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Artículo
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Dietary fatty acids on aortic root calcification in mice with metabolic syndrome
(Royal Society of Chemistry, 2017)
Metabolic syndrome (MetS) is associated with obesity, dyslipidemia, type 2 diabetes, and chronic low-grade inflammation. The aim of this study was to determine the role of high-fat low-cholesterol diets (HFLCDs) rich in ...
Artículo
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Exogenous fatty acids and niacin on acute prostaglandin D-2 production in human myeloid cells
(Elsevier, 2017)
Niacin activates HCA2 receptor that results in the release of PGD2. However, little is known on PGD2-producing cells and the role of fatty acids. Notably M-CSF macrophages exhibited a timely dependent PGD2 production upon ...
Artículo
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Immediate-release Niacin and a Monounsaturated Fatty Acid-rich Meal on Postprandial Inflammation and Monocyte Characteristics in Men with Metabolic Syndrome
(Elsevier, 2023)
Background & aim: When considered separately, long-term immediate-release niacin and fatty meals enriched in monounsaturated fatty acids (MUFA) decrease postprandial triglycerides, but their effects on postprandial ...
Artículo
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Minor compounds from virgin olive oil attenuate LPS-induced inflammation via visfatin-related gene modulation on primary human monocytes
(Wiley-Blackwell, 2019)
We have analyzed the effects of minor compounds found in the unsaponifiable fraction (UF) and in the phenolic fraction (PF) of virgin olive oil (VOO) on LPS-induced inflammatory response via visfatin modulation in human ...
Patente. Invención
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Composición emulsionada de grasa saturada en agua, su preparación y utilización para la evaluación de la tolerancia a los triglicéridos
(Oficina Española de Patentes y Marcas (OEPM), 2015-11-23)
Composición emulsionada de grasa saturada en agua, su preparación y utilización para la evaluación de la tolerancia a los triglicéridos. La presente invención se refiere a una composición líquida emulsionada que presenta ...
Artículo
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Unsaponifiable fraction isolated from grape (vitis vinifera l.) seed oil attenuates oxidative and inflammatory responses in human primary monocytes
(Royal Society of Chemistry, 2018)
Grape (Vitis vinifera L.) seed has well-known potential for production of oil as a byproduct of winemaking and is a rich source of bioactive compounds. Herein, we report that the unsaponifiable fraction (UF) isolated from ...
Artículo
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Olive oil and postprandial hyperlipidemia: Implications for atherosclerosis and metabolic syndrome
(Royal Society of Chemistry, 2016)
Olive oil is the primary source of fat in the Mediterranean diet, which is associated with a significant improvement in health status, as measured by reduced mortality from several chronic diseases. The current pandemic ...
Artículo
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Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPARγ-Dependent Monocyte Differentiation and Function
(Wolters Kluwer Health, 2017)
Objective-Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) mediates inflammatory and potentially proatherogenic effects, whereas the role of intracellular NAMPT (iNAMPT), the rate limiting enzyme in the salvage ...
Artículo
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The Role of DNA Damage Response in Dysbiosis-Induced Colorectal Cancer
(Multidisciplinary Digital Publishing Institute (MDPI), 2021)
The high incidence of colorectal cancer (CRC) in developed countries indicates a predominant role of the environment as a causative factor. Natural gut microbiota provides multiple benefits to humans. Dysbiosis is characterized ...