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Artículo
Analysis of serial neuroblastoma PDX passages in mice allows the identification of new mediators of neuroblastoma aggressiveness
(MDPI, 2023-01-13)
Neuroblastoma is a neural crest cell-derived pediatric tumor characterized by high interand intra-tumor heterogeneity, and by a poor outcome in advanced stages. Patient-derived xenografts (PDXs) have been shown to be ...
Artículo
CD44-high neural crest stem-like cells are associated with tumour aggressiveness and poor survival in neuroblastoma tumours
(Elsevier, 2019)
BACKGROUND: Neuroblastoma is a paediatric tumour originated from sympathoadrenal precursors and characterized by its heterogeneity and poor outcome in advanced stages. Intra-tumoral cellular heterogeneity has emerged as ...
Artículo
Identification of vrk1 as a new neuroblastoma tumor progression marker regulating cell proliferation
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)
Neuroblastoma (NB) is one of the most common pediatric cancers and presents a poor survival rate in affected children. Current pretreatment risk assessment relies on a few known molecular parameters, like the amplification ...