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Tesis Doctoral
Implante de progenitores neurales en un modelo de lesión del sistema oculomotor
(2015-11-11)
El implante de células progenitoras neurales en el sistema nervioso central lesionado es una poderosa herramienta reparadora. Sin embargo, aún no se han evaluado extensamente los efectos de dichos implantes sobre el patrón ...
Artículo
Nerve Growth Factor Regulates the Firing Patterns and Synaptic Composition of Motoneurons
(Society for Neuroscience, 2010)
Target-derived neurotrophins exert powerful synaptotrophic actions in the adult brain and are involved in the regulation of different forms of synaptic plasticity. Target disconnection produces a profound synaptic stripping ...
Artículo
Effects of Selective Deafferentation on the Discharge Characteristics of Medial Rectus Motoneurons
(Society for Neuroscience, 2018)
Medial rectus motoneurons receive two main pontine inputs: abducens internuclear neurons, whose axons course through the medial longitudinal fasciculus (MLF), and neurons in the lateral vestibular nucleus, whose axons ...
Artículo
Neural Progenitor Cell Implants in the Lesioned Medial Longitudinal Fascicle of Adult Cats Regulate Synaptic Composition and Firing Properties of Abducens Internuclear Neurons
(Society for Neuroscience, 2014)
Transplants of neural progenitor cells (NPCs) into the injured CNS have been proposed as a powerful tool for brain repair, but, to date, few studies on the physiological response of host neurons have been reported. Therefore, ...
Artículo
Dual encoding of muscle tension and eye position by abducens motoneurons
(Society for Neuroscience, 2011)
Extraocular muscle tension associated with spontaneous eye movements has a pulse-slide-step profile similar to that of motoneuron firing rate. Existing models only relate motoneuron firing to eye position, velocity and ...
Artículo
Complementary Actions of BDNF and Neurotrophin-3 on the Firing Patterns and Synaptic Composition of Motoneurons
(Society for Neuroscience, 2009)
Neurotrophins, as target-derived factors, are essential for neuronal survival during development, but during adulthood, their scope of actions widens to become also mediators of synaptic and morphological plasticity. Target ...
Artículo
Axons Giving Rise to the Palisade Endings of Feline Extraocular Muscles Display Motor Features
(Society for Neuroscience, 2013)
Palisade endings are nerve specializations found in the extraocular muscles (EOMs) of mammals, including primates. They have long been postulated to be proprioceptors. It was recently demonstrated that palisade endings are ...