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Mostrando ítems 1-7 de 7
Tesis Doctoral
Cytosolic interaction between respiratory cytochrome c and 14-3-3 protein family members facilitates programmed cell death in humans and plants
(2017-09-22)
The development, as well as the homeostatic control of multi-cellular organisms, requires programmed cell death processes. In humans and plants, such events entail an intricate protein network in which cytochrome c plays ...
Tesis Doctoral
Reconocimiento molecular y análisis estructural de complejos transitorios entre proteínas
(2005)
Las interacciones trasitorias entre biomoléculas se han convertido en el centro de la investigación de muchas áreas de la Bioquímica Moderna. La caracterización estructural continuada, utilizando cualquiera de las técnicas ...
Tesis Doctoral
Novel insights into the mechanism of electron transfer in mitochondrial cytochrome c and its regulation by post-translational modifications
(2023-06-30)
Las células que componen nuestro cuerpo obtienen la mayor parte de la energía que necesitan para vivir, de los alimentos que ingerimos y del aire que respiramos, gracias a unos orgánulos especializados, denominados ...
Tesis Doctoral
Redox biointeractome of cytochromes in respiration and photosynthesis
(2015-10-06)
Protein complex formation is at least a two-step process in which the formation of a final, well-defined complex entails the initial formation of a dynamic encounter complex. Highly transient complexes, with lifetimes in ...
Tesis Doctoral
Structural approach to the hur function
(2013-06-06)
En esta tesis se presenta un análisis estructural de la proteína de unión a ARN HuR y, en particular, se profundiza en el análisis con su estructura modular y a su regulación post-traducional mediante fosforilación. Los ...
Tesis Doctoral
Regulatory network built by Cytochrome c with Histone Chaperones in response to DNA damage
(2020-01-17)
The maintenance of genome integrity is a critical process for cell life. To face DNA lesions, living beings have developed a complex network called DNA damage response (DDR), which encompasses an intricate phosphorylation ...
Tesis Doctoral
Mechanistic insights into the post-translational regulation of RNA-binding proteins in cell life and disease
(2024-02-01)
Cell signaling networks modulate gene expression in response to internal and external stimuli. Rapid cellular adaptation to changing physiological and environmental conditions requires a strict control of the mRNA metabolism. ...