Buscar
Mostrando ítems 1-10 de 10
Artículo
Sodium Lauryl Sulfate-Conjugated Cationic Gemini-Surfactant-Capped Gold Nanoparticles as Model System for Biomolecule Recognition
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Surfactant-based nanostructures are promising materials for designing novel colorimetric biosensors based on aggregation/disaggregation phenomena. In this work, a colorimetric sensor based on the plasmonic shift of ...
Artículo
Gold Nanosystems Covered with Doxorubicin/DNA Complexes: A Therapeutic Target for Prostate and Liver Cancer
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Different gold nanosystems covered with DNA and doxorubicin (Doxo) were designed and synthesized for cancer therapy, starting from Au@16-Ph-16 cationic nanoparticles and DNA–Doxo complexes prepared under saturation conditions. ...
Artículo
Synergistic Antibacterial Effects of Amoxicillin and Gold Nanoparticles: A Therapeutic Option to Combat Antibiotic Resistance
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)
Compacted Au@16-mph-16/DNA-AMOX (NSi) nanosystems were prepared from amoxicillin (AMOX) and precursor Au@16-mph-16 gold nanoparticles (Ni) using a Deoxyribonucleic acid (DNA) biopolymer as a glue. The synthesized nanocarrier ...
Artículo
Colorimetric, naked-eye detection of lysozyme in human urine with gold nanoparticles
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The stabilizing effect of lysozymes to salt addition over a gold colloid are exploited in order to detect lysozymes in human urine samples. The present research is aimed at the development of a fast, naked-eye detection ...
Artículo
Biocompatible DNA/5-fluorouracil-gemini surfactant-functionalized gold nanoparticles as promising vectors in lung cancer therapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The design and preparation of novel nanocarriers to transport cancer drugs for chemotherapy purposes is an important line of research in the medical field. A new 5-fluorouracil (5-Fu) transporter was designed based on the ...
Artículo
Lysozyme–aunps interactions: Determination of binding free energy
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
Investigation and optimization of lysozyme (Lys) adsorption onto gold nanoparticles, AuNPs, were carried out. The purpose of this study is to determine the magnitude of the AuNPs– lysozyme interaction in aqueous media by ...
Artículo
Understanding gold nanoparticles interactions with chitosan: Crosslinking agents as novel strategy for direct covalent immobilization of biomolecules on metallic surfaces
(Elsevier, 2020-03-15)
The development of a new method for covalent immobilization of biomolecules on the surface of bare gold nanoparticles (AuNPs) by using crosslinking agents in one step is presented. A very compatible biopolymer such ...
Artículo
AuNPs-DNA non-covalent interactions: improve of some studies and new avenues of research from negative results
(Universidade Federal do Espírito Santo, 2013)
Due to their chemical stability, high biocompatibility, excellent structural, optical, magnetic and catalytic properties, gold nanoparticles (AuNPs) have been widely used as therapeutics, delivery agents and transfection ...
Artículo
Use of Nanoparticles to Prevent Resistance to Antibiotics—Synthesis and Characterization of Gold Nanosystems Based on Tetracycline
(Multidisciplinary Digital Publishing Institute (MDPI), 2022)
Antimicrobial resistance (AMR) is a serious public health problem worldwide which, according to the World Health Organization (WHO), requires research into new and more effective drugs. In this work, both gold nanoparticles ...
Artículo
pH-temperature dual-sensitive nucleolipid-containing stealth liposomes anchored with PEGylated AuNPs for triggering delivery of doxorubicin
(Elsevier, 2022)
Liposomes (Lip) are useful nanocarriers for drug delivery and cancer nanomedicine because of their ability to efficiently encapsulate drugs with different physical and chemical properties. The pH gradient between normal ...