mantenimiento del estado pluripotente y el proceso de diferenciación de las células troncales embrionarias. ...