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Artículo
Connexin43 Region 266–283, via Src Inhibition, Reduces Neural Progenitor Cell Proliferation Promoted by EGF and FGF-2 and Increases Astrocytic Differentiation
(2020)
Neural progenitor cells (NPCs) are self-renewing cells that give rise to the major cells in the nervous system and are considered to be the possible cell of origin of glioblastoma. The gap junction protein connexin43 (Cx43) ...
Artículo
Targeting Protein Kinase C in Glioblastoma Treatment
(MDPI, 2021)
Glioblastoma (GBM) is the most frequent and aggressive primary brain tumor and is associated with a poor prognosis. Despite the use of combined treatment approaches, recurrence is almost inevitable and survival longer than ...
Artículo
Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
(MDPI, 2019)
The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit. Among these, extracellular ...
Artículo
Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments
(Frontiers Media, 2021)
Glioblastoma (GBM) is the most common form of brain tumor characterized by its resistance to conventional therapies, including temozolomide, the most widely used chemotherapeutic agent in the treatment of GBM. Within the ...