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Artículo
Trimeric G proteins modulate the dynamic interaction of PKAII with the Golgi complex
(The Company of Biologists Ltd, 1999)
The Golgi complex represents a major subcellular location of protein kinase A (PKA) concentration in mammalian cells where it has been previously shown to be involved in vesicle-mediated protein transport processes. We ...
Artículo
Protein kinase A activity is required for the budding of constitutive transport vesicles from the trans-Golgi network
(National Academy of Sciences of the USA, 1997)
We have examined the role played by protein kinase A (PKA) in vesicle-mediated protein transport from the trans-Golgi network (TGN) to the cell surface. In vivo this transport step was inhibited by inhibitors of PKA catalytic ...
Artículo
Effect of protein kinase a activity on the association of ADP-ribosylation factor 1 to Golgi membranes
(The American Society for Biochemistry and Molecular Biology, 2000)
The small GTP-binding protein ADP-ribosylation factor 1 (ARF1) is an essential component of the molecular machinery that catalyzes the formation of membranebound transport intermediates. By using an in vitro assay that ...
Artículo
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus
(American Society for Cell Biology, 2003)
The KDEL receptor is a Golgi/intermediate compartment-located integral membrane protein that carries out the retrieval of escaped ER proteins bearing a C-terminal KDEL sequence. This occurs throughout retrograde traffic ...