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Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
(MDPI, 2022)
Hepatobiliary tumors are a group of primary malignancies encompassing the liver, the intra- and extra-hepatic biliary tracts, and the gall bladder. Within the liver, hepatocellular carcinoma (HCC) is the most common type ...
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Neutrino-nucleus scattering in the SuSA model
(Springer, 2021)
The super-scaling approach (SuSA) model, based on the analogies between electron and neutrino interactions with nuclei, is reviewed and its application to the description of neutrino-nucleus scattering is presented. The ...
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Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
(American Society for Clinical Investigation, 2022)
New approaches for the management of glioblastoma (GBM) are an urgent and unmet clinical need. Here, we illustrate that the efficacy of radiotherapy for GBM is strikingly potentiated by concomitant therapy with the ...
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Marginality and convexity in partition function form games
(Springer Nature, 2021-08)
In this paper an order on the set of embedded coalitions is studied in detail. This allows us to define new notions of superaddivity and convexity of games in partition function form which are compared to other proposals ...
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Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors
(Taylor & Francis Open Access, 2021)
We have designed unprecedented cholinesterase inhibitors based on 1-deoxynojirimycin as potential anti-Alzheimer’s agents. Compounds are comprised of three key structural motifs: the iminosugar, for interaction with ...
Artículo
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Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing
(Elsevier, 2021)
Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol II) and needs to be resolved by DNA topoisomerases to sustain productive transcriptional elongation. ...
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Anisotropic Resistivity Surfaces Produced in ITO Films by Laser-Induced Nanoscale Self-organization
(Wiley, 2021)
Highly anisotropic resistivity surfaces are produced in indium tin oxide (ITO) films by nanoscale self-organization upon irradiation with a fs-laser beam operating at 1030 nm. Anisotropy is caused by the formation of ...
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Superscaling in the resonance region for neutrino-nucleus scattering: The SuSAv2 dynamical coupled-channels model
(American Physical Society, 2023-12-20)
In this work, the SuSAv2 and dynamical coupled-channels (DCC) models have been combined and tested in the inelastic regime for electron and neutrino reactions on nuclei. The DCC model, an approach to study baryon resonances ...
Artículo
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Teachers’ subjective happiness: testing the importance of emotional intelligence facets beyond perceived stress
(Dove Press, 2022)
Purpose: Emotional intelligence (EI) is typically linked to higher subjective happiness scores in human service professionals. It is unknown which EI facets are more predictive in explaining subjective happiness beyond ...
Artículo
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Influencers con discapacidad física en Instagram: Funciones, visibilidad y colaboración empresarial
(EPI SCP, 2022)
En el mundo digital las redes sociales adquieren importancia para las personas con discapacidad en términos de comunicación y visibilidad. Asimismo, se han convertido en el lugar idóneo para el activismo, ya que permiten ...