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Artículo
Mechanics and self-organization in tissue development
(Elsevier, 2021)
Self-organization is an all-important feature of living systems that provides the means to achieve specialization and functionality at distinct spatio-temporal scales. Herein, we review this concept by addressing the packing ...
Artículo
CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia
(Elsevier, 2023)
Decades of research have not yet fully explained the mechanisms of epithelial self-organization and 3D packing. Single-cell analysis of large 3D epithelial libraries is crucial for understanding the assembly and function ...
Artículo
Curvature in Biological Systems: Its Quantification, Emergence, and Implications across the Scales
(John Wiley and Sons Inc, 2023-03-29)
Surface curvature both emerges from, and influences the behavior of, living objects at length scales ranging from cell membranes to single cells to tissues and organs. The relevance of surface curvature in biology is ...